| 0 | - | cover | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | |
| 1 | - | blank page(s) | 3 | | |
| 2 | Superman / Batman: Public Enemies | credits, title page | 1 | letters: typeset | |
| 3 | Superman / Batman: Public Enemies | credits, title page | 2 | letters: typeset | |
| 4 | When Clark Met Bruce | comic story | 2 | script: Jeph Loeb; pencils: Tim Sale; inks: Tim Sale; colors: Mark Chiarello; letters: Richard Starkings | Pete Ross; Clark Kent; Bruce Wayne; Alfred Pennyworth |
| 5 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | Superman; Batman |
| 6 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | Batman; Superman |
| 7 | - | foreword, introduction, preface, afterword | 1 | letters: typeset | |
| 8 | Part One: World's Finest | comic story | 24 | script: Jeph Loeb; pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart; letters: Richard Starkings | Superman [Clark Kent; Kal-El]; Batman [Bruce Wayne]; Doctor Christine Gherhard (of S.T.A.R. Labs); Jonathan Kent (origin flashback); Martha Kent (origin flashback); Thomas Wayne (origin flashback); Martha Wayne (origin flashback); Metallo [John Corben] (villain); President Lex Luthor (villain); Majo |
| 9 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | Superman; Batman |
| 10 | - | foreword, introduction, preface, afterword | 1 | letters: typeset | |
| 11 | Part Two: Early Warning | comic story | 22 | script: Jeph Loeb; pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart; letters: Richard Starkings | Superman [Superman of the future; Clark Kent; Kal-El]; Batman [Bruce Wayne]; Captain Atom [Nathaniel Adam; Cameron Scott]; Alfred Pennyworth; Cat Grant; President Lex Luthor (villain) |
| 12 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | Superman; Batman |
| 13 | - | foreword, introduction, preface, afterword | 1 | letters: typeset | |
| 14 | Part Three: Running Wild | comic story | 22 | script: Jeph Loeb; pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart; letters: Richard Starkings | Superman [Clark Kent; Kal-El]; Batman [Bruce Wayne]; Captain Atom [Nathaniel Adam; Cameron Scott]; Starfire [Koriand'r; Kory Anders]; Black Lightning [Jefferson Pierce]; Katana [Tatsu Yamashiro]; Green Lantern [John Stewart]; Power Girl [Karen Starr]; Lois Lane; Vice President Pete Ross; Secretary A |
| 15 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | Superman; Batman; Hawkman; Captain Marvel |
| 16 | - | foreword, introduction, preface, afterword | 1 | letters: typeset | |
| 17 | Part Four: Battle On | comic story | 22 | script: Jeph Loeb; pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart; letters: Richard Starkings | Superman [Clark Kent; Kal-El]; Batman [Bruce Wayne]; Captain Atom [Nathaniel Adam; Cameron Scott]; Starfire [Koriand'r; Kory Anders]; Black Lightning [Jefferson Pierce]; Katana [Tatsu Yamashiro]; Green Lantern [John Stewart]; Hawkman [Carter Hall]; Captain Marvel [Billy Batson]; JSA [Justice Society |
| 18 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | Superman; Batman; Nightwing; Batgirl [Cassandra Cain]; Supergirl [Cir-El]; Robin [Tim Drake]; Superboy; Steel; Huntress; Krypto; Kelex (robot) |
| 19 | - | foreword, introduction, preface, afterword | 1 | letters: typeset | |
| 20 | Part Five: State of Siege | comic story | 22 | script: Jeph Loeb; pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart; letters: Richard Starkings | Superman [Superman of the future; Clark Kent; Kal-El; disguised as Captain Marvel]; Batman [Bruce Wayne; disguised as Hawkman]; Captain Atom [Nathaniel Adam; Cameron Scott]; Nightwing [Dick Grayson]; Batgirl [Cassandra Cain]; Supergirl [Cir-El]; Robin [Tim Drake]; Superboy [Conner Kent]; Steel [Nata |
| 21 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | Lex Luthor |
| 22 | - | foreword, introduction, preface, afterword | 1 | letters: typeset | |
| 23 | Part Six: Final Countdown | comic story | 21 | script: Jeph Loeb; pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart; letters: Richard Starkings | Superman [Clark Kent; Kal-El]; Batman [Bruce Wayne]; Captain Atom [Nathaniel Adam; Cameron Scott]; Toyman [Hiro Okamura]; Lois Lane; Perry White; Jimmy Olsen; President Lex Luthor |
| 24 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | Superman; Batman |
| 25 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | Batman; Superman |
| 26 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | |
| 27 | Sketches by Ed McGuinness | illustration | 5 | script: Ed McGuinness; pencils: Ed McGuinness; inks: Ed McGuinness; colors: Ed McGuinness; letters: Ed McGuinness | |
| 28 | Biographies | text article | 1 | letters: typeset | |
| 29 | - | blank page(s) | 3 | | |
| 30 | - | promo (ad from the publisher) | 1 | pencils: Ed McGuinness; inks: Dexter Vines; colors: Dave Stewart | |