| 0 | - | cover | 1 | pencils: Duncan Rouleau; inks: Marlo Alquiza; colors: Tanya Horie, Richard Horie | Superman; The Atom [Ray Palmer]; Supergirl [Matrix; Linda Danvers]; Superboy [Kon-El] |
| 1 | Superman: Critical Condition | illustration | 1 | | |
| 2 | Superman: Critical Condition | credits, title page | 3 | pencils: Duncan Rouleau; inks: Marlo Alquiza; colors: Tanya Horie, Richard Horie | Superman; The Atom [Ray Palmer]; Supergirl [Matrix; Linda Danvers]; Superboy [Kon-El] |
| 3 | Cast of Characters | character profile | 2 | pencils: Pablo Raimondi, Doug Mahnke, Carlo Barberi, Duncan Rouleau; inks: Tom Nguyen, Juan Vlasco, Danny Miki, Jaime Mendoza, José Marzán Jr. | Superman; Lois Lane; Lex Luthor; Batman; Steel [John Henry Irons]; Superboy [Kon-El]; Supergirl [Matrix; Linda Danvers]; The Atom [Ray Palmer]; Deathstroke; La Encantadora |
| 4 | Pranked! | comic story | 22 | script: J. M. DeMatteis; pencils: Mike McKone; inks: Marlo Alquiza; colors: Glenn Whitmore, Wildstorm FX; letters: Bill Oakley | Superman [Clark Kent; Kal-El]; Jimmy Olsen; Ron Troupe; Lucy Lane; Adversary [Cary Richards]; Prankster [Oswald Loomis]; Lex Luthor |
| 5 | All Fall Down | comic story | 22 | script: Mark Schultz; pencils: Pablo Raimondi; inks: José Marzán Jr.; colors: Wildstorm FX; letters: Ken Lopez | Superman; John Henry Irons; Natasha Irons; Kelex; Lex Luthor; Hope; Mercy; Batman; Boris |
| 6 | Metropolica | comic story | 22 | script: Joe Kelly; pencils: Pascual Ferry; inks: Álvaro López; colors: Tom McCraw, Digital Chameleon; letters: Comicraft | Superman [Clark Kent; Kal-El]; Hope; Mercy; Lex Luthor; Jimmy Olsen; Bibbo Bibbowksi; Mr. Wilkins |
| 7 | D.O.A. | comic story | 22 | script: Joe Kelly; pencils: Cary Nord; inks: Jason Baumgartner; colors: Wildstorm FX; letters: Comicraft | Superman; Batman; Lois Lane; Mikalia "Mike" Shepard |
| 8 | Critical Condition, Part One: Little Big Man | comic story | 22 | script: Jeph Loeb; pencils: Duncan Rouleau; inks: Jaime Mendoza; colors: Tanya Horie, Richard Horie; letters: Richard Starkings | Superman [Clark Kent; Kal-El]; Superboy [Kon-El]; Supergirl [Matrix; Linda Danvers]; Steel [John Henry Irons]; The Atom [Ray Palmer]; Lois Lane; Jimmy Olsen; Dr. Sarah Charles; Dr. Kitty Faulkner; Prof. Bridgette Crosby; Lex Luthor; Mercy; The Prankster [Oswald Loomis; as Steel] |
| 9 | Critical Condition, Part Two of Four: Green Universe | comic story | 22 | script: J. M. DeMatteis; pencils: Carlo Barberi; inks: Juan Vlasco; colors: Wildstorm FX; letters: Bill Oakley | Superman [Clark Kent; Kal-El]; Superboy [Kon-El]; Supergirl [Matrix; Linda Danvers]; Steel [John Henry Irons]; The Atom [Ray Palmer]; Lois Lane; Jimmy Olsen; Perry White; Dr. Sarah Charles; Dr. Kitty Faulkner; Deathstroke [Slade Wilson]; La Encantadora; The Prankster [Oswald Loomis; as Steel]; Jonat |
| 10 | Critical Condition, Part Three of Four: Inside Superman | comic story | 22 | script: Mark Schultz; pencils: Doug Mahnke; inks: Tom Nguyen; colors: Wildstorm FX; letters: Ken Lopez | Superman; Steel [John Henry Irons]; Natasha Irons; Supergirl [Matrix; Linda Danvers]; Superboy [Kon-El]; Lois Lane; Deathstroke; La Encantadora; The Atom [Ray Palmer]; The Prankster [Oswald Loomis; as Steel]; Dr. Sarah Charles; Dr. Kitty Faulkner; Prof. Bridgette Crosby |
| 11 | Critical Condition, Part Four: Death's Door | comic story | 22 | script: Joe Kelly; pencils: Kano; inks: Marlo Alquiza; colors: Wildstorm FX; letters: Comicraft | Superman [Clark Kent; Kal-El]; Steel [John Henry Irons]; Superboy [Kon-El]; Supergirl [Matrix; Linda Danvers]; The Atom [Ray Palmer]; Dr. Sarah Charles; Dr. Kitty Faulkner; Prof. Bridgette Crosby; Jimmy Olsen; Deathstroke; La Encantadora; The Prankster [Oswald Loomis; as Steel] |
| 12 | Cover Gallery | cover reprint (on interior page) | 7 | pencils: Mike McKone, Doug Mahnke, Ian Churchill; inks: Marlo Alquiza, Tom Nguyen, Norm Rapmund, Cam Smith, Danny Miki, Mark Schultz | Superman; The Prankster [Oswald Loomis; as Steel] (also as jack-in-the-box); Batman; Supergirl [Matrix; Linda Danvers]; Superboy [Kon-El]; Deathstroke; Steel [John Henry Irons] |
| 13 | - | promo (ad from the publisher) | 1 | pencils: Duncan Rouleau; inks: Marlo Alquiza | Superman; Supergirl [Matrix; Linda Danvers]; Superboy [Kon-El]; The Prankster [Oswald Loomis; as Steel] |