| 0 | - | cover | 1 | pencils: Jack Rickard; inks: Jack Rickard; colors: Jack Rickard | |
| 1 | A Frozen Pupsicle | illustration | 0.125 | pencils: Don Martin; inks: Don Martin | |
| 2 | Merry Christmas, Y'all! | illustration | 0.125 | pencils: Paul Coker Jr.; inks: Paul Coker Jr.; letters: Paul Coker Jr. | Jimmy Carter |
| 3 | The Shootiest | comic story | 6 | script: Dick DeBartolo; pencils: Mort Drucker; inks: Mort Drucker | John Wayne [as J.B. Dukes]; Jimmy Stewart [as Dr. Horsefeathers]; Lauren Bacall [as Bland]; Ron Howard [as Killem]; Richard Boone [as Sweeney]; Hugh O'Brien [as Pulford]; Harry Morgan [as The Sheriff]; Richard Lenz [as Bodkins]; Henry Winkler [as Fonzie] (cameo) |
| 4 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 5 | If Fictional Characters Lived in the "Real World" of Today | cartoon | 3 | script: Arnoldo Franchioni; pencils: Arnoldo Franchioni; inks: Arnoldo Franchioni | |
| 6 | One Tuesday Morning on Main Street | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 7 | Mad "Death" Announcements | text story | 2 | script: Frank Jacobs | |
| 8 | The Lighter Side of Goofs | comic story | 5 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 9 | If Other Businesses Offered "No-Frills" Service | comic story | 3 | script: Stan Hart; pencils: George Woodbridge; inks: George Woodbridge | |
| 10 | Still More What's the Story...? | comic story | 2 | script: Don Edwing; pencils: Bob Clarke; inks: Bob Clarke | |
| 11 | Testimonial Roasts for Ordinary People | comic story | 4 | script: Arnie Kogen; pencils: Bob Jones; inks: Bob Jones | Frank Sinatra; Little Annie Fanny; Mickey Mouse; Donald Duck; Goofy; Henny Youngman; Foster Brooks; Steve Allen; Don Rickles; David Steinberg; Jan Murray; Albert Alligator; Pogo Possum; Alan King; Howard Cosell; Dean Martin; Burt Reynolds; Johnny Carson; Jack Carter; Pat Paulsen; Phyllis Diller; Tot |
| 12 | When You're Poor...and...When You're Rich | comic story | 2 | script: Frank Jacobs; pencils: Jack Davis; inks: Jack Davis | |
| 13 | One Wednesday Morning on a Desert Island | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 14 | Presenting the Original Mad Cover, and One Mad Moment Later | illustration | 3 | script: Don Edwing; pencils: Jack Rickard; inks: Jack Rickard | |
| 15 | Top Secret Minutes of Top Secret Meetings | comic story | 4 | script: Tom Koch; pencils: Harry North; inks: Harry North | |
| 16 | Footnotes* to Literature | comic story | 2 | script: Paul Peter Porges; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 17 | A Super Opportunity | comic story | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | Superman [Clark Kent] |
| 18 | One Dame at a Time | comic story | 5 | script: Larry Siegel; pencils: Angelo Torres; inks: Angelo Torres | Bonnie Franklin [as Mom]; MacKenzie Phillips [as Ghoulie]; Valerie Bertinelli [as Bobka]; Pat Harrington [as Drain Sniper] |
| 19 | One Morning Back on Main Street | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 20 | The Frog Prince III | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin; colors: Don Martin | |
| 21 | Mad Salutes the Automobile Industry | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee; colors: Al Jaffee | |