| 0 | - | cover | 1 | pencils: Christian Ward; inks: Christian Ward; colors: Christian Ward | River Tam, Simon Tam |
| 1 | Endpapers | blank page(s) | 2 | | |
| 2 | - | illustration | 1 | | |
| 3 | Title Page | credits, title page | 1 | letters: typeset | |
| 4 | Copyright Page | credits, title page | 2 | pencils: Andrés Genolet; inks: Andrés Genolet | |
| 5 | Credits | credits, title page | 2 | pencils: Andrés Genolet; inks: Andrés Genolet | |
| 6 | Firefly River Run | credits, title page | 2 | pencils: Adam Gorham; inks: Adam Gorham | |
| 7 | - | illustration | 1 | pencils: Andrés Genolet; inks: Andrés Genolet | Simon Tam |
| 8 | River Run | comic story | 40 | script: David M. Booher; pencils: Andrés Genolet; inks: Andrés Genolet; colors: Mattia Iacono; letters: Jim Campbell | River Tam, Simon Tam |
| 9 | - | illustration | 1 | | |
| 10 | The Firefly Holiday Special | credits, title page | 2 | pencils: Daniel Warren Johnson; inks: Daniel Warren Johnson | |
| 11 | - | illustration | 1 | | |
| 12 | - | comic story | 40 | script: Jeff Jensen; pencils: Jordi Pérez, Vincenzo Federici, Fabiana Mascolo; inks: Jordi Pérez, Vincenzo Federici, Fabiana Mascolo; colors: Francesco Segala, Lucia Di Giammarino, Fabiana Mascolo, Gloria Martinelli; letters: Jim Campbell | Shepherd Book, Jayne Cobb, Kaylee Frye, Malcolm Reynolds, Inara Serra, River Tam, Simon Tam, Emma Washburne, Wash, Zoë Alleyne Washburne |
| 13 | - | illustration | 1 | | |
| 14 | Cover Gallery | credits, title page | 2 | pencils: Caitlin Yarsky; inks: Caitlin Yarsky | Kaylee Frye, Simon Tam |
| 15 | Firefly River Run #1 Main Cover | cover reprint (on interior page) | 1 | pencils: Christian Ward; inks: Christian Ward; colors: Christian Ward | River Tam, Simon Tam |
| 16 | Firefly River Run #1 Variant Cover | cover reprint (on interior page) | 1 | pencils: Adam Gorham; inks: Adam Gorham; colors: Adam Gorham | River Tam |
| 17 | The Firefly Holiday Special #1 Main Cover | cover reprint (on interior page) | 1 | pencils: InHyuk Lee; inks: InHyuk Lee; colors: InHyuk Lee | Jayne Cobb |
| 18 | The Firefly Holiday Special #1 Variant Cover | cover reprint (on interior page) | 1 | pencils: Caitlin Yarsky; inks: Caitlin Yarsky; colors: Caitlin Yarsky | Kaylee Frye, Simon Tam |
| 19 | The Firefly Holiday Special #1 Variant Cover | cover reprint (on interior page) | 1 | pencils: Daniel Warren Johnson; inks: Daniel Warren Johnson; colors: Mike Spicer | Jayne Cobb, Kaylee Frye, Malcolm Reynolds, Inara Serra, River Tam, Simon Tam, Wash, Zoë Alleyne Washburne |
| 20 | - | illustration | 1 | | |
| 21 | Script to Page: Firefly River Run #1 | text article | 10 | script: David M. Booher; pencils: Andrés Genolet; inks: Andrés Genolet; colors: Mattia Iacono | |
| 22 | Discover Visionary Creators | promo (ad from the publisher) | 1 | script: ? (promo copy); pencils: various; inks: various; colors: various; letters: typeset | |
| 23 | - | illustration | 1 | | |
| 24 | Endpapers | blank page(s) | 2 | | |
| 26 | Back Cover | promo (ad from the publisher) | 1 | script: ? (promo copy); ? as CBR (cover quote); ? as Fanbase Press (cover quote); letters: typeset | |