| 0 | Happy New Year Issue | cover | 1 | pencils: Norman Mingo; inks: Norman Mingo; colors: Norman Mingo | Alfred E. Neuman |
| 1 | If Kids Designed Their Own Christmas Toys | comic story | 4 | script: Al Jaffee; pencils: Al Jaffee, Lester Krauss; inks: Al Jaffee, Lester Krauss | |
| 2 | Alfred's Poor Almanac | comic story | 1 | script: Frank Jacobs | |
| 3 | In the Doctor's Office | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 4 | If the U.S. Government Bought Like the U.S. Public Buys | comic story | 4 | script: Stan Hart; pencils: George Woodbridge; inks: George Woodbridge | |
| 5 | Speaking From Pictures | comic story | 2 | script: Gerald Gardner | John Kennedy; Barry Goldwater; Richard Nixon; Lyndon Johnson; Harry Truman; Caroline Kennedy; Robert Kennedy |
| 6 | TV Pilot Films That Never Made It | comic story | 4 | script: Stan Hart; pencils: Mort Drucker; inks: Mort Drucker | Dorothy Collins; Snooky Lanson; Hugh Hefner; Casey Stengel; Billie Sol Estes; Richard Burton; Burl Ives |
| 7 | A Mad Look at the U.S. Space Effort | comic story | 2 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 8 | Seeing Isn't Always Believing | comic story | 4 | script: Frank Jacobs; pencils: Wally Wood; inks: Wally Wood | |
| 9 | The Lighter Side of Winter | comic story | 4 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 10 | Modern Teenage Sports | comic story | 3 | script: Arnie Kogen; pencils: George Woodbridge; inks: George Woodbridge | |
| 11 | The Assassination | comic story | 1 | pencils: Joe Orlando; inks: Joe Orlando | |
| 12 | When Advertising Takes Over Magazines Completely | comic story | 2 | pencils: Bob Clarke; inks: Bob Clarke | |
| 13 | Mad's Modern Aids to Happier Living | comic story | 3 | script: Don Reilly; pencils: Joe Orlando; inks: Joe Orlando | |
| 14 | Mad's Movie Theater Owner of the Year | comic story | 4 | script: Larry Siegel; pencils: Jack Rickard; inks: Jack Rickard | Dorothy Kilgallen [as Dorothy Killfifth]; Irving Mulet |
| 15 | In a Sicilian Restaurant | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 16 | Mad's Merry Christmas Happy New Year Alphabet Book | comic story | 4 | script: Frank Jacobs; pencils: Bob Clarke; inks: Bob Clarke | |
| 17 | At the Barber Shop | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 18 | A Very Merry Christmas | cartoon | 1 | pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 19 | Guzzlemidt Rotgut | illustration | 1 | script: Al Jaffee; pencils: Bob Clarke, Lester Krauss; inks: Bob Clarke, Lester Krauss | |