| 0 | - | cover | 1 | pencils: Ross Andru; inks: Dick Giordano | Supergirl [Kara Zor-El]; Lesla-Lar; Lois Lane (Earth 1); Lois Lane (Earth 2); Superman [Clark Kent] (Earth 1); Superman [Clark Kent] (Earth 2); Jimmy Olsen; Tommy Jones; Lola Barnett; Harlequin [Molly Mayne] (Earth 2) |
| 1 | - | letters page | 1 | script: Bob Rozakis; pencils: Kurt Schaffenberger; inks: Kurt Schaffenberger | |
| 2 | Strangers at the Heart's Core! | comic story | 11 | script: Jack C. Harris; pencils: Win Mortimer; inks: Vince Colletta; colors: Jerry Serpe; letters: Ben Oda | Supergirl [Kara Zor-El]; Edna Danvers; Fred Danvers; Zor-El; Alura; Peter Barton; Valerie Myles; Gregory Reed; Dean Betsy Lyman; Lesla-Lar; Superboy Robot (Cameo) |
| 3 | Hostage of the Harlequin | comic story | 8 | script: E. Nelson Bridwell; pencils: Kurt Schaffenberger; inks: Dan Adkins; colors: Adrienne Roy; letters: Milt Snapinn | Superman [Clark Kent] (Earth 2); Lois Lane (Earth 2); Harlequin [Molly Mayne] (Earth 2); Smoke; Packy; Cal; Sportsmaster [Crusher Crock] (Earth 2); Green Lantern [Alan Scott] |
| 4 | A Scoop for a Snoop! | comic story | 7 | script: Bob Rozakis; pencils: John Calnan; inks: Joe Giella; colors: Jerry Serpe; letters: Shelly Leferman | Superman [Clark Kent]; Lola Barnett; Lester; Josh Coyle |
| 5 | Have You Ever Told Me the Story of My Life? | comic story | 11 | script: Marv Wolfman; pencils: Bob Oksner; inks: Vince Colletta; colors: Phil Rachelson; letters: Ben Oda | Lois Lane; Superman [Clark Kent]; The Extractor (cameo); Sam Lane (cameo); Ella Lane (cameo); Helen Gold (cameo); Marcy Lloyd (cameo); Susan Freeling (cameo); Courtney Green (cameo); Wayne Henry (cameo); Leonard Splatz (cameo); Ted Wallach |
| 6 | Open Season on Red-Headed Reporters! | comic story | 11 | script: Gerry Conway; pencils: Luis Dominguez; inks: Joe Giella; colors: Jerry Serpe; letters: Ben Oda | Jimmy Olsen; Harold (Hunter); Ted (Hunter); Perry White; Tommy Jones; Sheriff Blout; Ralph; Ted |
| 7 | - | in-house column | 0.4 | letters: typeset | |
| 8 | #69 Marv Wolfman | in-house column | 0.4 | script: Mike W. Barr | Marv Wolfman |
| 9 | - | comic story | 0.2 | script: Fred Hembeck; pencils: Fred Hembeck; inks: Fred Hembeck; letters: Fred Hembeck | Superman; Lois Lane |
| 10 | Volume 80 Issue 27 - December, 1980 | in-house column | 1 | script: Bob Rozakis | Superboy [Clark Kent]; Superman [Clark Kent]; Robin [Dick Grayson] |