| 0 | - | cover | 1 | pencils: Carlos Pacheco; inks: Jesús Merino | Brainiac, Clark Kent, Superman |
| 1 | Superman vs. Brainiac | illustration | 1 | pencils: George Pérez, Kerry Gammill; inks: Brett Breeding; colors: Glenn Whitmore | Superman; Brainiac |
| 2 | Contents | table of contents | 1 | letters: typeset | |
| 3 | The Super-Duel in Space | comic story | 13 | script: Otto Binder; pencils: Al Plastino; inks: Al Plastino; editing: Jack Schiff, Mort Weisinger, George Kashdan | Superman (brief origin); Lois Lane; Brainiac (villain, intro); Professor Kimda; Superboy (flashback); Jonathan Kent (flashback); Martha Kent (flashback); Superboy (flashback) |
| 4 | Lana Lang, Superwoman! | comic story | 9 | script: Jerry Siegel; pencils: Curt Swan; inks: Stan Kaye; editing: Mort Weisinger | Lois Lane [as Super-Lois]; Lana Lang [as Super-Lana]; Superman [also appears as Clark Kent]; Brainiac; Perry White; Jimmy Olsen |
| 5 | The Team of Luthor and Brainiac! Part 1: The Deadly Duo! | comic story | 9 | script: Edmond Hamilton; pencils: Curt Swan; inks: George Klein; editing: Mort Weisinger | Lex Luthor (villain); Brainiac (origin, flashback, villain); Brainiac II (ancestor of Brainiac 5, introduction, origin, flashback); Superman (flashback); Var-Don |
| 6 | Part II: The Downfall of Superman! | comic story | 9 | script: Edmond Hamilton; pencils: Curt Swan; inks: George Klein; editing: Mort Weisinger | Lex Luthor (villain); Brainiac (villain); Jax-Ur; Professor Vakox; Phantom Zone inmates; Tharla; Lexorians (guest stars); Superman [Kal-El]; Lexor |
| 7 | Part III: The Hour of Kandor's Vengeance! | comic story | 8.67 | script: Edmond Hamilton; pencils: Curt Swan; inks: George Klein; editing: Mort Weisinger | Lex Luthor (villain); Brainiac (villain); Superman [Kal-El]; Superman Emergency Squad; Lexor; Tharla |
| 8 | Krypton Dies Again! | comic story | 15 | script: Cary Bates; pencils: Curt Swan; inks: Frank Chiaramonte; colors: Gene D'Angelo; letters: Ben Oda; editing: Julius Schwartz | Superman; Lois Lane; Perry White; Jimmy Olsen; Morgan Edge; Lana Lang; Steve Lombard; Oscar Asherman; Justice League of America [Batman; Wonder Woman; Green Lantern; Hawkman]; Supergirl; Drygur Moliom; Brainiac |
| 9 | No Tomorrow for Superman! | comic story | 17 | script: Cary Bates; pencils: Curt Swan; inks: Frank Chiaramonte; colors: Gene D'Angelo; letters: Milt Snapinn; editing: Julius Schwartz | Superman [Clark Kent]; Jimmy Olsen; Lana Lang; Josh Coyle; Brainiac; Hawkman |
| 10 | A Matter of Light and Death! | comic story | 17 | script: Cary Bates; pencils: Curt Swan; inks: Frank Chiaramonte; colors: Gene D'Angelo; letters: Karisha; editing: Julius Schwartz | Superman [Clark Kent]; Brainiac; Hawkman; Theodore J. Henkin; Jerry |
| 11 | Rebirth! | comic story | 23 | script: Marv Wolfman; pencils: Gil Kane; inks: Gil Kane; colors: Gene D'Angelo; letters: Ben Oda; editing: Julius Schwartz | Superman; Lois Lane; Lana Lang; Brainiac; The Omega Men [Kalista; Primus; Broot; Nimbus; Harpis] (cameo); Lord Satanis (flashback) |
| 12 | ...The Amazing Brainiac | comic story | 22 | script: John Byrne; pencils: Jerry Ordway; inks: John Beatty; colors: Anthony Tollin; letters: Albert DeGuzman; editing: Mike Carlin | Superman [Clark Kent; Kal-El]; Cat Grant; Jimmy Olsen; Adam Morgan; Jerry White; Lois Lane; Mr. Chin; Mrs. Chin; Ronnie Chin; Janet Jones; Selena the Beautiful Buxum Bearded Lady; Harry; Dr. Howard (first appearance); VILLAIN: Brainiac [Milton Fine; Vril Dox] (first post-Crisis appearance) |
| 13 | Man and Machine | comic story | 22 | script: Roger Stern; pencils: George Pérez, Kerry Gammill; inks: Brett Breeding; colors: Glenn Whitmore; letters: Bill Oakley; editing: Mike Carlin, Jon Peterson | Superman [Clark Kent; Kal-El]; Guardian [Jim Harper] (flashback); Dubbilex (flashback); Collin Thornton; Mara Talbot (first appearance); Dr. Augustine; VILLAINS: Brainiac [Vril Dox] (origin); Milton Fine (flashback); Sydney Happersen; Lex Luthor; Metallo [John Corben] (flashback) |
| 14 | Brainiac 13 | character profile | 1 | script: Scott Beatty; pencils: Ed McGuinness, Steve Kim; inks: Steve Kim; colors: Tommy Yune; editing: Maureen McTigue, Tony Bedard | Brainiac 13 |
| 15 | Sacrifice for Tomorrow | comic story | 23 | script: Joe Kelly; pencils: Germán García, Kano; inks: Marlo Alquiza; colors: Glenn Whitmore, Wildstorm FX; letters: Richard Starkings, Comicraft; editing: Eddie Berganza, Maureen McTigue | Superman [Clark Kent; Kal-El]; Lois Lane; Hourman [Matthew Tyler]; Red Tornado; Metal Men [Mercury; Platinum; Gold]; Lex Luthor; Lena Luthor; Brainiac 13 |
| 16 | Updated Action! | promo (ad from the publisher) | 1 | script: Marv Wolfman; pencils: Gil Kane; inks: Gil Kane | |