| 0 | Closed -- No One Dies Today! | cover | 1 | pencils: Nick Cardy; inks: Nick Cardy; colors: Alex Sinclair; letters: Nick Cardy | |
| 1 | Table of Contents | table of contents | 5 | letters: typeset | |
| 2 | House of Mystery #195 | cover reprint (on interior page) | 1 | pencils: Bernie Wrightson; inks: Bernie Wrightson | |
| 3 | Welcome to the House of Mystery! | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Sergio Aragonés; inks: Sergio Aragonés | Cain (host); Gregory the Gargoyle |
| 4 | Bat Out of Hell | comic story | 8 | script: Jack Oleck; pencils: Nestor Redondo; inks: Nestor Redondo | Cain (host); Adam Leach |
| 5 | The Fantastic Wishing Well | comic story | 5.67 | pencils: Mort Meskin; inks: George Roussos, Mort Meskin; letters: Artie Simek | Brad Horton |
| 6 | - | cartoon | 2 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | Cain |
| 7 | Countdown! | comic story | 3 | pencils: Ralph Reese; inks: Ralph Reese; letters: Milt Snapinn | Cain (host); Jason; Valerie; Peter |
| 8 | Things Old... Things Forgotten | comic story | 10 | pencils: Bernie Wrightson; inks: Bernie Wrightson; letters: Ben Oda | Cain (host); Igor Lazlo; Gork; Eric Roder; Hans |
| 9 | Who Am I? | comic story | 6 | pencils: Bernard Baily; inks: Bernard Baily | |
| 10 | Trick or Treat | comic story | 1.5 | pencils: Mike Kaluta; inks: Mike Kaluta; letters: Ray Holloway | |
| 11 | House of Mystery #196 | cover reprint (on interior page) | 1 | pencils: Tony DeZuniga; inks: Tony DeZuniga | |
| 12 | A Girl and Her Dog! | comic story | 9 | script: Gerry Conway; pencils: Gray Morrow; inks: Gray Morrow; letters: John Costanza | Cain (host); Peter (dog); Michael; Lissa; Miss Cruthers |
| 13 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 14 | The Alien within Me | comic story | 8 | pencils: Alex Toth; inks: Alex Toth; letters: Stan Starkman | Professor Vraney; Professor Adams |
| 15 | Child of the Dead | comic story | 2 | script: Jack Oleck; pencils: Wayne Howard; inks: Wayne Howard | Cain (host); Walter Scott |
| 16 | Cain's Room 13 | cartoon | 1 | script: Lore Shoberg; pencils: Lore Shoberg; inks: Lore Shoberg | Cain |
| 17 | Dark Journey | comic story | 6 | pencils: Nick Cardy; inks: Nick Cardy; letters: Pat Gordon | |
| 18 | My Heart Becomes So Icy Cold | comic story | 1 | script: Len Wein; pencils: Tony DeZuniga; inks: Tony DeZuniga; letters: Ben Oda | |
| 19 | The Little People! | comic story | 10 | script: Jack Oleck; pencils: Gil Kane; inks: Frank Giacoia; letters: Milt Snapinn | Cain (host); Michael O'Bannion |
| 20 | House of Mystery #197 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams | |
| 21 | Ghost Ship | comic story | 12.5 | script: Jack Oleck; pencils: Jack Sparling; inks: Jack Sparling | Cain (host); John Dodson; Jamie; Captain Jonah Frame; Fenton |
| 22 | Mr. Mortem! | comic story | 5.67 | pencils: Leonard Starr; inks: Leonard Starr | Vera; Drew Wilson; Conrad Wilson; Mr. Mortem; Biff Saunders |
| 23 | I Wish I May, Wish I Might | comic story | 3.5 | script: Len Wein; pencils: Dick Dillin; inks: Frank Giacoia; letters: Charlotte Jetter | Mark Wagner; Genie |
| 24 | - | cartoon | 1 | script: Lore Shoberg; pencils: Lore Shoberg; inks: Lore Shoberg | |
| 25 | House of Horrors | comic story | 8 | script: Jack Oleck; pencils: Nestor Redondo; inks: Nestor Redondo | Cain (host); Frank Cannon; Anna Vargas; Catherine Vargas; Jan Vargas |
