| 0 | Our Slickest Issue Yet! | cover | 1 | pencils: Mark Fredrickson; inks: Mark Fredrickson; colors: Mark Fredrickson | Alfred E. Neuman |
| 2 | Departments | table of contents | 1 | pencils: various; inks: various; letters: typeset | Alfred E. Neuman; Dora The Explorer; Sarah Palin; Jesus Christ; George Washington |
| 3 | Random Samplings of Reader Mail | letters page | 3.25 | script: John Ficarra; pencils: Dave Berg; inks: Dave Berg; colors: Dave Berg | Jason Salas; Michelle Dwyer; Bob Machuga; Jason Katzenstein; Conan O'Brien; Alfred E. Neuman; Julianna Harwood |
| 4 | Subscribe To MAD! | promo (ad from the publisher) | 1 | pencils: Mark Fredrickson; inks: Mark Fredrickson; colors: Mark Fredrickson | Alfred E. Neuman |
| 5 | An Offer You Can't De-Fuse! | promo (ad from the publisher) | 0.5 | colors: Vick Arkoff, BG183, Tats Cru | Black Spy; White Spy |
| 6 | - | credits, title page | 0.25 | letters: typeset | |
| 7 | Subscribe To MAD And Own A Piece of MAD History! | promo (ad from the publisher) | 1 | pencils: Norman Mingo; inks: Norman Mingo | Alfred E. Neuman |
| 8 | The Fundalini Pages | comic story | 5 | script: Jeff Kruse, P. C. Vey, Emily Flake, John Caldwell, Desmond Devlin, Arie Kaplan; pencils: Sam Viviano, Paul Coker, P. C. Vey, Sam Sisco, Gary Hallgren, John Caldwell; inks: Sam Viviano, Paul Coker, P. C. Vey, Sam Sisco, Gary Hallgren, John Caldwell | Charlie Sheen; Betty White; Elena Kagan; Justin Bieber; Lucky Eddie; Helga; Lady Gaga [the Horrible]; Melvin; Jenkins |
| 9 | Glee Blows | illustration | 1 | pencils: ? (photo); inks: ? (photo); colors: ? (photo); letters: typeset | |
| 10 | Tea-Bagger Proof That Obama Is A Terrorist / Socialist | comic story | 2 | script: Stan Sinberg; pencils: Hermann Mejía; inks: Hermann Mejía | |
| 12 | A MAD Look At Racial Profiling | comic story | 4 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés; colors: Tom Luth | |
| 13 | Worst-Selling Children's Books | comic story | 2 | script: Jeff Kruse; pencils: Scott Bricher, Redbaron / Dreamstime.com, Julien Tromeur / Dreamstime.com; inks: Scott Bricher, Redbaron / Dreamstime.com, Julien Tromeur / Dreamstime.com | R. L. Stine; Sally Smartass; Dora The Explorer; Tommy Turtle; Mr. Caldecott; Stupid Bear; Darnell; Ishmael Terwilliger |
| 14 | Spy Vs. Spy | comic story | 2 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper | Black Spy; White Spy |
| 15 | Inspirational Wall Plaques That Never Caught On | text story | 2 | script: Jeff Kruse | |
| 16 | Planet Tad!!!!! | text story | 2 | script: Tim Carvell; pencils: Brian Durniak; inks: Brian Durniak | |
| 17 | 9 Ways To Pass The Time In Your Doctor's Waiting Room | comic story | 2 | script: Teresa Burns Parkhurst; pencils: Teresa Burns Parkhurst; inks: Teresa Burns Parkhurst; letters: Teresa Burns Parkhurst | |
| 18 | MAD's Oh-So Negative True Blood Outtakes | comic story | 2 | pencils: ? (photo); inks: ? (photo); colors: ? (photo); letters: typeset | |
| 19 | Gulf Of Mexico Oil Spill Response | text story | 1 | script: Dick DeBartolo | |
| 20 | The Strip Club | comic story | 4 | script: Joey Alison Sayers, Dustin Glick, Todd Clark, Kit Lively, Douglas Paszkiewicz, Vic Black; pencils: Joey Alison Sayers, Dustin Glick, Todd Clark, Scott Nickel, Douglas Paszkiewicz, Vic Black; inks: Joey Alison Sayers, Dustin Glick, Todd Clark, Scott Nickel, Douglas Paszkiewicz, Vic Black; letters: Joey Alison Sayers, Dustin Glick, Todd Clark, Scott Nickel, Douglas Paszkiewicz, Vic Black | The Tooth Fairy |
| 21 | If Jesus Walked Among Us: The Gulf Coast | illustration | 1 | pencils: Richard Williams; inks: Richard Williams; colors: Richard Williams | Jesus Christ |
| 22 | TMZZZ | comic story | 2 | script: Jacob Lambert; pencils: Xandros / Dreamstime.com, Karimala / Dreamstime.com, Kuzma / Dreamstime.com; inks: Xandros / Dreamstime.com, Karimala / Dreamstime.com, Kuzma / Dreamstime.com; colors: Xandros / Dreamstime.com, Karimala / Dreamstime.com, Kuzma / Dreamstime.com | Snooki; Care Bear; Barbara Bush; Angela Lansbury; Carrot Top; Rihanna; Eric Roberts; Lindsay Lohan; Abraham Lincoln |
| 23 | Rejected Stamp Collections | comic story | 2 | script: Jeff Kruse; pencils: Bob Staake, Drew Friedman; inks: Bob Staake, Drew Friedman | George Washington; Abraham Lincoln; Richard Nixon; Theodore Roosevelt; Harry Reems; John Holmes; Ron Jeremy; Mike Horner; Adolf Hitler; Fidel Castro; Barack Obama; Sammy Sosa; Yasser Arafat; Cuba Gooding, Jr.; Milli Vanilli; Hillary Clinton |
| 24 | The Darker Side Of The Lighter Side | comic story | 3 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | Roger Kaputnik |
| 25 | The Wizard of O | comic story | 6 | script: Desmond Devlin; pencils: Tom Richmond; inks: Tom Richmond | Dorothy; Bo-Bo; Pundits [Karl Rove; Ann Coulter; Pat Buchannan; James Carvell; Newt Gingrinch; Michael Moore; Rush Limbaugh; John Stewart; Sean Hanitty; Stephen Colbert]; Unfair-Crow [Bill O'Reilly]; The Spin Man [Keith Olberman]; the lion [Glenn Beck]; Wizard of O [Barack Obama]; Witless Witch of T |
| 26 | The MAD Vault 2001 | comic story | 3 | script: Mike Snider, Tom Cheney, Desmond Devlin, Scott Maiko, John Caldwell, Duck Edwing; pencils: Rick Tulka, George Woodbridge, Tom Cheney, Mark Fredrickson, Tom Richmond, John Caldwell; inks: Rick Tulka, George Woodbridge, Tom Cheney, Mark Fredrickson, Tom Richmond, John Caldwell | Alfred E. Neuman; Malcontent; Harry Potter; Barbra Streisand; Hannibal Lechter; Eminem; Alan Greenspan; Tom Hanks |
| 27 | It Happened One Morning | comic story | 1 | script: Michael Gallagher; pencils: Tom Bunk; inks: Tom Bunk | |
| 28 | What Strospheric Condition Caused Many Not To Fly This Year? | activity | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 29 | Drawn Out Dramas | comic story | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |