| 0 | Mad Proudly Presents a New First Issue That Tells the World Where to Stick It! | cover | 1 | letters: typeset | |
| 1 | Insulting Hand Gestures | illustration | 2 | letters: typeset | |
| 2 | - | cover | 1 | pencils: Jason Edmistion; inks: Jason Edmistion | |
| 3 | - | table of contents | 2 | pencils: Harvey Kurtzman; inks: Harvey Kurtzman | |
| 4 | Star Bores: Half-Assed Jedi | comic story | 6 | script: Desmond Devlin; pencils: Tom Richmond; inks: Tom Richmond | |
| 5 | A Mad Look at Harassment | comic story | 4 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés; colors: Carrie Strachan; letters: Sergio Aragonés | |
| 6 | Is Your Tiki Leaky? | promo (ad from the publisher) | 1 | letters: typeset | |
| 7 | Make America Greet Again | comic story | 3 | script: Teresa Burns Parkhurst; pencils: Teresa Burns Parkhurst; inks: Teresa Burns Parkhurst | |
| 8 | Spy vs Spy | comic story | 2 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper; letters: Peter Kuper | |
| 9 | The Wisenheim Museum | illustration | 1 | script: Ron English; pencils: Ron English, Basil Wolverton; inks: Ron English, Basil Wolverton; colors: Ron English | |
| 10 | Potrzebie Comics | comic story | 1 | pencils: Kerry Callen; inks: Kerry Callen | |
| 11 | It's Bring Your Sidekick to Work Day! | comic story | 3 | script: Kerry Callen; pencils: Kerry Callen; inks: Kerry Callen | |
| 12 | The 27 Club | comic story | 5 | script: Luke McGarry; pencils: Luke McGarry; inks: Luke McGarry | |
| 13 | Boonies Burbs and Burgs | comic story | 4 | script: Bob Fingerman; pencils: Bob Fingerman; inks: Bob Fingerman | |
| 14 | Mad's Movie Mogul Guide Marketing Chick Flicks to The Dude Bro Demographic | photo story | 4 | script: Mary Trainor; pencils: Mary Trainor; inks: Mary Trainor | |
| 15 | Pop Culture That Didn't Make It Into... Ready Player One | comic story | 2 | script: Brian Posehn; pencils: Peter Bagge; inks: Peter Bagge | |
| 16 | Starchie Reconstituted | comic story | 9 | script: Ian Boothby; pencils: Tom Richmond; inks: Tom Richmond | |
| 17 | Movies We'd Like to See (on the Cutting Room Floor) | illustration | 1 | script: Mary Trainor; pencils: Mary Trainor; inks: Mary Trainor | |
| 18 | - | comic story | 4 | script: Paula Sevenbergen, Lars Kenseth, Peter Kuper, Kenny Keil, Jason Chatfield, Johnny Sampson; pencils: Alejandro Rivas, Lars Kenseth, Peter Kuper, Johnny Sampson, Jason Chatfield, Bob Eckstein; inks: Alejandro Rivas, Lars Kenseth, Peter Kuper, Johnny Sampson, Jason Chatfield, Bob Eckstein; colors: Doug Thompson | |
| 19 | - | letters page | 3 | script: Alex Taffer | |
| 20 | The Madifesto | text story | 1 | script: Casey Boyd | |
| 21 | - | comic story | 0.67 | script: Dan Telfer; pencils: Mike Holmes; inks: Mike Holmes | |
| 22 | - | credits, title page | 0.33 | letters: typeset | |
| 23 | What Is the Last Thing Many Americans Do Before Dying? | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee; colors: Al Jaffee | |
| 24 | Mad's Guide to Protecting Your Home | comic story | 1 | script: Dick DeBartolo; pencils: Timothy Shamey; inks: Timothy Shamey | |
| 25 | Thanks for Picking Mad! | illustration | 1 | letters: typeset | |