| 26 | The Guardian of the Past | comic story | 6 | pencils: Nick Cardy; inks: Nick Cardy; letters: Pat Gordon | Mr. Haver; Orab; Gamel; Rami |
| 27 | House of Mystery #198 | cover reprint (on interior page) | 1 | pencils: Nick Cardy; inks: Nick Cardy | |
| 28 | Two Lives to Live! | comic story | 12 | script: Jack Oleck; pencils: Mike Sekowsky; inks: Nick Cardy | Cain (host); Ian Lerner; Satan; Luisa |
| 29 | - | cartoon | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 30 | He Adopted a Martian Boy | comic story | 6 | pencils: Bernard Baily; inks: Bernard Baily | Cain (host); Fred Marshal; Akza |
| 31 | Brief Visit | comic story | 4 | script: Sam Glanzman; pencils: Sam Glanzman; inks: Sam Glanzman; letters: Sam Glanzman | Cain (host); Satan; Nilats (demon); Itepal (demon); Reltih (demon) |
| 32 | Cain's Room 13 | cartoon | 1 | script: Lore Shoberg; pencils: Lore Shoberg; inks: Lore Shoberg | Cain |
| 33 | The Day of the Demon! | comic story | 8 | script: Archie Goodwin; pencils: Mike Sekowsky; inks: Carl Anderson; letters: Ben Oda | Cain (host); Mordok; Gustav Tablun; Peter Kurt; Erica; Stefan |
| 34 | The Thing in the Telescope | comic story | 6 | pencils: Mort Meskin; inks: Mort Meskin | Detective-Lieutenant John Hollis; Oswald Freems; Willy; Jack |
| 35 | House of Mystery #199 | cover reprint (on interior page) | 1 | pencils: Neal Adams; inks: Neal Adams | |
| 36 | Sno' Fun! | comic story | 9 | script: Sergio Aragonés; pencils: Wally Wood; inks: Wally Wood; letters: John Costanza | Cain (story host); Gregory (gargoyle); Dr. Wallace B. Peterson (scientist); Professor Strauss (scientist) |
| 37 | - | cartoon | 1 | pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 38 | He Doomed the World! | comic story | 8 | pencils: Jack Kirby; inks: Jack Kirby; letters: Pat Gordon | Cain (host); Frank Cable; Mr. Hiller; Mr. Lollar; Mr. Carlson; Mr. Hogarth |
| 39 | - | cartoon | 1 | pencils: Sergio Aragonés; inks: Sergio Aragonés | Cain; Gregory |
| 40 | Snow Beast | comic story | 8 | script: Lynn Marron; pencils: Rich Buckler; inks: Rich Buckler; letters: John Costanza | Cain (host); Kirk; Sam; Nita; Su-Ka-Tae (Abominable Snowman) |
| 41 | The Whole Ball of Tin | comic story | 7 | script: Gerry Conway, Len Wein; pencils: Bob Oksner; inks: Bob Oksner; letters: John Costanza | Cain (host); Wilson Brown; J. Frederic Brown |
| 42 | The Haunting Wind! | comic story | 4 | script: Jack Miller; pencils: John Giunta; inks: John Giunta; letters: Gaspar Saladino | Cain (host); Dan Russell; Jim Nelson |
| 43 | House of Mystery #200 | cover reprint (on interior page) | 1 | pencils: Mike Kaluta; inks: Mike Kaluta | |
| 44 | House of Mystery | foreword, introduction, preface, afterword | 1 | script: Len Wein; pencils: Mike Kaluta; inks: Mike Kaluta; letters: Milt Snapinn | Cain |
| 45 | The Beast's Revenge | comic story | 7 | script: John Albano; pencils: Mike Kaluta; inks: Mike Kaluta; letters: John Costanza | Cain (host); John; Margaret |
| 46 | The Secret of Camp Galaxy | comic story | 7.5 | pencils: Bob Brown; inks: Bob Brown; letters: Gaspar Saladino | Cain (host); Johnny Thornton; Mr. Nairam; Vorkle; Thboothga; Uncle Y'Tram; Zeba; Orgaal; Svardo |
| 47 | The Forbidden Wish | comic story | 4 | pencils: George Roussos; inks: George Roussos | Cain (host); Cal Colby; Helen |
| 48 | The Lunatic | comic story | 5 | script: Jack Oleck; pencils: Ralph Reese; inks: Ralph Reese | Cain (host); Aaron Edwards; Peter Edwards |
