| 0 | Serpicool and McClod | cover | 1 | pencils: Mort Drucker; inks: Mort Drucker | Serpicool; Alfred E. Neuman; McClod |
| 1 | The Frog Prince | comic story | 1 | script: Jan van Wessum; pencils: Jack Rickard; inks: Jack Rickard | |
| 2 | - | table of contents | 1 | pencils: various; letters: typeset | |
| 3 | Letters Dept. | letters page | 2 | letters: typeset | |
| 4 | Serpicool | comic story | 8 | script: Stan Hart; pencils: Mort Drucker; inks: Mort Drucker | Al Pacino [as Serpicool]; Sal Carollo [as Mr. Serpicool]; Mildred Clinton [as Mrs. Serpicool]; Marlon Brando [as Don Vito Corleone]; Talia Shire [as Connie Corleone]; James Caan [as Sonny Corleone]; John Cazale [as Fredo Corleone]; Robert Duvall [as Tom Hagen]; Richard Castellano [as Peter Clemenza] |
| 5 | Trademark Graffiti | comic story | 4 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 6 | Alfred’s Poor Almanac | comic story | 1 | letters: typeset | Alfred E. Neuman |
| 7 | A Mad History of Sex | comic story | 6 | script: Larry Siegel; pencils: George Woodbridge; inks: George Woodbridge | |
| 8 | Don Martin Dept. Part 1: One Day in the City | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 9 | The Lighter Side of... the High Cost of Living | comic story | 5 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 10 | A Mad Guide to Status Symbols | comic story | 3 | script: Tom Koch; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 11 | Don Martin Dept. Part 2: One Day at Notre Dame | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 12 | A Mad Look at Funerals | comic story | 3 | script: Stan Hart; pencils: Bob Clarke; inks: Bob Clarke | |
| 13 | Follow-Up Letters to Advertisers | text article | 2 | script: Dick DeBartolo | |
| 14 | Talking Stamps | comic story | 1 | script: Frank Jacobs; pencils: Dumont Stamp Co., N.Y.C.; inks: Dumont Stamp Co., N.Y.C. | Patrick Henry; Thomas Jefferson; Susan B. Anthony; Betsy Ross; Christopher Columbus; Neil Armstrong; Thomas A. Edison; Pope Paul VI |
| 15 | The Mad Tennis Primer | comic story | 3 | script: Larry Siegel; pencils: Jack Davis; inks: Jack Davis | |
| 16 | Don Martin Dept. Part 3: One Day in the Patent Office | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin; letters: Don Martin | |
| 17 | McClod | comic story | 6 | script: Lou Silverstone; pencils: Angelo Torres; inks: Angelo Torres | Dennis Weaver [as Marshal Simp McClod]; J.D. Cannon [as Chief Cliffhead]; Diana Muldaur [as Crass]; Commissioner |
| 18 | What New Development Has Greatly Improved Highway Safety? | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 19 | Save the Eagle! | illustration | 1 | pencils: Bob Clarke; inks: Bob Clarke | |