| 0 | - | cover | 1 | pencils: Ryan Sook; inks: Ryan Sook; colors: Ryan Sook | |
| 1 | - | insert or dust jacket | 0 | pencils: Jack Sparling, Joe Orlando; inks: Jack Sparling, Joe Orlando | Cain |
| 2 | Title Page | credits, title page | 1 | pencils: Neal Adams, Win Mortimer, Alex Toth; inks: Neal Adams, George Roussos, Alex Toth | |
| 3 | - | credits, title page | 1 | pencils: Alex Toth, Mike Sekowsky, Gil Kane, Win Mortimer; inks: Alex Toth, Wally Wood, George Roussos, Carl Anderson | |
| 4 | Table of Contents | table of contents | 6 | letters: typeset | |
| 5 | Foreword | foreword, introduction, preface, afterword | 4 | script: Michael Uslan; pencils: Jerry Grandenetti, Bill Draut, Tony DeZuniga, Nestor Redondo, Alex Toth; inks: Jerry Grandenetti, Bill Draut, Tony DeZuniga, Nestor Redondo, Alex Toth, Wally Wood | |
| 6 | House of Mystery #174 | cover reprint (on interior page) | 1 | pencils: Carmine Infantino, Joe Orlando, George Roussos; inks: Joe Orlando, George Roussos; letters: Gaspar Saladino | |
| 7 | The Wondrous Witch's Cauldron | comic story | 3.5 | pencils: Lee Elias; inks: Lee Elias | |
| 8 | The Man Who Hated Good Luck! | comic story | 5.5 | pencils: Doug Wildey; inks: Doug Wildey | |
| 9 | Page 13 | illustration | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 10 | Museum of Worthless Inventions | comic story | 5.67 | script: Otto Binder; pencils: Bernard Baily; inks: Bernard Baily | Professor Amos Todd |
| 11 | The Court of Creatures | comic story | 8.5 | script: Jack Miller; pencils: Carmine Infantino; inks: Mort Meskin | Mark Merlin; Elsa; Cottswald Creatures |
| 12 | House of Mystery #175 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Neal Adams, Jack Adler | |
| 13 | Welcome to the House of Mystery | comic story | 1 | script: Joe Orlando; pencils: Joe Orlando; inks: Joe Orlando | Cain (first appearance) |
| 14 | The Gift of-- Doom | comic story | 7.67 | pencils: George Roussos; inks: George Roussos | Roger Steele |
| 15 | All Alone | text story | 2 | pencils: Joe Orlando; inks: Joe Orlando | |
| 16 | Page 13 | activity | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 17 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 18 | The House of Gargoyles | comic story | 11.67 | script: Jack Oleck; pencils: Jack Sparling; inks: Jack Sparling | Cain (host); Francois (sculptor, flashback); French sculptor; Jimmy; Samuel |
| 19 | House of Mystery #176 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Neal Adams, Jack Adler | |
| 20 | Welcome... to the House of Mystery! | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Joe Orlando; inks: Joe Orlando; letters: Milt Snapinn | Cain |
| 21 | The House of No Return! | comic story | 7.67 | pencils: Sid Greene; inks: Sid Greene; letters: Stan Starkman | |
| 22 | Page 13 | comic story | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 23 | - | cartoon | 3 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 24 | The Roots of Evil! | comic story | 10 | script: Marv Wolfman; pencils: Jack Sparling; inks: Jack Sparling | |
| 25 | House of Mystery #177 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Neal Adams, Jack Adler | |
| 26 | The Son of the Montross Monster | comic story | 7.67 | pencils: Mort Meskin; inks: George Roussos, Mort Meskin | Cain (host - inserted for this reprint, does not appear in original) |
| 27 | Welcome Fellow Tenants! | activity | 1 | script: Joe Orlando; pencils: Joe Orlando; inks: Joe Orlando | Cain |
| 28 | Odds and Ends from... Cain's Cellar | comic story | 1 | | Cain (guide) |
