| 0 | - | cover | 1 | pencils: Nimit Malavia; inks: Nimit Malavia; colors: Nimit Malavia | Malcolm Reynolds; Inara Serra; Derrial Book; Kaylee Fry |
| 1 | Title Page and Credits | credits, title page | 5 | letters: typeset | |
| 2 | Foreword | foreword, introduction, preface, afterword | 2 | script: Nathan Fillion | |
| 3 | Those Left Behind, Chapter One | credits, title page | 1 | pencils: Bryan Hitch; inks: Bryan Hitch | Jayne Cobb |
| 4 | - | comic story | 22 | script: Joss Whedon, Brett Matthews; pencils: Will Conrad; inks: Will Conrad; colors: Laura Martin; letters: Michael Heisler; editing: Scott Allie | Shepherd Book; Malcom Reynolds; Zoe Washburne; Jayne Cobb; Wash [Hoban Washburne]; Kaylee [Kaywinnit Lee Frye]; Simon Tam; River Tam; Inara Serra; Ott |
| 5 | Those Left Behind, Chapter Two | credits, title page | 1 | pencils: Sean Phillips; inks: Sean Phillips | Wash [Hoban Washburne] |
| 6 | - | comic story | 22 | script: Joss Whedon, Brett Matthews; pencils: Will Conrad; inks: Will Conrad; colors: Laura Martin; letters: Michael Heisler; editing: Scott Allie | Dobson; Malcolm Reynolds; Wash [Hoban Washburne]; Jayne Cobb; Inara Serra; Kaylee [Kaywinnit Lee Frye]; Zoe Washburne; Badger; Shepherd Book; Simon Tam; River Tam |
| 7 | Those Left Behind, Chapter Three | credits, title page | 1 | pencils: J. G. Jones; inks: J. G. Jones | Inara Serra |
| 8 | - | comic story | 22 | script: Joss Whedon, Brett Matthews; pencils: Will Conrad; inks: Will Conrad; colors: Laura Martin; letters: Michael Heisler; editing: Scott Allie | Jayne Cobb; Malcom Reynolds; Wash [Hoban Washburne]; Zoë Washburne; Simon Tam; River Tam; Inara Serera; Kaylee [Kaywinnit Lee Frye]; Dobson; Shepherd Book |
| 9 | Better Days, Chapter One | credits, title page | 1 | pencils: Adam Hughes; inks: Adam Hughes | Malcom Reynolds; Zoe Washburne; Wash [Hoban Washburne] |
| 10 | - | comic story | 22 | script: Joss Whedon, Brett Matthews; pencils: Will Conrad; inks: Will Conrad; colors: Michelle Madsen; letters: Michael Heisler; editing: Scott Allie | Malcom Reynolds; Zoe Washburne; Wash [Hoban Washburne]; Inara Serra; Jayne Cobb; Kaylee [Kaywinnit Lee Frye]; Simon Tam; River Tam; Shepherd Book; Ephraim Sanda |
| 11 | Better Days, Chapter Two | credits, title page | 1 | pencils: Adam Hughes; inks: Adam Hughes | Jayne Cobb; Shepherd Book; Inara Serra |
| 12 | - | comic story | 22 | script: Joss Whedon, Brett Matthews; pencils: Will Conrad; inks: Will Conrad; colors: Michelle Madsen; letters: Michael Heisler; editing: Scott Allie | Malcom Reynolds; Zoe Washburne; Wash [Hoban Washburne]; Inara Serra; Jayne Cobb; Kaylee [Kaywinnit Lee Frye]; Simon Tam; River Tam; Shepherd Book; Ephraim Sanda |
| 13 | Better Days, Chapter Three | credits, title page | 1 | pencils: Adam Hughes; inks: Adam Hughes | Kaylee [Kaywinnit Lee Frye]; Simon Tam; River Tam |
| 14 | - | comic story | 23 | script: Joss Whedon, Brett Matthews; pencils: Will Conrad; inks: Will Conrad; colors: Michelle Madsen; letters: Michael Heisler; editing: Scott Allie | Malcolm Reynolds; Zoe Washburne; Wash [Hoban Washburne]; Inara Serra; Jayne Cobb; Kaylee [Kaywinnit Lee Frye]; Simon Tam; River Tam; Shepherd Book; Ephraim Sanda |
| 15 | The Other Half | credits, title page | 1 | pencils: Leinil Francis Yu; inks: Leinil Francis Yu | Simon Tam |
| 16 | - | comic story | 8 | script: Jim Krueger; pencils: Will Conrad; inks: Will Conrad; colors: Julius Ohta; letters: Michael Heisler; editing: Scott Allie, Sierra Hahn | Malcolm Reynolds; Zoe Washburne; Jayne Cobb; Simon Tam; River Tam |
| 17 | Downtime | credits, title page | 1 | pencils: Josh Middleton; inks: Josh Middleton | River Tam |
| 18 | - | comic story | 8 | script: Zack Whedon; pencils: Chris Samnee; inks: Chris Samnee; colors: Dave Stewart; letters: Michael Heisler | Malcolm Reynolds; Inara Serra; Zoe Washburne; Wash [Hoban washburne]; Kaylee [Kaywinnit Lee Frye]; Simon Tam; River Tam; Jayne Cobb; Derrial Book |
| 19 | The Shepherd's Tale | credits, title page | 2 | pencils: Steve Morris; inks: Steve Morris | Shepherd Derrial Book [Henry Evans]; Mr. Evans |
| 20 | - | illustration | 1 | pencils: Chris Samnee; inks: Chris Samnee; colors: Dave Stewart | Shepherd Derrial Book [Henry Evans] |
