| 0 | - | cover | 1 | pencils: Whilce Portacio; inks: Whilce Portacio | Colonel Jackson Dane |
| 1 | - | blank page(s) | 1 | | |
| 2 | Wetworks, Book One | credits, title page | 1 | pencils: Michael Golden; inks: Michael Golden | Red [Persephone]; Colonel Jackson Dane |
| 3 | Editorial Credits | credits, title page | 1 | pencils: Jason Pearson; inks: Jason Pearson | |
| 4 | Prelude 1 | cover reprint (on interior page) | 1 | pencils: Whilce Portacio; inks: Whilce Portacio | |
| 5 | - | comic story | 6 | script: Mike Carey; pencils: Whilce Portacio; inks: Trevor Scott; colors: Wendy Broome; letters: Jared Fletcher | |
| 6 | Prelude 2 | cover reprint (on interior page) | 1 | pencils: Whilce Portacio; inks: Whilce Portacio | |
| 7 | Once and Future | comic story | 8 | script: Whilce Portacio, John Arcudi; pencils: Whilce Portacio; inks: Richard Friend; colors: Studio F; letters: Comicraft | |
| 8 | Chapter 1 | cover reprint (on interior page) | 1 | pencils: Whilce Portacio; inks: Whilce Portacio | Colonel Jackson Dane |
| 9 | - | cover reprint (on interior page) | 1 | pencils: Ethan Van Sciver; inks: Ethan Van Sciver; colors: Carrie Strachan | |
| 10 | The Blood-Red Game, Part 1 of 3 | comic story | 22 | script: Mike Carey; pencils: Whilce Portacio; inks: Trevor Scott; colors: Wendy Broome; letters: Nick Napolitano | Wetworks; Colonel Jackson Dane; Red [Persephone]; Dustwalker [Ab-Death]; Mother One [Rachel L. Rhodes]; Bask; Spengler (death); Lasalle (death); Joel (death); Dr. Richard Stiles; Bethell; Buller |
| 11 | Chapter 2 | cover reprint (on interior page) | 1 | pencils: Whilce Portacio; inks: Whilce Portacio | Colonel Jackson Dane |
| 12 | The Blood-Red Game, Part 2 of 3 | comic story | 22 | script: Mike Carey; pencils: Whilce Portacio; inks: Richard Friend; colors: Wendy Broome; letters: Phil Balsman | Wetworks; Colonel Jackson Dane; Red [Persephone]; Dustwalker [Ab-Death]; Mother One [Rachel L. Rhodes]; Buller; Dr. Richard Stiles; Bethell; Vascar |
| 13 | Chapter 3 | cover reprint (on interior page) | 1 | pencils: Whilce Portacio; inks: Whilce Portacio | Wetworks; Colonel Jackson Dane; Red [Persephone]; Dustwalker [Ab-Death] |
| 14 | The Blood-Red Game, Part 3 of 3 | comic story | 22 | script: Mike Carey; pencils: Whilce Portacio; inks: Richard Friend; colors: Wendy Broome; letters: Jared Fletcher | Wetworks; Colonel Jackson Dane; Red [Persephone]; Dustwalker [Ab-Death]; Mother One [Rachel L. Rhodes]; Sebastian Ashe; O'Rourke (death); Vascar |
| 15 | Chapter 4 | cover reprint (on interior page) | 1 | pencils: Whilce Portacio; inks: Whilce Portacio | |
| 16 | I'll Break You First, Part 1 of 2 | comic story | 22 | script: Mike Carey; pencils: Whilce Portacio; inks: Richard Friend, Peter Guzman, Sandra Hope; colors: Wendy Broome; letters: Phil Balsman | |
| 17 | Chapter 5 | cover reprint (on interior page) | 1 | pencils: Whilce Portacio; inks: Whilce Portacio; colors: Whilce Portacio | |
| 18 | I'll Break You First, Part 2 of 2 | comic story | 22 | script: Mike Carey; pencils: Whilce Portacio; inks: Avalon Studios; colors: Wendy Broome; letters: Phil Balsman | |
| 19 | - | cover reprint (on interior page) | 1 | pencils: Eric Powell; inks: Eric Powell | |
| 20 | - | promo (ad from the publisher) | 1 | pencils: various; inks: various; letters: typeset | |
| 21 | - | blank page(s) | 1 | | |
| 22 | - | promo (ad from the publisher) | 1 | pencils: Whilce Portacio; colors: Wendy Broome | |