| 29 | Does Your Hand Have Any of These Lines? | illustration | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 30 | Last Meal | text story | 2 | script: Charles King; pencils: Joe Orlando; inks: Joe Orlando | |
| 31 | The Curse of the Cat | comic story | 10 | script: Howie Post; pencils: Bill Draut; inks: Bill Draut | Cain |
| 32 | - | cartoon | 2 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 33 | House of Mystery #178 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Neal Adams, Jack Adler | |
| 34 | Welcome to the House of Mystery | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Joe Orlando; inks: Joe Orlando; letters: John Duffy | Cain |
| 35 | The Game | comic story | 6.67 | script: Neal Adams; pencils: Neal Adams; inks: Neal Adams; letters: John Duffy | Jaime Markus |
| 36 | The Man Who Haunted a Ghost! | comic story | 6 | pencils: Jim Mooney; inks: Jim Mooney; letters: Pat Gordon | |
| 37 | Page 13 | cartoon | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés; letters: Gaspar Saladino | |
| 38 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 39 | What's the Youth? | comic story | 8 | script: E. Nelson Bridwell; pencils: Win Mortimer; inks: George Roussos; letters: Joe Letterese | Cain |
| 40 | Ghostly Miners | comic story | 1 | | |
| 41 | House of Mystery #179 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Neal Adams, Jack Adler | |
| 42 | Welcome to the House of Mystery | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Joe Orlando; inks: Joe Orlando | |
| 43 | Sour Note! | comic story | 6 | script: E. Nelson Bridwell; pencils: Jerry Grandenetti; inks: George Roussos; letters: Ira Schnapp | Cain |
| 44 | The Man Who Murdered Himself! | comic story | 3 | script: Marv Wolfman; pencils: Bernie Wrightson; inks: Bernie Wrightson; letters: Ray Holloway | Cain |
| 45 | Roll The Lucky Dice! | activity | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés; letters: Gaspar Saladino | |
| 46 | - | cartoon | 1.17 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 47 | The Widow's Walk | comic story | 10 | script: Howard Post; pencils: Neal Adams; inks: Joe Orlando; letters: Ben Oda | Angus Beame; Mary Bourne; Mr. Bourne (Mary's father); Homer Clyde (Mr. Bourne's servant); Mildred Clyde (Homer's wife); lawyer; various crewmen of Angus Beame; exotic item merchant; modern-day beachgoers |
| 48 | The Dead Tell Tales | comic story | 0.67 | script: Otto Binder; pencils: Morris Waldinger; inks: Tom Nicolosi; letters: Ira Schnapp | |
| 49 | House of Mystery #180 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Neal Adams, Jack Adler | |
| 50 | Comes a Warrior | comic story | 9.67 | script: Gil Kane; pencils: Gil Kane; inks: Wally Wood; letters: Milt Snapinn | Rangarry; Cain |
| 51 | His Name Is... Kane | comic story | 6.5 | script: Mike Friedrich; pencils: Gil Kane; inks: Wally Wood; letters: Milt Snapinn | Abel; Carmine Infantino; Gil Kane; Joe Orlando |
| 52 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 53 | Oscar Horns In! | text story | 2 | script: Cliff Rhodes; pencils: Joe Orlando; inks: Joe Orlando | |
| 54 | Scared to Life | comic story | 3 | script: Marv Wolfman; pencils: Bernie Wrightson; inks: Bernie Wrightson | Cain |
| 55 | - | cartoon | 1.67 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 56 | Cain's True Case Files | cartoon | 1 | pencils: Morris Waldinger; inks: Morris Waldinger; letters: Morris Waldinger | |
| 57 | House of Mystery #181 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Neal Adams, Jack Adler | |
