| 0 | - | cover | 1 | pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig | Supergirl [Kara Zor-El] |
| 1 | - | cover reprint (on interior page) | 1 | pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig | Supergirl [Kara Zor-El] |
| 2 | Part One | comic story | 20 | script: Michael Green, Mike Johnson; pencils: Mahmud Asrar; inks: Dan Green, Mahmud Asrar; colors: Dave McCaig; letters: John J. Hill | Supergirl [Kara Zor-El]; Superman [Clark Kent; Kal-El] |
| 3 | - | cover reprint (on interior page) | 1 | pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig | Supergirl [Kara Zor-El]; Superman [Clark Kent; Kal-El] |
| 4 | Part Two | comic story | 20 | script: Michael Green, Mike Johnson; pencils: Mahmud Asrar; inks: Dan Green; colors: Dave McCaig; letters: John J. Hill | Supergirl [Kara Zor-El]; Superman [Clark Kent; Kal-El]; Miss Thorn |
| 5 | - | cover reprint (on interior page) | 1 | pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig | Supergirl [Kara Zor-El] |
| 6 | Part Three | comic story | 20 | script: Michael Green, Mike Johnson; pencils: Mahmud Asrar; inks: Bill Reinhold; colors: Paul Mounts; letters: Rob Leigh | Supergirl [Kara Zor-El]; Superman [Clark Kent; Kal-El]; Jor-El (cameo flashback); Lara (cameo flashback); Simon Tycho; Miss Thorn; The Brain |
| 7 | - | cover reprint (on interior page) | 1 | pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig | Supergirl [Kara Zor-El]; Superman [Clark Kent; Kal-El]; The Brain |
| 8 | Part Four | comic story | 20 | script: Michael Green, Mike Johnson; pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig; letters: Rob Leigh | Supergirl [Kara Zor-El]; Mr. Henderson; Mr. Jacobs (death); Simon Tycho; Miss Thorn; The Brain |
| 9 | - | cover reprint (on interior page) | 1 | pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig | Supergirl [Kara Zor-El]; Reign |
| 10 | Part Five | comic story | 20 | script: Michael Green, Mike Johnson; pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig; letters: Rob Leigh | Supergirl [Kara Zor-El]; Reign; Zor-El (hologram) |
| 11 | - | cover reprint (on interior page) | 1 | pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig | Supergirl [Kara Zor-El] |
| 12 | Part Six | comic story | 20 | script: Michael Green, Mike Johnson; pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig; letters: Rob Leigh | Supergirl [Kara Zor-El]; Zor-El (flashback); Alura (hallucination); Reign (villain) |
| 13 | - | cover reprint (on interior page) | 1 | pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig | Supergirl [Kara Zor-El]; Worldkillers [Deimax; Flower of Heaven; Perrilus; Reign] |
| 14 | Part Seven | comic story | 20 | script: Michael Green, Mike Johnson; pencils: Mahmud Asrar; inks: Mahmud Asrar; colors: Dave McCaig; letters: Rob Leigh | Supergirl [Kara Zor-El]; Worldkillers [Deimax; Flower of Heaven; Perrilus; Reign] |
| 15 | Supergirl Character Designs | illustration | 3 | pencils: Jim Lee, Mahmud Asrar; inks: Jim Lee, Mahmud Asrar; colors: Jim Lee, Mahmud Asrar | |
| 16 | Issue #6 Unused Cover by Mahmud Asrar | illustration | 1 | pencils: Mahmud Asrar; inks: Mahmud Asrar | |