| 0 | Misery in Space! | cover | 1 | pencils: John Delaney; inks: Mike Manley | Superman; Lobo |
| 1 | - | blank page(s) | 1 | | |
| 2 | - | credits, title page | 4 | letters: typeset | Superman |
| 3 | Is There a Doctor in the House? | cover reprint (on interior page) | 1 | pencils: Bret Blevins; inks: Terry Austin; colors: Marie Severin; letters: Todd Klein | Superman; Lois Lane; Lex Luthor |
| 4 | The War Within [Part 1] | comic story | 22 | script: Scott McCloud; pencils: Rick Burchett; inks: Terry Austin; colors: Marie Severin; letters: Lois Buhalis | Superman; Lois Lane |
| 5 | Under Enemy Fire! | cover reprint (on interior page) | 1 | pencils: Bret Blevins; inks: Terry Austin; colors: Marie Severin; letters: Todd Klein | Lois Lane |
| 6 | The War Within [Part 2] | comic story | 22 | script: Scott McCloud; pencils: Rick Burchett; inks: Terry Austin; colors: Marie Severin; letters: Lois Buhalis | Superman; Lois Lane |
| 7 | Strange Sports Stories! | cover reprint (on interior page) | 1 | pencils: Bret Blevins; inks: Terry Austin; letters: Todd Klein | Superman |
| 8 | Grand Slam | comic story | 22 | script: Scott McCloud; pencils: Rick Burchett; inks: Terry Austin; colors: Tom Ziuko; letters: Lois Buhalis | Superman; Lois Lane; Professor Hamilton; Lobo (cameo) |
| 9 | - | cover | 1 | pencils: Rick Burchett; inks: Terry Austin; colors: Marie Severin | Superman |
| 10 | Stop the Presses! | comic story | 22 | script: Mark Evanier; pencils: Neil Vokes; inks: Terry Austin; colors: Marie Severin; letters: Lois Buhalis | Superman; Lois Lane |
| 11 | - | cover reprint (on interior page) | 1 | pencils: Joe Staton; inks: Terry Austin; letters: Todd Klein | Akamin (monster); Superman; Zatara; Lois Lane |
| 12 | Dark Planes Drifter | comic story | 54 | script: Hilary J. Bader; pencils: Joe Staton; inks: Dan Davis; colors: Tom Ziuko; letters: Albert De Guzman | Superman; Lois Lane; Jimmy Olsen; Zatara; Dr. Fate; Akamin (monster) |
| 13 | Bibbo Blows It! | cover | 1 | pencils: Rick Burchett; inks: Terry Austin; colors: Marie Severin; letters: Todd Klein | Superman; Bibbo |
| 14 | Maximum Effort! | comic story | 22 | script: Mark Evanier; pencils: Rick Burchett; inks: Terry Austin; colors: Rick Taylor; letters: Lois Buhalis | Superman; Bibbo |
| 15 | The Fall of Clark Kent! | cover reprint (on interior page) | 1 | pencils: Rick Burchett; inks: Terry Austin | Superman; Clark Kent |
| 16 | Clark Kent, You're a Nobody! | comic story | 22 | script: Mark Millar; pencils: Aluir Amâncio; inks: Terry Austin; colors: Rick Taylor; letters: Lois Buhalis | Superman |
| 17 | Misery in Space! | cover reprint (on interior page) | 1 | pencils: John Delaney; inks: Mike Manley | Superman; Lobo |
| 18 | Misery in Space! | comic story | 40 | script: David Michelinie; pencils: John Delaney; inks: Mike Manley; colors: Stuart Chaifetz; letters: Janice Chiang | Superman; Lobo; Professor Hamilton; Lois Lane; Squeed |
| 19 | - | promo (ad from the publisher) | 1 | letters: typeset | Superman |
| 20 | - | promo (ad from the publisher) | 1 | letters: typeset | Superman; Batman |
| 21 | - | blank page(s) | 1 | | |
| 23 | - | promo (ad from the publisher) | 1 | letters: typeset | Superman |