| 0 | Cover A | cover | 1 | pencils: Gabriel Rodriguez; inks: Gabriel Rodriguez | Mr. Spock; Optimus Prime; Dr. Peter Venkman |
| 1 | Recap | recap | 1 | pencils: John K. Snyder III, Gabriel Rodriguez, Ashley Wood; inks: John K. Snyder III, Gabriel Rodriguez, Ashley Wood; colors: Jason Wright, Ashley Wood | CVO [Covert Vampiric Operations; Benny the Smith; Britt; Bools; Cross; Overmars] |
| 2 | - | comic story | 32 | script: Dan Abnett, Andy Lanning; pencils: David Messina, Elena Casagrande; inks: Gaetano Carlucci, Elena Casagrande, Claudia Balboni; colors: ScarletGothica; letters: Robbie Robbins | CVO [Covert Vampiric Operations; Benny the Smith; Britt; Bools; Cross; Nikodemus; Overmars]; Wade; Noble (hallucination); Kathryn (hallucination); The Undermind; Scibot-21 |
| 3 | The Infestation Has Just Begun! | promo (ad from the publisher) | 1 | | |
| 4 | Sneak Peak: Tranformers: Infestation #1 | promo (ad from the publisher) | 2 | script: Dan Abnett, Andy Lanning; pencils: Nick Roche; inks: Nick Roche; colors: Joana Lafuente; letters: Robbie Robbins; editing: Andy Schmidt, Bobby Curnow | Galvatron; Optimus Prime; Bumblebee; Kup; Prowl; Wheeljack; Major Spike Witwicky |
| 5 | Cover Previews - The Transformers: Infestation #1 and #2 | promo (ad from the publisher) | 1 | pencils: Nick Roche; inks: Nick Roche; colors: Joana Lafuente | Optimus Prime; Bumblebee; Galvatron |
| 6 | Cover Previews - Star Trek: Infestation #1 and #2 | promo (ad from the publisher) | 1 | pencils: John K. Snyder III, Casey Maloney, Gordon Purcell, Gabriel Rodriguez; inks: John K. Snyder III, Casey Maloney, Gordon Purcell, Gabriel Rodriguez; colors: Jason Wright, Luis Antonio Delgado | Admiral James T. Kirk; Mr. Spock; Bones [Dr. Leonard McCoy] |
| 7 | Sneak Peak: Star Trek: Infestation #1 | promo (ad from the publisher) | 2 | script: Scott Tipton, David Tipton; pencils: Casey Maloney, Gary Erskine; inks: Gary Erskine; colors: Luis Antonio Delgado; letters: Chris Mowry; editing: Tom Waltz, Bobby Curnow | Admiral James T. Kirk; Mr. Spock; Bones [Dr. Leonard McCoy]; Barnes; Emigh; Padilla |
| 8 | Sneak Peak: G.I. Joe: Infestation #1 | promo (ad from the publisher) | 2 | script: Mike Raicht; pencils: Giovanni Timpano; inks: Giovanni Timpano; colors: J. Brown; letters: Chris Mowry; editing: Andy Schmidt, Bobby Curnow | Baroness |
| 9 | Cover Previews - G.I. Joe: Infestation #1 & #2 | promo (ad from the publisher) | 1 | pencils: Giovanni Timpano; inks: Giovanni Timpano; colors: J. Brown | Baroness; Psyche Out |
| 10 | Cover Previews - Ghostbusters: Infestation #1 & #2 | promo (ad from the publisher) | 1 | | Dr. Egon Spengler; Dr. Peter Venkman; Dr. Raymond Stantz; Winston Zeddemore |
| 11 | Sneak Peak: Ghostbusters: Infestation #1 | promo (ad from the publisher) | 2 | script: Erik Burnham; pencils: Kyle Hotz; inks: Kyle Hotz | Dr. Egon Spengler; Winston Zeddemore |
| 12 | Infestation Checklist | promo (ad from the publisher) | 1 | | |