| 58 | Sir Greeley's Revenge! | comic story | 11.17 | script: Otto Binder; pencils: Jack Sparling; inks: Jack Sparling; letters: John Costanza | Cain (host) |
| 59 | Page 13 | illustration | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 60 | The Siren of Satan | comic story | 10 | script: Robert Kanigher; pencils: Bernie Wrightson; inks: Bernie Wrightson; letters: John Costanza | Cain (host) |
| 61 | - | cartoon | 0.67 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 62 | House of Mystery #182 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Neal Adams, Jack Adler | Cain (inset) |
| 63 | The Devil's Doorway | comic story | 10.67 | script: Jack Oleck; pencils: Alex Toth; inks: Alex Toth; letters: John Costanza | Cain (host); Satan [Belial] |
| 64 | Grave Results! | comic story | 3 | script: Marv Wolfman; pencils: Wayne Howard; inks: Wayne Howard; letters: Gaspar Saladino | Cain |
| 65 | - | promo (ad from the publisher) | 1 | script: Joe Orlando; pencils: Jerry Grandenetti; inks: Dick Giordano | Cain; Gregory the gargoyle |
| 66 | - | cartoon | 0.5 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 67 | The Hound of Night! | comic story | 7.67 | script: Robert Kanigher; pencils: Jerry Grandenetti; inks: Jerry Grandenetti; letters: Milt Snapinn | Cain; Sir Charles; Sir Edwin; James |
| 68 | House of Mystery #183 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Neal Adams, Jack Adler | |
| 69 | Welcome to the House of Mystery | comic story | 1 | script: Joe Orlando; pencils: Joe Orlando; inks: Joe Orlando; letters: Milt Snapinn | Cain |
| 70 | The Haunting! | comic story | 5 | script: Jack Oleck; pencils: Jerry Grandenetti; inks: Jerry Grandenetti; letters: John Costanza | Cain; Frank Abel; Peggy Abel |
| 71 | - | cartoon | 0.67 | script: John Albano; pencils: John Albano; inks: John Albano | |
| 72 | Curse of the Blankenships | comic story | 0.5 | pencils: Bernard Baily; inks: Bernard Baily; letters: Ira Schnapp | |
| 73 | Superstitions about Spiders | cartoon | 0.5 | script: Julius Schwartz; pencils: Morris Waldinger; inks: Tom Nicolosi | |
| 74 | The Dead Can Kill! | comic story | 3 | script: Marv Wolfman; pencils: Bernie Wrightson; inks: Bernie Wrightson; letters: Ray Holloway | Rev. Charles Power; Rawley; Cain |
| 75 | Horoscope | text article | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 76 | - | cartoon | 1.5 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 77 | Secret of the Whale's Vengeance | comic story | 11.67 | script: Robert Kanigher; pencils: Jerry Grandenetti; inks: Wally Wood; letters: John Costanza | Cain; Jeremy Bridges; Austin Bridges |
| 78 | House of Mystery #184 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Jack Adler | Cain (inset) |
| 79 | - | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Alex Toth; inks: Alex Toth; letters: Alex Toth | Cain |
| 80 | Turner's Treasure | comic story | 10 | script: Jack Oleck; pencils: Alex Toth; inks: Alex Toth; letters: Alex Toth | Cain (host) |
| 81 | Diploma | activity | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 82 | The Eyes of the Basilisk! | comic story | 9.67 | script: E. Nelson Bridwell; pencils: Gil Kane; inks: Wally Wood | Cain (host) |
| 83 | - | cartoon | 1.5 | script: John Albano; pencils: John Albano; inks: John Albano | |
| 84 | House of Mystery #185 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams | Cain (inset) |
| 85 | Boom! | comic story | 8 | script: Jerry Grandenetti; pencils: Jerry Grandenetti; inks: Jerry Grandenetti; letters: Milt Snapinn | Cain |
| 86 | - | cartoon | 0.67 | script: John Albano; pencils: John Albano; inks: John Albano | |
