| 0 | - | cover | 1 | pencils: Kenneth Rocafort; inks: Kenneth Rocafort; colors: Kenneth Rocafort | Superman; Steel [John Henry Irons]; Superboy [Kon-El]; Supergirl [Kara Zor-El]; Cyborg Superman [Hank Henshaw]; Eradicator; Doomsday |
| 1 | - | cover reprint (on interior page) | 1 | pencils: David Finch; inks: David Finch; colors: David Finch | |
| 2 | Reign of Doomsday | comic story | 51 | script: Paul Cornell; pencils: Pete Woods, Jesús Merino, Dan Jurgens, Rags Morales, Ardian Syaf, Jamal Igle; inks: Pete Woods, Jesús Merino, Norm Rapmund, Rags Morales, Ardian Syaf, Jon Sibal; colors: Blond, Brad Anderson; letters: Rob Leigh | Cyborg Superman [Hank Henshaw]; Eradicator; General Zod (flashback, cameo); Ursa (flashback, cameo); Non (flashback, cameo); Chris Kent [Lor-Zod] (flashback, cameo); Robot Lois Lane [RoboLois]; Red Lanterns (cameo); Larfleeze (cameo); Brainiac (cameo); Phantom Zone Creature (flashback) |
| 3 | - | cover reprint (on interior page) | 1 | pencils: Kenneth Rocafort; inks: Kenneth Rocafort; colors: Kenneth Rocafort | Cyborg Superman [Hank Henshaw]; Eradicator |
| 4 | Reign of the Doomsdays, Part One | comic story | 20 | script: Paul Cornell; pencils: Kenneth Rocafort, Jesús Merino; inks: Kenneth Rocafort, Jesús Merino; colors: Brad Anderson; letters: Rob Leigh | Doomsday (clones); Cyborg Superman [Hank Henshaw]; Eradicator; Doomslayer |
| 5 | - | cover reprint (on interior page) | 1 | pencils: Kenneth Rocafort; inks: Kenneth Rocafort; colors: Kenneth Rocafort | Doomsday (clones) |
| 6 | Reign of the Doomsdays, Part Two | comic story | 20 | script: Paul Cornell; pencils: Kenneth Rocafort, Axel Giménez; inks: Kenneth Rocafort, Axel Giménez; colors: Brad Anderson; letters: Rob Leigh | Doomslayer; Doomsday (clones); Cyborg Superman [Hank Henshaw]; Eradicator (corpse) |
| 7 | - | cover reprint (on interior page) | 1 | pencils: Kenneth Rocafort; inks: Kenneth Rocafort; colors: Kenneth Rocafort | Doomsday [Eradicator] |
| 8 | Reign of the Doomsdays, Part Three | comic story | 20 | script: Paul Cornell; pencils: Axel Giménez; inks: Axel Giménez; colors: Brad Anderson; letters: Rob Leigh | Doomslayer; Doomsday [Eradicator]; Doomsday (clones); Cyborg Superman [Hank Henshaw]; S.T.A.R. Labs |
| 9 | - | cover reprint (on interior page) | 1 | pencils: Kenneth Rocafort; inks: Kenneth Rocafort; colors: Kenneth Rocafort | Doomslayer |
| 10 | Reign of the Doomsdays, Part Four | comic story | 20 | script: Paul Cornell; pencils: Axel Giménez, Ronan Cliquet; inks: Axel Giménez, Ronan Cliquet; colors: Brad Anderson; letters: Rob Leigh | Phantom Zone Creature [Probe Creature]; Doomslayer; Doomsday [Eradicator] |
| 11 | Life Support | comic story | 10 | script: Damon Lindelof; pencils: Ryan Sook; inks: Ryan Sook; colors: Ryan Sook; letters: John J. Hill | brilliant scientist |
| 12 | Autobiography | comic story | 3 | script: Paul Dini; pencils: RB Silva; inks: Rob Lean; colors: Java Tartaglia; letters: John J. Hill | Sarva; I'iawa (flashback) |
| 13 | Friday Night in the 21st Century | comic story | 4 | script: Geoff Johns; pencils: Gary Frank; inks: Gary Frank; colors: Brad Anderson; letters: John J. Hill | Legion of Super-Heroes [Dawnstar; Wildfire; Blok; Ultra Boy; Lightning Lad; Shadow Lass; Cosmic Boy; Phantom Girl; Brainiac 5; Polar Boy; Night Girl; Saturn Girl; Colossal Boy; Lightning Lass; Timber Wolf] |
| 14 | The Incident | comic story | 9 | script: David S. Goyer; pencils: Miguel Sepulveda; inks: Miguel Sepulveda; colors: Paul Mounts; letters: Rob Leigh | Gabriel Wright; Royal Flush Gang (cameo) |
| 15 | Only Human | comic story | 15 | script: Richard Donner, Derek Hoffman; pencils: Matt Camp; inks: Matt Camp | Cliff Carter |
| 16 | The Evolution of the Man of Tomorrow | illustration | 2 | pencils: Brian Stelfreeze; inks: Brian Stelfreeze; colors: Brian Stelfreeze | |
| 17 | Action Comics #900 Variant | cover reprint (on interior page) | 1 | pencils: Alex Ross; inks: Alex Ross; colors: Alex Ross | |
| 18 | Action Comics #900 Variant | cover reprint (on interior page) | 1 | pencils: Adam Hughes; inks: Adam Hughes; colors: Adam Hughes | |
| 19 | Action Comics #901 Variant | cover reprint (on interior page) | 1 | pencils: Dan Jurgens; inks: Norm Rapmund; colors: Andrew Dalhouse | Doomsday [clones] |
| 20 | Action Comics #902 Variant | cover reprint (on interior page) | 1 | pencils: Jon Bogdanove; inks: Jon Bogdanove; colors: Paul Mounts | Doomsday (clone) |
| 21 | Action Comics #903 Variant | cover reprint (on interior page) | 1 | pencils: Denys Cowan; inks: Don Hudson; colors: Paul Mounts | Doomsday (clone) |
| 22 | Action Comics #904 Variant | cover reprint (on interior page) | 1 | pencils: Jerry Ordway; inks: Jerry Ordway; colors: Paul Mounts | Doomslayer |
| 23 | Doomsday Designs | illustration | 3 | pencils: Joe Prado | |