| 0 | Spend The Holidays With...Lindsay! Nicole! Britney! Paris! | cover | 1 | pencils: Richard Williams; inks: Richard Williams; colors: Richard Williams | Lindsay Lohan; Nicole Richie; Britney Spears; Paris Hilton; Alfred E. Neuman |
| 2 | Departments | table of contents | 1 | script: Dick DeBartolo | Alfred E. Neuman; Donald Rumsfeld |
| 3 | Random Samplings of Reader Mail | letters page | 2.53 | script: John Ficarra, Scott Gosar; pencils: Scott Gosar, Steve Greenberg, Bill Bramhall; inks: Scott Gosar, Steve Greenberg, Bill Bramhall; colors: Scott Gosar | Alfred E. Neuman; Bill English; Sam Huntington; Nick Kroll; Jeff Daniel Phillips; Black Spy; White Spy; Bill Gaines; Mark Holsman; Mahmoud Ahmadinejad; Hillary Clinton |
| 4 | Statement of Ownership | statement of ownership | 0.14 | script: Paul Levitz | |
| 5 | - | credits, title page | 0.33 | letters: typeset | |
| 8 | The Fundalini Pages | comic story | 3 | script: various; pencils: various; inks: various; letters: typeset | Britney Spears; Fred Thompson; Leona Helmsley; Larry Craig; David Chase; Joe Bitterman |
| 9 | Bring Our Troops Home From Iran! | illustration | 1 | pencils: Mark Fredrickson; inks: Mark Fredrickson | Alfred E. Neuman |
| 10 | MAD Deconstructs TV Talk Shows | comic story | 3 | script: Desmond Devlin; pencils: Sam Viviano; inks: Sam Viviano | Stephen Colbert; Jon Stewart; Jimmy Neutron (cameo); Marco Crandall |
| 13 | Juggles | comic story | 1 | script: Mo Willems; pencils: Tom Bunk; inks: Tom Bunk | |
| 15 | You're Not Exactly Full of The True Spirit of Christmas If... | comic story | 2 | script: John Caldwell; pencils: John Caldwell; inks: John Caldwell; letters: John Caldwell | |
| 17 | Are We Winning The War On Terrorism? | comic story | 2 | script: Barry Liebmann; pencils: Ward Sutton; inks: Ward Sutton | Geraldo Rivera; Rudy Giuliani; Donald Rumsfeld; Dick Cheney; Condoleezza Rice; Osama bin Laden; George Bush |
| 18 | The Don Martin 2008 Calendar | illustration | 2 | pencils: Don Martin; inks: Don Martin | |
| 19 | NEW Blose QuiteDiscomforting 3 Acoustic Noise-Cancelling Headphones | comic story | 1 | script: John Ficarra; pencils: Irving Schild; inks: Irving Schild; colors: Irving Schild | |
| 21 | Millions of Trees Gave Their Lives For These Books | promo (ad from the publisher) | 1 | pencils: ? (photo); inks: ? (photo); colors: ? (photo); letters: typeset | |
| 22 | Ways To Keep Voters Interested Until Election Day | comic story | 2 | script: Teresa Burns Parkhurst; pencils: Teresa Burns Parkhurst; inks: Teresa Burns Parkhurst; letters: Teresa Burns Parkhurst | Hillary Clinton; Kirsti Alley; Rudy Giulani; Barack Obama; Chris Dodd; Katie Couric |
| 23 | The MAD World of Family Life | comic story | 3 | script: Stan Sinberg; pencils: Marc Hempel; inks: Marc Hempel | |
| 24 | Monroe and...The Tutor | comic story | 4 | script: Anthony Barbieri; pencils: Tom Fowler; inks: Tom Fowler; colors: Carl Peterson | Monroe; Mr. Bines; Inga; Dylan; Monroe's mother; Monroe's father; Monroe's grandfather; Charles Stingler; childlover4000; No English; Walter |
| 25 | You'll Go Head Over Heels For This Issue! | promo (ad from the publisher) | 0.5 | pencils: ? (photo); inks: ? (photo); colors: ? (photo); letters: typeset | Tony Hawk |
| 27 | Spy Vs. Spy | comic story | 2 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper | Black Spy; White Spy |
| 28 | What The Heck Is The Difference? | activity | 1 | pencils: Norman Mingo; inks: Norman Mingo; colors: Norman Mingo | Alfred E. Neuman |
| 29 | A MAD Look At Sports Scandals | comic story | 4 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 30 | Not So Hot Topic Catalog | comic story | 5 | script: Scott Maiko, Albert Crudo; pencils: Irving Schild; inks: Irving Schild; colors: Irving Schild | |
| 32 | What Primitive Form of Sub-Human Life Has Recently Been Discovered? | activity | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | Michael Vick |
| 33 | Drawn-Out Dramas | comic story | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |