| 0 | - | cover | 1 | pencils: Fábio Moon; inks: Fábio Moon; colors: Fábio Moon | |
| 1 | Title and Credits | credits, title page | 6 | script: Daniel Chabon, Chuck Howitt; pencils: Fábio Moon; inks: Fábio Moon; colors: Fábio Moon | |
| 2 | A Study in Emerald | cover reprint (on interior page) | 1 | pencils: Rafael Albuquerque; inks: Rafael Albuquerque; colors: Dave Stewart | |
| 3 | The New Friend / The Room / The Palace / The Performance / The Skin and the Pit | credits, title page | 5 | | |
| 4 | A Study in Emerald | comic story | 63 | script: Neil Gaiman, Rafael Scavone, Rafael Albuquerque; pencils: Rafael Albuquerque; inks: Rafael Albuquerque; colors: Dave Stewart; letters: Todd Klein; editing: Daniel Chabon, Brett Israel | James Moriarty; Sebastian Moran; Lestrade; Sherlock Holmes; John Watson |
| 5 | Fill-in Page | illustration | 1 | pencils: Cindy Cacerez-Sprague; inks: Cindy Cacerez-Sprague; colors: Cindy Cacerez-Sprague | |
| 6 | Murder Mysteries | cover reprint (on interior page) | 1 | pencils: P. Craig Russell; inks: P. Craig Russell; colors: P. Craig Russell | |
| 7 | Prologue | credits, title page | 1 | | |
| 8 | Murder Mysteries | comic story | 62 | script: Neil Gaiman, P. Craig Russell; pencils: P. Craig Russell; inks: P. Craig Russell; colors: Lovern Kindzierski; letters: Galen Showman; editing: Scott Allie, Daniel Chabon | Raguel; Lucifer; Carasel; Phanuel; Saraquael; Zephkiel; Azazel |
| 9 | Murder Mysteries | credits, title page | 2 | pencils: P. Craig Russell; inks: P. Craig Russell | |
| 10 | Lucifer | illustration | 1 | pencils: P. Craig Russell; inks: P. Craig Russell | Lucifer |
| 11 | Fill-in Page | illustration | 1 | pencils: Cindy Cacerez-Sprague; inks: Cindy Cacerez-Sprague; colors: Cindy Cacerez-Sprague | |
| 12 | How to Talk to Girls at Parties | cover reprint (on interior page) | 1 | pencils: Fábio Moon; inks: Fábio Moon; colors: Fábio Moon | Wain's Wain; Stella |
| 13 | - | blank page(s) | 1 | | |
| 14 | How to Talk to Girls at Parties | comic story | 60 | script: Neil Gaiman, Fábio Moon, Gabriel Bá; pencils: Fábio Moon; inks: Fábio Moon; colors: Fábio Moon; letters: Fábio Moon; editing: Diana Schutz, Aaron Walker | Vic; Enn; Stella; Wain's Wain; Triolet |
| 15 | Enn & Vic | illustration | 1 | pencils: Fábio Moon; inks: Fábio Moon | Enn; Vic |
| 16 | Fill-in Page | illustration | 1 | pencils: Cindy Cacerez-Sprague; inks: Cindy Cacerez-Sprague; colors: Cindy Cacerez-Sprague | |
| 17 | Forbidden Brides of the Faceless Slaves in the Secret House of the Night of Dread Desire | cover reprint (on interior page) | 1 | pencils: Shane Oakley; inks: Shane Oakley; colors: Shane Oakley | |
| 18 | - | blank page(s) | 1 | | |
| 19 | Forbidden Brides of the Faceless Slaves in the Secret House of the Night of Dread Desire | comic story | 38 | script: Neil Gaiman, Shane Oakley; pencils: Shane Oakley; inks: Shane Oakley; colors: Nick Filardi; letters: Todd Klein; editing: Daniel Chabon, Cardner Clark | The author; Amelia Earnshawe; the caretaker; Toombes; Ethel; George Earnshawe |
| 20 | Bonus Content | credits, title page | 1 | letters: typeset | |
| 21 | A Study in Emerald [Sketchbook] | illustration | 10 | pencils: Rafael Albuquerque; inks: Rafael Albuquerque; letters: Rafael Albuquerque | |
| 22 | Mysteries Demystified | text article | 23 | script: Durwin S. Talon, P. Craig Russell; pencils: P. Craig Russell; inks: P. Craig Russell; colors: Lovern Kindzierski; letters: Galen Showman | |
| 23 | Murder Mysteries Sketchbook | illustration | 15 | script: P. Craig Russell, Neil Gaiman; pencils: P. Craig Russell; inks: P. Craig Russell; colors: Lovern Kindzierski; letters: P. Craig Russell; editing: Daniel Chabon | |
| 24 | Forbidden Brides Sketchbook | illustration | 6 | script: Shane Oakley; pencils: Shane Oakley; inks: Shane Oakley; colors: Shane Oakley | The author; Amelia Earnshawe; Toombes; the caretaker |
| 25 | Back Cover | promo (ad from the publisher) | 1 | script: Daniel Chabon, Chuck Howitt | |