| 49 | - | cartoon | 1 | pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 50 | A Breath of Black Death | comic story | 11 | script: Francis X. Bushmaster; pencils: Tony DeZuniga; inks: Tony DeZuniga | Terron; Tatuk |
| 51 | Slogging through the Swamp on a Murky Evening | comic story | 1 | script: Len Wein; pencils: Joe Orlando, Sal Amendola; inks: Joe Orlando, Sal Amendola; letters: Ben Oda | |
| 52 | House of Mystery #201 | cover reprint (on interior page) | 1 | pencils: Mike Kaluta; inks: Mike Kaluta | |
| 53 | House of Mystery | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Bernie Wrightson; inks: Bernie Wrightson | Cain; Frankenstein monster |
| 54 | Put Your Trust in a Killer! | comic story | 8 | script: Steve Skeates; pencils: Adolfo Buylla; inks: Adolfo Buylla | Cain (host); George Ringler; Julie Ringler; Big Joe |
| 55 | Million-Dollar Magic | comic story | 6 | pencils: Bernard Baily; inks: Bernard Baily | Cain (host); Caspar Creed; Jenkins; James Wood |
| 56 | - | cartoon | 1 | pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 57 | Hail the Conquering Aliens | comic story | 8 | pencils: Ruben Moreira; inks: Ruben Moreira | Cain (host); Dan Welks; Hal; Mayor Plover; Betty Sears; Colonel Bear |
| 58 | The Demon Within! | comic story | 7 | script: Joe Orlando, John Albano; pencils: Jim Aparo; inks: Jim Aparo; letters: Jim Aparo | Cain (host); Gary Winters (boy who can become a monster); Gary Winters (Gary's father); Kathy Winters (Gary's sister); Mildred Winters (Gary's mother) |
| 59 | A Tale of Vengeance! | comic story | 7 | script: John Albano; pencils: Sam Glanzman; inks: Sam Glanzman; letters: Sam Glanzman | Cain (host); Chet Yovac; Whitney Claymore |
| 60 | House of Mystery #202 | cover reprint (on interior page) | 1 | pencils: Mike Kaluta; inks: Mike Kaluta | |
| 61 | House of Mystery | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Mike Kaluta; inks: Mike Kaluta | Cain |
| 62 | The Shearing of a Soul! | comic story | 7 | script: Gerry Conway; pencils: Mike Sekowsky; inks: Frank Giacoia | Cain (host); Carson Shrew; Milly Crochet; Abner; Ellen; Jubal |
| 63 | A Deal with a Sorcerer! | comic story | 7 | script: John Albano; pencils: Nestor Redondo; inks: Nestor Redondo | Cain (host); Franklin Owen; Urbain; Mr. Gaufridi |
| 64 | Stay Away from Me -- You Might Die | comic story | 7.67 | pencils: Gene Colan; inks: Gene Colan | Cain (host); Dr. Bertrand; Charles |
| 65 | Trick or Treat | comic story | 1.5 | pencils: Sid Greene; inks: Sid Greene | Adolf Hitler |
| 66 | The Poster Plague! | comic story | 7 | script: Steve Skeates; pencils: Sergio Aragonés; inks: Sergio Aragonés | Cain (host); Warren; Debbie |
| 67 | The Phantom on Wheels! | comic story | 6 | pencils: John Prentice; inks: John Prentice; letters: Ben Oda | Cain (host); Ted Perry; Mr. Denning; Murdock the Magician; Mr. White |
| 68 | House of Mystery #203 | cover reprint (on interior page) | 1 | pencils: Russ Heath; inks: Russ Heath | |
| 69 | House of Mystery | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Bernie Wrightson; inks: Bernie Wrightson | Cain |
| 70 | The 1000 Eyes of Death | comic story | 10 | script: Robert Kanigher; pencils: Ernie Chua; inks: Ernie Chua | Mark Dawson; Bear Claw |
| 71 | - | cartoon | 1 | pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 72 | The Golden Doom | comic story | 6 | pencils: Nick Cardy; inks: Nick Cardy | Cain (host); Emile Marlez; Dr. Devin |
