| 0 | - | cover | 1 | pencils: Jack Rickard; inks: Jack Rickard; colors: Jack Rickard | Alfred E. Neuman |
| 1 | Why Kill Yourself? | promo (ad from the publisher) | 1 | pencils: Jack Davis; inks: Jack Davis; colors: Jack Davis | |
| 2 | - | table of contents | 1 | pencils: various; inks: various; letters: typeset | |
| 3 | - | letters page | 1 | letters: typeset | |
| 4 | Collect Double Indemnity! | promo (ad from the publisher) | 1 | pencils: various; inks: various; letters: typeset | |
| 5 | The Greatest American Zero | comic story | 7 | script: Lou Silverstone; pencils: Mort Drucker; inks: Mort Drucker | Batman, Robin, Spider-Man, Superman |
| 6 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 7 | One Gloomy Day in the Dungeons | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 8 | The Mad Student's Hate Book | comic story | 4 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 9 | If Junk Mail Had Always Existed | comic story | 3 | script: Tom Koch; pencils: George Woodbridge; inks: George Woodbridge | |
| 10 | A Mad Guide to First Aid | comic story | 5 | script: Dick DeBartolo; pencils: Angelo Torres; inks: Angelo Torres | |
| 11 | The Lighter Side of... | comic story | 5 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 12 | One Sunny Day in the Dungeons | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 13 | Mad's ABC's of Writing Successful Exams and Term Papers | comic story | 4 | script: Tom Koch; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 14 | Look Slim and Trim Without Diet or Strenuous Exercise | comic story | 2 | script: Paul Peter Porges; pencils: Paul Peter Porges; inks: Paul Peter Porges | |
| 15 | Spy Vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy, The White Spy |
| 16 | Mad's Occult Promoter of the Year | comic story | 4 | script: Frank Jacobs; pencils: Jack Davis; inks: Jack Davis | Howard Gosell; Cosmo Mantra |
| 17 | Mad's Modern Disclaimers to the Ten Commandments | comic story | 3 | script: John Ficarra; pencils: Bob Clarke; inks: Bob Clarke | |
| 18 | One Happy Day in the Dungeons | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 19 | Mad Looks in on Public Television | comic story | 4 | script: Larry Siegel; pencils: Harry North; inks: Harry North | Alistair Cooke; Jacques Cousteau; Orson Welles; Big Bird |
| 20 | Why Are New "Reaganomics" Like Old Reagan Movies? | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee; colors: Al Jaffee | |
| 21 | The Pied Piper | comic story | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés; colors: Sergio Aragonés | |