| 87 | Room 13 | activity | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 88 | Voice from the Dead... | comic story | 3 | pencils: Wayne Howard; inks: Wayne Howard; letters: Ray Holloway | Cain (host) |
| 89 | - | cartoon | 0.5 | script: Joe Orlando; pencils: Joe Orlando; inks: Joe Orlando | |
| 90 | The Beautiful Beast | comic story | 11 | script: Joe Gill; pencils: Al Williamson; inks: Al Williamson | Cain (host) |
| 91 | House of Mystery #186 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams | |
| 92 | The Secret of the Egyptian Cat | comic story | 10 | script: Robert Kanigher; pencils: Bernie Wrightson; inks: Bernie Wrightson; letters: Irving Watanabe | Cain (story host); Isha (priestess); Konassos (sorcerer); Ra-Na (cat) |
| 93 | Room 13 | activity | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 94 | - | cartoon | 2 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 95 | Nightmare | comic story | 12 | script: Robert Kanigher; pencils: Neal Adams, Joe Orlando; inks: Neal Adams, Joe Orlando; letters: John Costanza | Cain (story host); Judy; Judy's father; Miss Winter (governess); Pan (statue brought to life) |
| 96 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 97 | House of Mystery #187 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Jack Adler | |
| 98 | Mask of the Red Fox | comic story | 11.17 | script: Robert Kanigher; pencils: Alex Toth; inks: Alex Toth; letters: Alex Toth | |
| 99 | Page 13 | activity | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 100 | Appointment Beyond the Grave! | comic story | 3 | pencils: Wayne Howard; inks: Wayne Howard | |
| 101 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 102 | An Aura of Death! | comic story | 7 | pencils: John Celardo; inks: Mike Peppe; letters: Milt Snapinn | |
| 103 | - | comic story | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 104 | House of Mystery #188 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams | |
| 105 | Dark City of Doom | comic story | 11.67 | script: Gerard Conway; pencils: Tony DeZuniga; inks: Tony DeZuniga; letters: John Costanza | Cain (Host) |
| 106 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 107 | Coffin Cut-Out | activity | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 108 | - | cartoon | 1 | script: John Albano; pencils: John Albano; inks: John Albano | |
| 109 | House of Madness! | comic story | 8 | pencils: Bernie Wrightson; inks: Bernie Wrightson; letters: Milt Snapinn | |
| 110 | The Fly | comic story | 0.67 | script: John Albano; pencils: John Albano; inks: John Albano | |
| 111 | House of Mystery #189 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Jack Adler | |
| 112 | Surprise! | foreword, introduction, preface, afterword | 2 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | Cain |
| 113 | Eyes of the Cat | comic story | 12 | script: Robert Kanigher; pencils: Jerry Grandenetti; inks: Wally Wood; letters: Ben Oda | Cain (host) |
| 114 | The Deadly Game of G-H-O-S-T | comic story | 5.67 | pencils: Leonard Starr; inks: Leonard Starr; letters: Pat Gordon | |
| 115 | The Thing in the Chair | comic story | 6 | script: Jack Oleck; pencils: Tom Sutton; inks: Tom Sutton; letters: Ben Oda | Cain (host) |
| 116 | House of Mystery #190 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams; colors: Jack Adler; letters: Gaspar Saladino | |
| 117 | Welcome to the House of Mystery | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés; letters: Ben Oda | Cain; Gregory the Gargoyle |
| 118 | Fright! | comic story | 10 | script: Robert Kanigher; pencils: Alex Toth; inks: Alex Toth; letters: John Costanza | Cain (host) |