| 73 | Almost Human | comic story | 7 | script: John Albano; pencils: Jack Sparling; inks: Jack Sparling | Cain (host); Donald Morrison; Mary Morrison; Al; Pop |
| 74 | - | cartoon | 1 | pencils: John Albano; inks: John Albano | |
| 75 | The Tower of Prey | comic story | 11 | pencils: Nestor Redondo; inks: Nestor Redondo | Cain (host); J. J. Rahtlar; Mary Q. Lardley |
| 76 | House of Mystery #204 | cover reprint (on interior page) | 1 | pencils: Bernie Wrightson; inks: Bernie Wrightson | |
| 77 | All in the Family... | comic story | 9 | script: Virgil North, Bernie Wrightson; pencils: Bernie Wrightson; inks: Bernie Wrightson | Cain (host); Mary; Fred; Gloria |
| 78 | - | cartoon | 1 | pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 79 | Realm of the Mystics | illustration | 1 | pencils: Jack Sparling; inks: Jack Sparling; letters: John Costanza | |
| 80 | Never Deal with a Demon | comic story | 3 | script: Jack Oleck; pencils: Win Mortimer; inks: Win Mortimer | Cooper |
| 81 | To Die for Magda! | comic story | 10 | script: Carl Wessler; pencils: Alex Niño; inks: Alex Niño | Cain (host); Stephan Tiza; Magda Kossu; Janos Kossu; Mr. Kossu |
| 82 | House of Mystery #205 | cover reprint (on interior page) | 1 | pencils: Jack Sparling; inks: Jack Sparling | |
| 83 | House of Mystery | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Bernie Wrightson; inks: Bernie Wrightson | Cain |
| 84 | The Coffin Creature | comic story | 10 | script: Jack Sparling, Michael Fleisher; pencils: Jack Sparling; inks: Jack Sparling | Stinky; The Coffin Creature; Pierre; Claude La Plat |
| 85 | Phony Face! | comic story | 5 | script: E. Nelson Bridwell; pencils: Gerry Talaoc; inks: Gerry Talaoc | Cain (host); Grant Weymore; Dr. Magog |
| 86 | - | cartoon | 1 | pencils: John Albano; inks: John Albano | |
| 87 | Over the High Side | comic story | 7 | script: Lore Shoberg; pencils: Alan Weiss; inks: Ralph Reese | Cain (host); Dave the Buck; Beelzebub |
| 88 | House of Mystery #206 | cover reprint (on interior page) | 1 | pencils: Tony DeZuniga; inks: Tony DeZuniga | |
| 89 | House of Mystery | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Bernie Wrightson; inks: Bernie Wrightson; letters: Ben Oda | Cain |
| 90 | Sentimental Journey | comic story | 6 | script: Jack Oleck; pencils: Bill Payne; inks: Bill Payne; letters: John Costanza | Cain (host); Aunt Aggie; Dana |
| 91 | Beastly Funny | cartoon | 1 | script: Lore Shoberg; pencils: Lore Shoberg; inks: Lore Shoberg | |
| 92 | The Burning! | comic story | 8 | script: Jack Oleck; pencils: Mike Sekowsky; inks: Tom Palmer; letters: John Costanza | Cain (host); Meg Cooper (witch); Adam Strat |
| 93 | A Real Mother! | comic story | 8 | script: Virgil Redondo; pencils: Ernesto Patricio; inks: Ernesto Patricio | Cain (host); Lester; Muriel; Jack |
| 94 | House of Mystery #207 | cover reprint (on interior page) | 1 | pencils: Bernie Wrightson; inks: Bernie Wrightson | |
| 95 | House of Mystery | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Bernie Wrightson; inks: Bernie Wrightson | Cain; Gregory |
| 96 | Last Ritual Last Rites | comic story | 10 | script: Bill Meredith; pencils: Bill Payne; inks: Bill Payne | Cain (host); Bennett Renier; Charlotte Renier; Hillory; Amrita |
| 97 | - | cartoon | 1 | pencils: John Albano; inks: John Albano | |
| 98 | The Spell! | comic story | 2 | pencils: Jim Starlin; inks: Dan Adkins | Cain (host); Ol' Nell |
