| 0 | - | cover | 1 | pencils: Glenn Fabry; inks: Glenn Fabry; colors: Ryan Brown | |
| 1 | Foreword | foreword, introduction, preface, afterword | 2 | script: Eric Kripke | |
| 2 | - | cover reprint (on interior page) | 1 | pencils: Glenn Fabry; inks: Glenn Fabry; colors: Ryan Brown | |
| 3 | Better Living through Chemistry | comic story | 22 | script: Eric Kripke; pencils: John Higgins; inks: John Higgins; colors: John Higgins; letters: Clem Robins | |
| 4 | - | cover reprint (on interior page) | 1 | pencils: Glenn Fabry; inks: Glenn Fabry; colors: Ryan Brown | |
| 5 | Part II: Hero Trip | comic story | 22 | script: Eric Kripke; pencils: John Higgins; inks: John Higgins; colors: John Higgins; letters: Clem Robins | |
| 6 | - | cover reprint (on interior page) | 1 | pencils: Glenn Fabry; inks: Glenn Fabry; colors: Ryan Brown | |
| 7 | Part III: Chasing the Dragon | comic story | 22 | script: Eric Kripke; pencils: John Higgins; inks: John Higgins; colors: SotoColor; letters: Clem Robins | |
| 8 | - | cover reprint (on interior page) | 1 | pencils: Glenn Fabry; inks: Glenn Fabry; colors: Ryan Brown | |
| 9 | Part IV: Rock Bottom | comic story | 22 | script: Eric Kripke; pencils: John Higgins, Marc Olivent; inks: John Higgins, Marc Olivent; colors: SotoColor; letters: Clem Robins | |
| 10 | - | cover reprint (on interior page) | 1 | pencils: Glenn Fabry; inks: Glenn Fabry; colors: Ryan Brown | |
| 11 | Part V: Journey to the Center of the Mind | comic story | 22 | script: Eric Kripke; pencils: John Higgins, Marc Olivent; inks: John Higgins, Marc Olivent; colors: SotoColor; letters: Clem Robins | |
| 12 | - | cover reprint (on interior page) | 1 | pencils: Glenn Fabry; inks: Glenn Fabry; colors: Ryan Brown | |
| 13 | Part VI: The Comedown | comic story | 22 | script: Eric Kripke; pencils: John Higgins; inks: John Higgins; colors: SotoColor; letters: Clem Robins | |