| 0 | Mad Invaders | cover | 1 | pencils: Bob Clarke; inks: Bob Clarke; colors: Bob Clarke | Alfred E. Neuman |
| 1 | Table of Contents | table of contents | 1 | pencils: various; inks: various; letters: typeset | |
| 2 | Letters Dept. | letters page | 1 | letters: typeset | |
| 3 | Video Games Based on Real Life | comic story | 5 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 4 | Don Martin Dept. Part I: One Fine Afternoon While Skydiving | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin; letters: Don Martin | |
| 5 | Questions We'd Like to Ask Some TV Advertisers | comic story | 4 | script: Tom Koch, Billy Doherty; pencils: Angelo Torres; inks: Angelo Torres | |
| 6 | The Mad "Cost of Living" Index | comic story | 2 | script: John Ficarra; pencils: Paul Coker; inks: Paul Coker | |
| 7 | The Lighter Side of... | comic story | 5 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 8 | Don Martin Dept. Part II: One Fine Afternoon at the Dentist | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 9 | Only a True Rock Fan Would... | comic story | 3 | script: Chris Hart; pencils: Jack Davis; inks: Jack Davis | |
| 10 | The Model Majority Manual | comic story | 7 | script: Stan Hart; pencils: George Woodbridge; inks: George Woodbridge | |
| 11 | A Mad Portfolio of... Quotes You Can Bet Were Never Said | photo story | 2 | script: Dick DeBartolo | Richard Nixon; Ed McMahon; Gene Simmons; Meatloaf; Charles Schulz; John McEnroe; Milton Berle; Nancy Reagan; Sammy Davis, Jr.; Marie Osmond; Jack Ritter |
| 12 | Spy vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | Black Spy; White Spy |
| 13 | The "Star Wars" Log: The Master Plan for Future Space Films | comic story | 5 | script: Frank Jacobs; pencils: Harry North; inks: Harry North | Obi-Wan Kenobi; Darth Vader; Chewbacca; Princess Leia; Han Solo; C-3PO; R2-D2; Luke Skywalker; Boba Fett; Yoda; Lando Calrissian |
| 14 | It's a Small Victory! | comic story | 2 | script: Dennis Snee; pencils: Jack Rickard; inks: Jack Rickard | |
| 15 | DeGenerate Hospital | comic story | 6 | script: Lou Silverstone; pencils: Mort Drucker; inks: Mort Drucker | Anthony Geary [as Puke Dispenser]; Genie Francis [as Rawer Whipper]; Denise Alexander [as Dr. Whipper]; Elizabeth Taylor [as Swellina Assinine]; Jacklyn Zeman [as Boobie Dispenser]; Doug Sheehan [as Shmoe Killy]; John Beradino [as Dr. Hardyhar]; Robert Young [as Dr. Mucus Wellby]; Emily McLaughlin [ |
| 16 | Don Martin Dept. Part III: One Not So Fine Afternoon Downtown | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 17 | Why Is a Taxpayer Like a Bottle of Wine? | activity | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee; colors: Al Jaffee | |
| 18 | The Urologist | comic story | 1 | script: John Caldwell; pencils: John Caldwell; inks: John Caldwell; colors: John Caldwell | |
| 19 | Drawn-Out Dramas | comic story | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés; letters: Sergio Aragonés | |