| 99 | Cain's Rumpus Room | cartoon | 1 | script: Joe Schenkman; pencils: Joe Schenkman; inks: Joe Schenkman; letters: Joe Schenkman | |
| 100 | This Evil Demon Loves People! | comic story | 9 | script: Sheldon Mayer; pencils: Jack Sparling; inks: Jack Sparling | Cain (host); Alex Garvey; Geoffry Garvey; Mrs. Cooney; Miss Schermerhorn; Hilda Garvey |
| 101 | House of Mystery #208 | cover reprint (on interior page) | 1 | pencils: Nick Cardy; inks: Nick Cardy | |
| 102 | The Creator of Evil! | comic story | 12 | script: John Albano; pencils: E. R. Cruz; inks: E. R. Cruz | Cain (host); Fred; Judge Wheatly; Phil Butler; Leonard Martin; Robert Albertson; Boris Illytch; Professor Phi; John Curry; Doris Edmond |
| 103 | The Day the Clock Stopped? | comic story | 10 | script: Robert Kanigher; pencils: Ruben Yandoc; inks: Ruben Yandoc | Cain (host); Adam Sneal; Robert; Kinderger; Nick Roma |
| 104 | - | cartoon | 1 | pencils: Sergio Aragonés; inks: Sergio Aragonés | Gregory |
| 105 | - | cartoon | 0.5 | pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 106 | House of Mystery #209 | cover reprint (on interior page) | 1 | pencils: Bernie Wrightson; inks: Bernie Wrightson | |
| 107 | House of Mystery | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Bernie Wrightson; inks: Bernie Wrightson | Cain |
| 108 | For Money... For Love! | comic story | 8 | script: Steve Skeates; pencils: Alfredo Alcala; inks: Alfredo Alcala; letters: Alfredo Alcala | Cain (host); John; Mr. Lawson; Mary Lawson; Aaron Milford |
| 109 | - | cartoon | 0.5 | script: Bill Riley; pencils: Bill Riley; inks: Bill Riley; letters: Bill Riley | |
| 110 | Maniacs | comic story | 8 | script: Steve Skeates; pencils: Ruben Yandoc; inks: Ruben Yandoc | Cain (host); Myra; Michael O'Donoghue |
| 111 | Tomorrow I Hang! | comic story | 5 | script: E. Nelson Bridwell; pencils: Jim Aparo; inks: Jim Aparo; letters: Jim Aparo | Cain (host); Mario; Viola |
| 112 | House of Mystery #210 | cover reprint (on interior page) | 1 | pencils: Mike Kaluta; inks: Mike Kaluta | |
| 113 | The Exterminator | comic story | 8 | script: Michael Fleisher, Maxene Fabe; pencils: Rudy Nebres; inks: Rudy Nebres | Cain (host); Frank Alban; Rita; Mrs. Latrodectus |
| 114 | - | cartoon | 1 | pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 115 | The Immortal | comic story | 6 | script: Jack Oleck; pencils: Gerry Talaoc; inks: Gerry Talaoc | Cain (host); Cassandro; Marco Polo |
| 116 | Body Beautiful | comic story | 8 | script: Jack Oleck; pencils: José Delbo; inks: José Delbo | Cain (host); John Bannister; Martha Bannister; Anne |
| 117 | House of Mystery #211 | cover reprint (on interior page) | 1 | pencils: Bernie Wrightson; inks: Bernie Wrightson | |
| 118 | House of Mystery | foreword, introduction, preface, afterword | 1 | script: Joe Orlando; pencils: Bernie Wrightson; inks: Bernie Wrightson | Cain |
| 119 | Deliver Us from Evil | comic story | 10 | script: Jack Oleck; pencils: Nestor Redondo; inks: Nestor Redondo | Cain (host); Emile Dravos; Peter Janos; Maria Dravos |
| 120 | - | cartoon | 1 | pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 121 | Money to Burn | comic story | 3 | script: Jack Oleck; pencils: Dan Green; inks: Dan Green | Cain (host); John Avery |
| 122 | Unholy Change! | comic story | 8 | script: Sheldon Mayer; pencils: Gerry Talaoc; inks: Gerry Talaoc | Cain (host); George Farson; Freda; Mr. Perkins; Detective Sergeant Sloan; Marge |