| 0 | What, Me Worry? | cover | 1 | pencils: Kelly Freas; inks: Kelly Freas; colors: Kelly Freas | Alfred E. Neuman |
| 1 | I Don't Want To Be A King | comic story | 1 | pencils: Kelly Freas; inks: Kelly Freas | Edward, Duke of Wales |
| 2 | Departments | table of contents | 1 | pencils: Harvey Kurtzman, Bill Elder; inks: Harvey Kurtzman, Bill Elder | Alfred E. Neuman |
| 3 | Gunsmoked | comic story | 4 | pencils: Jack Davis; inks: Jack Davis | Madd Dillinger; Gambler Dan; Blacksmith Sam; Chestnut; Doc; Kiddie; Mayor Melvin |
| 4 | A Collection of Daily Strips | comic story | 2 | pencils: Bill Elder; inks: Bill Elder | Brunette; Dogwood; Punjoke; Little Orphan Melvin; Daddy Peacebucks; Little Melvin Rooney; Smilin' Melvin; Upwind Johnson; Lil' Ab'r; Mammy Jokeum; Dick Tracing; Chief; Junior; Popcorn kids; Manduck The Magician; Loathar |
| 5 | The Railroad Timetable | text article | 1 | script: Frank Jacobs | |
| 6 | The Race Is On For The Super Guided Missile | comic story | 4 | script: Al Jaffee; pencils: Al Jaffee, Jack Davis, Wally Wood; inks: Al Jaffee, Jack Davis, Wally Wood | Gallup; Kerbang; Blitz; Pick; Back; Buck Roger; Waldo; Zork Argh; Dashkin; Propelnik; Schmidt; Beelzebub; Buck Rojinikoff; Plotkin; Watchova |
| 7 | Future TV Ad | comic story | 2 | script: Don Martin; pencils: Don Martin; inks: Don Martin | Charlie; Bill |
| 8 | Orson Bean's "The Two Chinese Fellas Who Go To An American Restaurant" Routine | comic story | 4 | script: Orson Bean; pencils: Wally Wood; inks: Wally Wood | Orson Bean |
| 9 | Scenes We'd Like To See: The Woodsman Who Failed To Save The Girl | comic story | 1 | pencils: Phil Interlandi; inks: Phil Interlandi | |
| 10 | Motorist Beware! | comic story | 2 | script: H. Goldstein; pencils: Bob Clarke; inks: Bob Clarke | |
| 11 | Field & Scream | comic story | 5 | pencils: Jack Davis; inks: Jack Davis | Lance Sturdley; Irv Blintz; Milton Forbisher; Lancelot Borscht-Bagel; Ozgood Z'Beard; Elmo Klunk; Walt Goober; Fenwick Furd |
| 12 | Alfred E. Neuman Answers Your Questions | comic story | 1 | pencils: Don Martin; inks: Don Martin | |
| 13 | Kovacs' Strangely Believe It! | comic story | 2 | script: Ernie Kovacs; pencils: Wally Wood; inks: Wally Wood; letters: Wally Wood | |
| 14 | Make Your Own Love-Story Comic | comic story | 2 | pencils: Jack Kamen; inks: Jack Kamen | |
| 15 | Scenes We'd Like To See: Escaping The Cannibals | comic story | 1 | pencils: Phil Interlandi; inks: Phil Interlandi | |
| 16 | Future Drive-Ins | comic story | 3 | pencils: Bob Clarke; inks: Bob Clarke | |
| 17 | The Truth About Cowboys | comic story | 4 | script: Henry Morgan; pencils: Wally Wood; inks: Wally Wood | Henry Morgan |
| 18 | New Designs In Television Sets | comic story | 2 | pencils: Jack Davis; inks: Jack Davis | |
| 19 | MAD Establishes An...Old Comic-Strip Characters' Home | text article | 2 | pencils: Wally Wood; inks: Wally Wood | Barnaby, Batman, Barney Baxter, Buster Brown, Big Chief Wahoo, Denny Colt, Dickie Dare, Eustace P. Dolan, Flyin' Jenny, Bruce Gentry First, Dick Grayson, Ignatz Mouse, Krazy Kat, Little Nemo |
