| 0 | Alfred E. Neuman For President | cover | 1 | pencils: Kelly Freas; inks: Kelly Freas; colors: Kelly Freas | Hubert Humphrey, Lyndon Johnson First, John F. Kennedy, Alfred E. Neuman, Richard Nixon, Adlai Stevenson, Harry S. Truman |
| 1 | Weak Coffee Sales Gives Us Growers Java Jitters! | comic story | 1 | script: Al Jaffee; pencils: Kelly Freas; inks: Kelly Freas | |
| 2 | Departments | foreword, introduction, preface, afterword | 1 | pencils: various (see Notes); inks: various (see Notes); letters: typeset | |
| 3 | Start Your Own Hall Of Fame | promo (ad from the publisher) | 0.25 | pencils: Lester Krauss; inks: Lester Krauss | |
| 4 | Campaign For The MAD Vote | promo (ad from the publisher) | 0.5 | pencils: ? (photo); inks: ? (photo); letters: typeset | |
| 5 | Random Samplings of Reader Mail | letters page | 1 | script: Albert B. Feldstein, John Rogers | Tony Randall; Lyle Bettger |
| 6 | A Little Knowledge Is A Dangerous Thing | promo (ad from the publisher) | 0.2 | letters: typeset | |
| 7 | Put A Little Fun In Your Life! | promo (ad from the publisher) | 0.05 | pencils: Norman Mingo; inks: Norman Mingo | Alfred E. Neuman |
| 8 | Madison Avenue's Political Ad Campaigns | comic story | 6 | script: Gary Belkin; pencils: George Woodbridge; inks: George Woodbridge | Hubert Humphrey, Lyndon Johnson First, John F. Kennedy, Richard Nixon, Adlai Stevenson |
| 9 | MAD's Modern Olympic Games | text story | 3 | script: Tom Koch; pencils: Mort Drucker; inks: Mort Drucker | |
| 10 | The Chiropractor | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 11 | MAD Bubble Gum Cards | text story | 4 | script: Tom Koch; pencils: Joe Orlando; inks: Joe Orlando | Alfred E. Neuman |
| 12 | The Good Woman In Africa | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 13 | How Publicity Works | comic story | 3 | script: Frank Jacobs; pencils: Bob Clarke, Joe Orlando; inks: Bob Clarke, Joe Orlando | Senator Ardsley Stonehenge |
| 14 | The Garbage Explosion | comic story | 3 | script: Sy Reit; pencils: Bob Clarke; inks: Bob Clarke | |
| 15 | The MAD "Comic" Opera | comic story | 6 | script: Frank Jacobs; pencils: Wallace Wood; inks: Wallace Wood | Archie Andrews, Blondie Bumstead, Dagwood Bumstead, Steve Canyon, Cicero's Cat First, John Clayton, Denny Colt, Daisy Mae Scragg, Mr. Dithers, Dondi First, Eugene the Jeep, Flash Gordon, Andy Gump, Smilin' Jack |
| 16 | Scenes We'd Like To See: The Race Through The Jungle | comic story | 1 | pencils: Mort Drucker; inks: Mort Drucker | |
| 17 | Honest Ads | comic story | 4 | script: Tom Koch; pencils: Bob Clarke; inks: Bob Clarke | Sammy Getzoff |
| 18 | Patty Play Dolls | comic story | 3 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 19 | MAD's TV "Alfie" Awards | comic story | 3 | script: Sy Reit; pencils: Mort Drucker; inks: Mort Drucker | Bert Parks; Jack Paar; Jose Melis; Dean Martin; Gale Storm; John Daly; Bennett Cerf (cameo); Dorothy Kilgallen (cameo); Desi Arnaz; Lucille Ball (cameo); Steve Allen; Gardner McKay |
| 20 | The Tourist And The Italian Urchins | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 21 | The U.S. Army Chicken Officer's Field Manual | text article | 5 | script: Larry Siegel; pencils: Bob Clarke; inks: Bob Clarke | |
| 22 | The Chase | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 23 | More MAD "Y'OX" | text story | 0 | | Marginal Marvin |
| 24 | Announcing...A Twin Launching From The MAD Pad | promo (ad from the publisher) | 1 | pencils: Lester Krauss; inks: Lester Krauss | |
| 25 | Crocked | comic story | 1 | pencils: Kelly Freas; inks: Kelly Freas; colors: Kelly Freas | Frank Kelly Freas; Rummie Walker |