| 119 | Room 13 | activity | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés; letters: Ben Oda | Cain |
| 120 | - | cartoon | 1 | script: John Albano; pencils: John Albano; inks: John Albano | |
| 121 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 122 | A Witch Must Die! | comic story | 9.67 | script: Jack Miller; pencils: Ric Estrada; inks: Frank Giacoia; letters: Ben Oda | |
| 123 | House of Mystery #191 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams | |
| 124 | No Strings Attached! | comic story | 11 | script: Len Wein; pencils: Bill Draut; inks: Bill Draut; letters: Milt Snapinn | Cain (host) |
| 125 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 126 | The Hanging Tree! | comic story | 6 | script: Jack Oleck; pencils: Tony DeZuniga; inks: Tony DeZuniga; letters: Ray Holloway | Cain (host) |
| 127 | Night Prowler! | comic story | 3 | script: Len Wein; pencils: Bernie Wrightson; inks: Bernie Wrightson | |
| 128 | House of Mystery #192 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams | |
| 129 | The Gardener of Eden! | comic story | 10 | script: John Albano; pencils: Jim Aparo; inks: Jim Aparo; letters: Jim Aparo | |
| 130 | - | cartoon | 1 | script: Lore Shoberg; pencils: Lore Shoberg; inks: Lore Shoberg | |
| 131 | Image of Darkness | comic story | 7 | script: Robert Kanigher; pencils: Gray Morrow; inks: Gray Morrow; letters: John Costanza | |
| 132 | Nobody Loves a Lizard! | comic story | 4 | script: Virgil North; pencils: Don Heck; inks: Don Heck; letters: Milt Snapinn | |
| 133 | House of Mystery #193 | cover reprint (on interior page) | 1 | pencils: Bernie Wrightson; inks: Bernie Wrightson | |
| 134 | Voodoo Vengeance! | comic story | 13 | script: Alan Riefe; pencils: Tony DeZuniga; inks: Tony DeZuniga; letters: Ben Oda | |
| 135 | Dark Night, Dark Dreams! | comic story | 7 | script: Francis X. Bushmaster; pencils: Bill Draut; inks: Tom Palmer; letters: Milt Snapinn | |
| 136 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 137 | The Hero | comic story | 1 | script: Lore Shoberg; pencils: Lore Shoberg; inks: Lore Shoberg | |
| 138 | House of Mystery #194 | cover reprint (on interior page) | 1 | pencils: Bernie Wrightson; inks: Bernie Wrightson | |
| 139 | Born Loser | comic story | 9.67 | script: Jack Oleck; pencils: Alex Toth; inks: Alex Toth; letters: Alex Toth | Cain (host) |
| 140 | The Human Wave | comic story | 8 | pencils: Russ Heath; inks: Russ Heath; letters: Gaspar Saladino | |
| 141 | The Negative Man | comic story | 8 | script: Jack Kirby; pencils: Jack Kirby; inks: Jack Kirby; letters: Pat Gordon | |
| 142 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 143 | Midnight Snack | cartoon | 1 | script: John Costanza; pencils: John Costanza; inks: John Costanza; letters: John Costanza | Cain |
| 144 | The King Is Dead | comic story | 10 | script: Jack Oleck; pencils: Nestor Redondo; inks: Nestor Redondo | Cain (host) |
| 145 | House of Mystery #195 | cover reprint (on interior page) | 1 | pencils: Bernie Wrightson; inks: Bernie Wrightson | |
| 146 | Welcome to the House of Mystery! | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | Cain; Gregory the Gargoyle |
| 147 | Bat Out of Hell | comic story | 8 | script: Jack Oleck; pencils: Nestor Redondo; inks: Nestor Redondo | Cain (host); Adam Leach |
| 148 | The Fantastic Wishing Well | comic story | 5.67 | pencils: Mort Meskin; inks: George Roussos, Mort Meskin; letters: Artie Simek | Brad Horton |
| 149 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 150 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 151 | Countdown! | comic story | 3 | script: Len Wein; pencils: Ralph Reese; inks: Ralph Reese; letters: Milt Snapinn | Cain (host); Jason; Valerie; Peter |
| 152 | Things Old... Things Forgotten | comic story | 10 | pencils: Bernie Wrightson; inks: Bernie Wrightson; letters: Ben Oda | Cain (host); Igor Lazlo; Gork; Eric Roder; Hans |
| 153 | Who Am I? | comic story | 6 | pencils: Bernard Baily; inks: Bernard Baily | |
| 154 | Trick or Treat | comic story | 1.5 | pencils: Michael Wm. Kaluta; inks: Michael Wm. Kaluta; letters: Ray Holloway | |
| 155 | House of Mystery #196 | cover reprint (on interior page) | 1 | pencils: Tony DeZuniga; inks: Tony DeZuniga | |
| 156 | A Girl and Her Dog | comic story | 9 | script: Gerry Conway; pencils: Gray Morrow; inks: Gray Morrow; letters: John Costanza | Cain (host); Peter (dog); Michael; Lissa; Miss Cruthers |
| 157 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 158 | The Alien Within Me | comic story | 7.67 | pencils: Alex Toth; inks: Alex Toth; letters: Stan Starkman | Professor Vraney; Professor Adams |
| 159 | Child of the Dead! | comic story | 2 | script: Jack Oleck; pencils: Wayne Howard; inks: Wayne Howard; letters: Milt Snapinn | Cain (host); Walter Scott |
| 160 | Cain's Room 13 | cartoon | 1 | script: Lore Shoberg; pencils: Lore Shoberg; inks: Lore Shoberg | |
| 161 | Dark Journey | comic story | 6 | pencils: Nick Cardy; inks: Nick Cardy; letters: Pat Gordon | |
| 162 | My Heart Becomes So Icy Cold | text story | 1 | script: Len Wein; pencils: Tony DeZuniga; inks: Tony DeZuniga; letters: Ben Oda | |
| 163 | The Little People! | comic story | 10 | script: Jack Oleck; pencils: Gil Kane; inks: Frank Giacoia; letters: Milt Snapinn | Cain (host); Michael O'Bannion |
| 164 | House of Mystery #197 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams | |
| 165 | Ghost Ship | comic story | 12.34 | script: Jack Oleck; pencils: Jack Sparling; inks: Jack Sparling; letters: Ben Oda | Cain (host); John Dodson; Jamie; Captain Jonah Frame; Fenton |
| 166 | Mr. Mortem! | comic story | 5.67 | pencils: Leonard Starr; inks: Leonard Starr | Vera; Drew Wilson; Conrad Wilson; Mr. Mortem; Biff Saunders |
| 167 | I Wish I May, I Wish I Might | comic story | 3.5 | script: Len Wein; pencils: Dick Dillin; inks: Frank Giacoia; letters: Charlotte Jetter | Mark Wagner; Genie |
| 168 | - | cartoon | 1 | script: Lore Shoberg; pencils: Lore Shoberg; inks: Lore Shoberg | |
| 169 | House of Horrors | comic story | 8 | script: Jack Oleck; pencils: Nestor Redondo; inks: Nestor Redondo | Cain (host); Frank Cannon; Anna Vargas; Catherine Vargas; Jan Vargas |
| 170 | The Guardian of the Past | comic story | 6 | pencils: Nick Cardy; inks: Nick Cardy; letters: Pat Gordon | Mr. Haver; Orab; Gamel; Rami |
| 171 | House of Mystery #198 | cover reprint (on interior page) | 1 | pencils: Nick Cardy; inks: Nick Cardy | |
| 172 | Two Lives to Live! | comic story | 11.67 | script: Jack Oleck; pencils: Mike Sekowsky; inks: Nick Cardy; letters: Milt Snapinn | Cain (host); Ian Lerner; Satan; Luisa |
| 173 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 174 | He Adopted a Martian Boy | comic story | 6 | pencils: Bernard Baily; inks: Bernard Baily | Cain (host); Fred Marshal; Akza |
| 175 | Brief Visit | comic story | 4 | script: Sam Glanzman; pencils: Sam Glanzman; inks: Sam Glanzman; letters: Sam Glanzman | Cain (host); Satan; Nilats (demon); Itepal (demon); Reltih (demon) |
| 176 | Cain's Room 13 | cartoon | 1 | script: Lore Shoberg; pencils: Lore Shoberg; inks: Lore Shoberg | |
