| 0 | - | cover | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: Jeff Lemire | |
| 1 | - | blank page(s) | 1 | | |
| 2 | Sweet Tooth, Book One | credits, title page | 1 | | |
| 3 | Sweet Tooth, Book One | credits, title page | 2 | | |
| 4 | Editorial Credits | credits, title page | 1 | letters: typeset | |
| 5 | Foreword | foreword, introduction, preface, afterword | 2 | script: Michael Sheen | |
| 6 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia | Gus [Sweet Tooth] |
| 7 | Out of the Deep Woods, Part One | comic story | 22 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | Gus [Sweet Tooth]; Gus' father (Death); Tom Jepperd |
| 8 | - | illustration | 1 | | |
| 9 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia | Sweet Tooth [Gus]; Tom Jepperd |
| 10 | Out of the Deep Woods, Part Two | comic story | 22 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | Sweet Tooth [Gus]; Tom Jepperd |
| 11 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia | Sweet Tooth [Gus] |
| 12 | Out of the Deep Woods 3 | comic story | 22 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | Sweet Tooth [Gus]; Tom Jepperd; Becky |
| 13 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia | Sweet Tooth [Gus]; Jepperd; Becky; Lucy |
| 14 | Out of the Deep Woods, Part 4 | comic story | 22 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | Sweet Tooth [Gus]; Jepperd; Lucy; Becky; Jacob; Susie (Death) |
| 15 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia | Sweet Tooth [Gus] |
| 16 | Out of the Deep Woods, Conclusion | comic story | 22 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | Sweet Tooth [Gus]; Mr. Jepperd |
| 17 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: José Villarrubia; colors: José Villarrubia | Tom Jepperd |
| 18 | In Captivity, Part 1 | comic story | 22 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | Tom Jepperd; Sweet Tooth [Gus]; Louise Jepperd (flashback); Bobby |
| 19 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia | Sweet Tooth [Gus] |
| 20 | In Captivity, Part 2 | comic story | 22 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | Louise Jepperd (flashback); Mrs. Powell (flashback); Tom Jepperd; Sweet Tooth [Gus]; Dr. Singh |
| 21 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia | Sweet Tooth [Gus]; Doctor Singh |
| 22 | In Captivity No. 3 | comic story | 22 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | Sweet Tooth [Gus]; Tommy Jepperd; Louise (flashback); Doctor Singh |
| 23 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia | Sweet Tooth [Gus] |
| 24 | In Captivity, Part 4 | comic story | 22 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | |
| 25 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia | Sweet Tooth [Gus] |
| 26 | - | illustration | 1 | | |
| 27 | In Captivity, Interlude: Back Woods | comic story | 22 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | |
| 28 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia | Sweet Tooth [Gus] |
| 29 | In Captivity, Conclusion | comic story | 23 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | Tom Jepperd; Johnny; Abbot; Louise Jepperd |
| 30 | - | cover reprint (on interior page) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia | Gus |
| 31 | - | illustration | 1 | | |
| 32 | The Singh Tapes | comic story | 21 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; colors: José Villarrubia; letters: Pat Brosseau | Gus [Sweet Tooth]; Dr. Singh; Jessup |
| 33 | Sweet Tooth Sketchbook | illustration | 9 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire; letters: Jeff Lemire | |
| 34 | Sweet Tooth: Ongoing Series Proposal | text story | 2 | script: Jeff Lemire; pencils: Jeff Lemire; inks: Jeff Lemire | |
| 35 | - | blank page(s) | 1 | | |
| 36 | The Boy and the Big Man | promo (ad from the publisher) | 1 | pencils: Jeff Lemire; inks: Jeff Lemire | |