| 0 | - | cover | 1 | pencils: Phil Moy; inks: Phil Moy; colors: Jason Lewis | |
| 1 | - | blank page(s) | 1 | | |
| 2 | The Powerpuff Girls Classics Volume 3 | credits, title page | 1 | letters: typeset | |
| 3 | - | credits, title page | 1 | letters: typeset | |
| 4 | - | cover reprint (on interior page) | 1 | pencils: Phil Moy; inks: Phil Moy | |
| 5 | Shutter Thug | comic story | 22 | script: Sean Carolan, Jennifer Moore; pencils: Phil Moy; inks: Phil Moy; colors: Dave Tanguay; letters: Ryan Cline; editing: Harvey Richards, Joan Hilty | |
| 6 | - | cover reprint (on interior page) | 1 | pencils: Phil Moy; inks: Phil Moy | Blossom; Buttercup; Bubbles; Abominable Snowman |
| 7 | Snow Day | comic story | 22 | script: Abby Denson; pencils: Ricardo Garcia Fuentes; inks: Mike DeCarlo; colors: Dave Tanguay; letters: Ryan Cline; editing: Harvey Richards, Joan Hilty | Buttercup; Bubbles; Blossom; Professor Utonium; Mayor; Sara Bellum; Abominable Snowman |
| 8 | Paranoid Puffs! | cover reprint (on interior page) | 1 | pencils: Phil Moy; inks: Phil Moy; letters: Todd Klein | Blossom; Bubbles; Buttercup; Professor Utonium |
| 9 | Paranoid Puffs | comic story | 16 | script: Bobbi JG Morse; pencils: Cindy Morrow; inks: Mike DeCarlo; colors: Dave Tanguay; letters: Ryan Cline; editing: Harvey Richards, Joan Hilty | Buttercup; Blossom; Bubbles; Professor Utonium; Mojo Jojo |
| 10 | Beat the Stuffings | comic story | 6 | script: Frank Strom; pencils: Stephanie Gladden; inks: Mike DeCarlo; colors: Dave Tanguay; letters: Ryan Cline; editing: Harvey Richards, Joan Hilty | Bubbles; Blossom; Buttercup; Professor Utonium; Gangreen Gang [Ace; Big Billy; Snake; Grubber; Li'l Arturo]; Mayor |
| 11 | Goo vs. Good! | cover reprint (on interior page) | 1 | pencils: Phil Moy; inks: Phil Moy; colors: Dave Tanguay; letters: Todd Klein | |
| 12 | Gone Squiggly | comic story | 22 | script: John Rozum; pencils: Phil Moy; inks: Phil Moy; colors: Dave Tanguay; letters: Ryan Cline; editing: Harvey Richards, Joan Hilty | |
| 13 | It's a Shore Thing! | cover reprint (on interior page) | 1 | pencils: Phil Moy; inks: Phil Moy; colors: Dave Tanguay; letters: Todd Klein | Bubbles; Blossom; Buttercup; Professor Utonium |
| 14 | Shore Thing! | comic story | 12 | script: Abby Denson; pencils: Ricardo Garcia Fuentes; inks: Mike DeCarlo; colors: Dave Tanguay; letters: Jenna Garcia; editing: Harvey Richards, Joan Hilty | Buttercup; Bubbles; Blossom; Professor Utonium; Princess Morbucks; Daddy Morbucks (cameo) |
| 15 | Powerpuff Picasso | comic story | 10 | script: Trina Robbins; pencils: Bill Alger; inks: Mike DeCarlo; colors: Dave Tanguay; letters: Jenna Garcia; editing: Harvey Richards, Joan Hilty | Blossom; Buttercup; Bubbles; Mojo Jojo; Mitch Mitchelson |
| 16 | Hell Toupee | cover reprint (on interior page) | 1 | pencils: Phil Moy; inks: Phil Moy; letters: Todd Klein | Bubbles; Buttercup; Blossom; Sedusa |
| 17 | Hell Toupee | comic story | 12 | script: Trina Robbins; pencils: Ricardo Garcia Fuentes; inks: Mike DeCarlo; colors: Dave Tanguay; letters: Ryan Cline; editing: Harvey Richards, Joan Hilty | Buttercup; Blossom; Bubbles; Professor Utonium; Sedusa [Madge]; Mayor; Sara Bellum |
| 18 | Five Green Vandals | comic story | 10 | script: Abby Denson; pencils: Ricardo Garcia Fuentes; inks: Andrew Pepoy; colors: Dave Tanguay; letters: Ryan Cline; editing: Harvey Richards, Joan Hilty | Blossom; Buttercup; Bubbles; Gangreen Gang [Ace; Big Billy; Snake; Grubber; Li'l Arturo]; Mayor |
| 19 | - | blank page(s) | 1 | | |
| 20 | - | illustration | 1 | letters: typeset | |