| 21 | The Shepherd's Tale | comic story | 48 | script: Joss Whedon, Zack Whedon; pencils: Chris Samnee; inks: Chris Samnee; colors: Dave Stewart; letters: Michael Heisler; editing: Scott Allie | Shepherd Derrial Book [Henry Evans] (origin, death); Mr. Evans; Malcolm Reynolds; Wash [Hoban Washburne]; Zoë Washburne; Jayne Cobb; Kaylee [Kaywinnit Lee Frye]; River Tam; Staff Sergeant Hope Claypool |
| 22 | Afterword | text article | 2 | script: Zack Whedon; pencils: Tim Bradstreet; inks: Tim Bradstreet | Shepherd Book |
| 23 | Float Out | credits, title page | 1 | pencils: Jo Chen; inks: Jo Chen | Wash [Hoban Washburne] |
| 24 | - | comic story | 24 | script: Patton Oswalt; pencils: Patric Reynolds; inks: Patric Reynolds; colors: Dave Stewart; letters: Michael Heisler; editing: Scott Allie | Wash [Hoban Washburne] (flashback); Zoë Washburne; Leland; Tagg; Trey |
| 25 | It's Never Easy | credits, title page | 1 | pencils: Daniel Dos Santos; inks: Daniel Dos Santos | Malcolm Reynolds |
| 26 | - | comic story | 10 | script: Zack Whedon; pencils: Fábio Moon; inks: Fábio Moon; colors: Cris Peter; letters: Michael Heisler; editing: Scott Allie, Sierra Hahn | Malcolm Reynolds; Zoe Washburne; Frosty; River Tam; Simon Tam; Jayne Cobb; Kaylee [Kaywinnit Lee Frye]; Inara Serra |
| 27 | Cover Gallery | credits, title page | 2 | pencils: Jo Chen; inks: Jo Chen | Kaylee [Kaywinnit Lee Frye]; Inara Serra; River Tam |
| 28 | Mal Reynolds Cover | cover reprint (on interior page) | 1 | pencils: John Cassaday; inks: John Cassaday; colors: Laura Martin | Malcolm Reynolds |
| 29 | Zoe Cover | cover reprint (on interior page) | 1 | pencils: Joe Quesada; inks: Danny Miki; colors: Richard Isanove | Zoe Washburne |
| 30 | Wash Cover | cover reprint (on interior page) | 1 | pencils: Sean Phillips; inks: Sean Phillips; colors: Sean Phillips | Wash [Hoban Washburne] |
| 31 | Inara Cover | cover reprint (on interior page) | 1 | pencils: J. G. Jones; inks: J. G. Jones; colors: Laura Martin | Inara Serra |
| 32 | Kaylee Cover | cover reprint (on interior page) | 1 | pencils: Jo Chen; inks: Jo Chen; colors: Jo Chen | Kaylee [Kaywinnit Lee Frye] |
| 33 | Jayne Cover | cover reprint (on interior page) | 1 | pencils: Bryan Hitch; inks: Bryan Hitch; colors: Laura Martin | Jayne Cobb |
| 34 | Simon Tam Cover | cover reprint (on interior page) | 1 | pencils: Leinil Yu; inks: Leinil Yu; colors: Leinil Yu | Simon Tam |
| 35 | River Cover | cover reprint (on interior page) | 1 | pencils: Josh Middleton; inks: Josh Middleton; colors: Josh Middleton | River Tam |
| 36 | Shepherd Book Cover | cover reprint (on interior page) | 1 | pencils: Tim Bradstreet; inks: Tim Bradstreet; colors: Grant Goleash | Shepherd Book |
| 37 | Serenity #1 - Those Left Behind | cover reprint (on interior page) | 1 | pencils: Adam Hughes; inks: Adam Hughes; colors: Adam Hughes | Malcolm Reynolds; Inara |
| 38 | Serenity Better Days #1 | cover reprint (on interior page) | 1 | pencils: Adam Hughes; inks: Adam Hughes; colors: Adam Hughes | Malcom Reynolds; Zoe Washburne; Wash [Hoban Washburne] |
| 39 | Serenity Better Days #2 | cover reprint (on interior page) | 1 | pencils: Adam Hughes; inks: Adam Hughes; colors: Adam Hughes | Jayne Cobb; Shepherd Book; Inara Serra |
| 40 | Serenity Better Days #3 | cover reprint (on interior page) | 1 | pencils: Adam Hughes; inks: Adam Hughes; colors: Adam Hughes | Kaylee [Kaywinnit Lee Frye]; Simon Tam; River Tam |
| 41 | Serenity: Firefly Class 03-K64 #2 - Better Days and Other Stories | cover reprint (on interior page) | 1 | pencils: Jo Chen; inks: Jo Chen; colors: Jo Chen | Kaylee [Kaywinnit Lee Frye]; Inara Serra; River Tam |
| 42 | Serenity: Firefly Class 03-K64 #3 - The Shepherd's Tale | cover reprint (on interior page) | 1 | pencils: Steve Morris; inks: Steve Morris; colors: Steve Morris | Shepherd Derrial Book [Henry Evans]; Mr. Evans |
| 43 | Free Comic Book Day: Star Wars / and Serenity: Firefly Class 03-K64 | cover reprint (on interior page) | 1 | pencils: Daniel Dos Santos; inks: Daniel Dos Santos; colors: Daniel Dos Santos | Malcolm Reynolds |
| 44 | Serenity: Float Out Cover A | cover reprint (on interior page) | 1 | pencils: Jo Chen; inks: Jo Chen; colors: Jo Chen | Wash [Hoban Washburne] |
| 45 | Serenity: Float Out Cover B | cover reprint (on interior page) | 1 | pencils: Frank Stockton; inks: Frank Stockton; colors: Frank Stockton | Wash [Hoban Washburne] |