| 0 | It's Gonna Be a Mad Year | cover | 1 | pencils: Norman Mingo; inks: Norman Mingo; colors: Norman Mingo | Alfred E. Neuman |
| 1 | She Was Irresistible! | cartoon | 1 | pencils: Bob Clarke; inks: Bob Clarke; colors: Bob Clarke; letters: Bob Clarke | |
| 2 | Vital Features | table of contents | 1 | pencils: various; inks: various; letters: typeset | |
| 3 | The Most Controversial Book Ever! | promo (ad from the publisher) | 0.41 | pencils: ? (photo); inks: ? (photo); letters: typeset | |
| 4 | Now...in 3-D! | promo (ad from the publisher) | 0.17 | pencils: ? (photo); inks: ? (photo); letters: typeset | |
| 5 | Why Trade a Headache for an Upset Stomach? | promo (ad from the publisher) | 0.19 | pencils: ? (photo); inks: ? (photo); letters: typeset | |
| 6 | Letters Dept. | letters page | 0.65 | pencils: ? (photo); inks: ? (photo); letters: typeset | Gardner McKay (photograph) |
| 7 | - | statement of ownership | 0.23 | script: William M. Gaines | |
| 8 | Let Us Slip You a "Mickey" for Your Mantle | promo (ad from the publisher) | 0.35 | pencils: ? (photo); inks: ? (photo); letters: typeset | |
| 9 | The Man of Science | comic story | 4 | script: Larry Siegel; pencils: Mort Drucker; inks: Mort Drucker | Charlie Brown, Tony Curtis, Doris Day, Dennis the Menace, William Frawley First |
| 10 | Early One Morning | comic story | 2 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 11 | The Wall Street Jungle | text story | 4 | script: Phil Hahn; pencils: Joe Orlando; inks: Joe Orlando | |
| 12 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy, The White Spy |
| 13 | Admissions of Dishonesty Still Don't Make It Right | comic story | 3 | script: Arnie Kogen; pencils: Joe Orlando; inks: Joe Orlando | |
| 14 | Kitzel's Department Store | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 15 | Playkid | comic story | 7 | script: Larry Siegel; pencils: Bob Clarke; inks: Bob Clarke | |
| 16 | A Mad Peek Through the Microscope | comic story | 3 | script: Phil Hahn; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | Alfred E. Neuman |
| 17 | MAD's Comprehensive Small Irritation Insurance | comic story | 4 | script: Sy Reit; pencils: George Woodbridge; inks: George Woodbridge | Bert Parks (television still photo) |
| 18 | Guest Shots | comic story | 5 | script: Tom Koch; pencils: Mort Drucker, Wally Wood; inks: Mort Drucker, Wally Wood | Dagwood Bumstead, Bing Crosby, Dennis the Menace, Donald Duck, Bob Hope, Little Orphan Annie, Frank Sinatra, Superman, Dick Tracy, Li'l Abner Yokum, Alfred Hitchcock, Jerry Lewis, Dean Martin, Joe Palooka |
| 19 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy, The White Spy |
| 20 | Mad's "Do-It-Yourself" Auto Repair Manual | comic story | 3 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 21 | Mad's 1961 TV Preview | comic story | 2 | script: Gary Belkin; pencils: Bob Clarke; inks: Bob Clarke | Charlie Chaplin |
| 22 | Mad Salutes an Unsung Hero | comic story | 4 | script: Don Reilly; pencils: George Woodbridge; inks: George Woodbridge | Alfred E. Neuman |
| 23 | After the Rains | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 24 | Caramba! I'm No Herk! | promo (ad from the publisher) | 1 | pencils: Lester Krauss; inks: Lester Krauss | |
| 25 | What Sort of Man Reads Mad? | cartoon | 1 | pencils: Lester Krauss; inks: Lester Krauss; colors: Lester Krauss | |