| 0 | Featuring the Mad Computer Program | cover | 1 | pencils: Al Jaffee; inks: Al Jaffee | Alfred E. Neuman |
| 1 | You'll Flip Over These Flubs! | promo (ad from the publisher) | 1 | | Alfred E. Neuman |
| 2 | - | table of contents | 1 | pencils: various; letters: typeset | |
| 3 | Random Samplings of Readers Mail | letters page | 2 | letters: typeset | |
| 4 | Mad's Academy Awards for Teenage Films | comic story | 5 | script: Arnie Kogen; pencils: Mort Drucker; inks: Mort Drucker | Dick Martin; Tom Hulcer; Gene Siskel; Roger Ebert; Jacqueline Briskette; Ally Cheaty; Sean Punk; Ray Walston; Chevy Chase; Neil Izzy; Pat Propp; Gregory Peck; Scott Bayou |
| 5 | Spy vs. Spy | comic story | 1 | script: Anthony Prohías; pencils: Anthony Prohías; inks: Anthony Prohías | |
| 6 | The Lighter Side of... | comic story | 5 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 7 | A Fairy Tale We'd Like to See | comic story | 1 | script: John Rios; pencils: Bob Jones; inks: Bob Jones | Prince |
| 8 | A Mad Look at Some Not-So-Famous First Attempts | comic story | 2 | script: Mike Snider; pencils: Al Jaffee; inks: Al Jaffee | Jim McKay |
| 9 | Goons, They Know How It's Done | comic story | 2 | script: Frank Jacobs; pencils: Mort Drucker; inks: Mort Drucker | Hulk Hogan; Captain Lou; Big John Studd; Sarge Slaughter; "Rowdy" Roddy; Patera; Andre the Giant |
| 10 | The Mad Computer Primer | comic story | 2 | script: John Boni; pencils: Al Jaffee; inks: Al Jaffee | |
| 11 | Practical Computer Programs for Normal Everyday Use | comic story | 2 | script: Dick DeBartolo; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 12 | One Morning at the Office | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 13 | The Computer Company President of the Year | comic story | 4 | script: Dick DeBartolo; pencils: Harry North; inks: Harry North | Rivaldo Jivera |
| 14 | Casey at the Byte | comic story | 3 | script: Frank Jacobs; pencils: Don Martin; inks: Don Martin | |
| 15 | If Computers Are So Brilliant... | comic story | 2 | script: Tom Koch; pencils: George Woodbridge; inks: George Woodbridge | |
| 16 | Mad's Guide to Computer Language | comic story | 2 | script: Charlie Kadau; pencils: Jack Davis; inks: Jack Davis | |
| 17 | The Mad Computer Program | text article | 4 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 18 | Mad's Celebrity Supermarket | comic story | 3 | script: Joe Raiola, Charlie Kadau; pencils: Bob Clarke; inks: Bob Clarke | Charles Bronson; Billy Graham; John Candy; Burt Reynolds; Mark Hamill; Bette Midler; Arnold Schwarzenegger; Bryant Gumbel; Eddie Murphy; E.T.; Indiana Jones; Al Pacino; Stevie Wonder |
| 19 | Goofies | comic story | 5 | script: Stan Hart; pencils: Jack Davis; inks: Jack Davis | Mucus; Datum |
| 20 | Justice Once | comic story | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 21 | Which Gruesome Twosome is Responsible for the Premature Passing of the Dearly Departed? | activity | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 22 | The Weinburger | illustration | 1 | script: Al Jaffee; pencils: Will Elder; inks: Harvey Kurtzman | Ronald Reagan |