| 20 | The Steve Allan Story | comic story | 5 | pencils: Bob Clarke; inks: Bob Clarke | Elvis Presley |
| 21 | Alfred E. Neuman Answers Your Questions | comic story | 1 | pencils: Don Martin; inks: Don Martin | Alfred E. Neuman |
| 22 | Mr. Science | comic story | 3 | script: Bob Elliott, Ray Goulding; pencils: Mort Drucker; inks: Mort Drucker | Mr. Science; Jimmy; Bob Elliott; Ray Goulding |
| 23 | Scenes We'd Like To See: The Fighter Who Didn't Rally | comic story | 1 | pencils: Phil Interlandi; inks: Phil Interlandi | |
| 24 | Modern Furniture | comic story | 4 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | Dave Berg |
| 25 | MAD Bubble Gum Cards | comic story | 2 | pencils: Jack Davis; inks: Jack Davis | Smedley van Sturdley; Milton Forbisher; Stanley Henkledorf; Walter N. Goober; Beauregard Bordon |
| 26 | What's Happened To Sports Magazines? | comic story | 4 | pencils: Bob Clarke; inks: Bob Clarke | Duke Snyder |
| 27 | MAD Tickets | text article | 1 | script: Frank Jacobs; pencils: George Woodbridge; inks: George Woodbridge | |
| 28 | Katchandhammer Kids! | comic story | 8 | script: Harvey Kurtzman; pencils: Will Elder; inks: Will Elder | Hans Katchandhammer; Feetz Katchandhammer; Der Kapitan; Inspektor; boat company man; Mamma |
| 29 | The "Night People" vs. "Creeping Meatballism" | comic story | 4 | script: Jean Shepherd; pencils: Wally Wood; inks: Wally Wood | |
| 30 | Scenes We'd Like To See: The Day of The Big Race | comic story | 1 | pencils: Phil Interlandi; inks: Phil Interlandi | |
| 31 | Future TV Ads | comic story | 2 | script: Don Martin; pencils: Don Martin; inks: Don Martin | George; Harriet |
| 32 | Wrestling | comic story | 10 | pencils: Jack Davis; inks: Jack Davis | Gomez Addams, Morticia Addams, Pugsley Addams, Frankenstein's monster |
| 33 | Free Fall Ferris | comic story | 3 | script: Jerry DeFuccio; pencils: Wallace Wood; inks: Wallace Wood | Free Fall Ferris |
| 34 | Pitchers and Poachers | comic story | 1 | letters: typeset | |
| 35 | Tom Lehrer Sings | text article | 3 | script: Tom Lehrer; pencils: George Woodbridge; inks: George Woodbridge | Tom Lehrer |
| 36 | Alfred E. Neuman Answers Your Questions | comic story | 1 | pencils: Don Martin; inks: Don Martin | |
| 37 | Wedding Album | comic story | 4 | pencils: Wally Wood; inks: Wally Wood | Wally Balloo |
| 38 | Kovacs' Strangely Believe It! | comic story | 2 | script: Ernie Kovacs; pencils: Wallace Wood; inks: Wally Wood; letters: Wally Wood | |
| 39 | Scenes We'd Like To See: The Last Minute Pardon | comic story | 1 | pencils: Joe Orlando; inks: Joe Orlando | |
| 40 | Yul Brynner Used Volatilis...Then He Took A Shower | comic story | 1 | pencils: Kelly Freas; inks: Kelly Freas | Yul Brynner |
| 41 | Nobody Asked Us, But; Purloined Proverbs Ascribed to Popular People; Fictitious Want Ads Placed By Famous Folk; Jobs We'd Like To Have; Meaningless Musings While Munching Miltown | text article | 0 | script: Arnie Rosen, Coleman Jacoby | |
| 42 | Seems Like Somebody Always Butts In When You Talk About...Winsten | comic story | 1 | pencils: Larry Maleman; inks: Larry Maleman; colors: Larry Maleman | Nick Megliola (postman); Jerry DeFuccio |