| 177 | The Day of the Demon! | comic story | 8 | script: Archie Goodwin; pencils: Mike Sekowsky; inks: Carl Anderson; letters: Ben Oda | Cain (host); Mordok; Gustav Tablun; Peter Kurt; Erica; Stefan |
| 178 | The Thing in the Telescope | comic story | 6 | pencils: Mort Meskin; inks: Mort Meskin | Detective-Lieutenant John Hollis; Oswald Freems; Willy; Jack |
| 179 | House of Mystery #199 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams | |
| 180 | Sno' Fun! | comic story | 9 | script: Sergio Aragonés; pencils: Wally Wood; inks: Wally Wood; letters: John Costanza | Cain (story host); Gregory (gargoyle); Dr. Wallace B. Peterson (scientist); Professor Strauss (scientist) |
| 181 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 182 | He Doomed The World! | comic story | 8 | pencils: Jack Kirby; inks: Jack Kirby; letters: Pat Gordon | Cain (host); Frank Cable; Mr. Hiller; Mr. Lollar; Mr. Carlson; Mr. Hogarth |
| 183 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | Cain; Gregory |
| 184 | Snow Beast | comic story | 8 | script: Lynn Marron; pencils: Rich Buckler; inks: Rich Buckler; letters: John Costanza | Cain (host); Kirk; Sam; Nita; Su-Ka-Tae (Abominable Snowman) |
| 185 | The Whole Ball of Tin | comic story | 7 | script: Len Wein, Gerry Conway; pencils: Bob Oksner; inks: Bob Oksner; letters: John Costanza | Cain (host); Wilson Brown; J. Frederic Brown |
| 186 | The Haunting Wind! | comic story | 3.67 | script: Jack Miller; pencils: John Giunta; inks: John Giunta; letters: Gaspar Saladino | Cain; Dan Russell; Jim Nelson |
| 187 | House of Mystery #200 | cover reprint (on interior page) | 1 | pencils: Michael Wm. Kaluta; inks: Michael Wm. Kaluta | |
| 188 | - | foreword, introduction, preface, afterword | 1 | script: Len Wein; pencils: MW Kaluta; inks: MW Kaluta; letters: Milt Snapinn | Cain |
| 189 | The Beast's Revenge | comic story | 7 | script: John Albano; pencils: MW Kaluta; inks: MW Kaluta; letters: John Costanza | Cain (host); John; Margaret |
| 190 | The Secret of Camp Galaxy | comic story | 7.67 | pencils: Bob Brown; inks: Bob Brown; letters: Gaspar Saladino | Cain (host); Johnny Thornton; Mr. Nairam; Vorkle; Thboothga; Uncle Y'Tram; Zeba; Orgaal; Svardo |
| 191 | The Forbidden Wish | comic story | 4 | pencils: George Roussos; inks: George Roussos | Cain (host); Cal Colby; Helen |
| 192 | The Lunatic | comic story | 5 | script: Jack Oleck; pencils: Ralph Reese; inks: Ralph Reese; letters: John Costanza | Cain (host); Aaron Edwards; Peter Edwards |
| 193 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 194 | A Breath of Black Death | comic story | 11 | script: Francis X. Bushmaster; pencils: Tony DeZuniga; inks: Tony DeZuniga; letters: John Costanza | Terron; Tatuk |
| 195 | Slogging Through the Swamp on a Murky Evening | comic story | 1 | script: Len Wein; pencils: Joe Orlando, Sal Amendola; inks: Joe Orlando, Sal Amendola; letters: Ben Oda | |
| 196 | Complete Your Collection with These Other Silver and Bronze Age Omnibuses | insert or dust jacket | 0 | pencils: Karl Kerschl; inks: Karl Kerschl | Swamp Thing [Alec Holland]; Batgirl [Barbara Gordon]; Batman [Bruce Wayne]; Wonder Woman [Diana Prince]; Teen Titans [Robin [Dick Grayson]; Kid Flash [Wally West]; Aqualad [Garth]; Wonder Girl [Donna Troy]; Speedy [Roy Harper]; Mal Duncan; Bumblebee [Karen Beecher]] |
| 197 | Back Cover | illustration | 1 | pencils: Neal Adams, Gil Kane; inks: Neal Adams, Wally Wood | |
| 198 | Spine of Book | insert or dust jacket | 0 | pencils: Joe Orlando; inks: Joe Orlando | Cain |