| 0 | The Facts of Life | cover | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Invincible [Mark Grayson]; Amber Bennett; Angstrom Levy; Mauler Twins; Allan the Alien; Darkwing; reaniman |
| 1 | - | illustration | 1 | pencils: Ryan Ottley; inks: Ryan Ottley | Invincible [Mark Grayson] |
| 2 | The Facts of Life | credits, title page | 3 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree; letters: Rus Wooton | Invincible [Mark Grayson] |
| 3 | - | foreword, introduction, preface, afterword | 2 | script: Mike Wieringo | |
| 4 | Chapter One | cover reprint (on interior page) | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Invincible [Mark Grayson]; reaniman |
| 5 | - | comic story | 22 | script: Robert Kirkman; pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree; letters: Rus Wooton | Invincible [Mark Grayson]; Atom Eve; Angstrom Levy; Mauler Twins; Art Rosenbaum; Debbie Grayson; William Clockwell; Rick Sheridan; D.A. Sinclair; Amber Bennett; reaniman |
| 6 | Amber Bennett | illustration | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Amber Bennett |
| 7 | Chapter Two | cover reprint (on interior page) | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Invincible [Mark Grayson]; Darkwing [Night Boy] |
| 8 | - | comic story | 20 | script: Robert Kirkman; pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree; letters: Rus Wooton | Darkwing [Night Boy]; Guardians of the Globe [Black Samson; Bulletproof; Robot]; Donald Ferguson; Cecil Stedman; Immortal; Invincible [Mark Grayson]; Rick Sheridan; William Clockwell; Angstrom Levy; Mauler Twins; |
| 9 | Darkwing | illustration | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Invincible [Mark Grayson]; Darkwing [Night Boy] |
| 10 | Chapter Three | cover reprint (on interior page) | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Invincible [Mark Grayson]; Amber Bennett |
| 11 | - | comic story | 20 | script: Robert Kirkman; pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree; letters: Rus Wooton | Invincible [Mark Grayson]; Rick Sheridan; William Clockwell; Amber Bennett; Jannie; Bridget; D.A. Sinclair; Atom Eve; Mauler Twins; Angstrom Levy; Debbie Grayson; Art Rosenbaum; Guardians of the Globe [Robot; Monster Girl]; Cecil Stedman; Shapesmith; Reanimen |
| 12 | Robot; Monster Girl | illustration | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Robot; Monster Girl |
| 13 | Chapter Four | cover reprint (on interior page) | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Invincible [Mark Grayson]; Art Rosenbaum; Omni-Man; Debbie Grayson; Amber Bennett; Cecil Stedman; William Clockwell; Atom Eve; Donald Ferguson |
| 14 | - | comic story | 12 | script: Robert Kirkman; pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree; letters: Rus Wooton | Invincible [Mark Grayson]; Amber Bennett; Omni-Man (flashback); Flaxans (flashback); Atom Eve (flashback); Immortal (flashback); Cecil Stedman (flashback); Reaniman (flashback) |
| 15 | Omni-Man | illustration | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Omni-Man; Immortal |
| 16 | Chapter Five | cover reprint (on interior page) | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Allen the Alien |
| 17 | This Missive, This Machination! | comic story | 20 | script: Robert Kirkman; pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree; letters: Rus Wooton | Allen the Alien; Invincible [Mark Grayson]; Amber Bennett; Thaedus; Coalition of Planets; Telia; Viltrumite Empire [Lucan; others] |
| 18 | - | illustration | 1 | script: Robert Kirkman; letters: Rus Wooton | |
| 19 | Chapter Six | cover reprint (on interior page) | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Invincible [Mark Grayson] |
| 20 | - | comic story | 20 | script: Robert Kirkman; pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree; letters: Rus Wooton | Invincible [Mark Grayson]; Art Rosenbaum; Debbie Grayson; William Clockwell; Angstrom Levy; Mauler Twin; Guardians of the Globe [Monster Girl; Shrinking Ray; Rex Splode; Dupli-Kate; Robot; Bulletproof; Immortal] |
| 21 | Mauler Twins | illustration | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Mauler Twins |
| 22 | Origins | illustration | 1 | pencils: Khary Randolph; inks: Khary Randolph; colors: Khary Randolph | Atom Eve |
| 23 | At Long Last-- The Secret Origin of Monster Girl! | comic story | 3 | script: Robert Kirkman; pencils: Todd Nauck; inks: Todd Nauck; colors: Bill Crabtree; letters: Rus Wooton | Monster Girl |
| 24 | At Long Last-- The Secret Origin of Rex Splode! | comic story | 2 | script: Robert Kirkman; pencils: Matthew Roberts; inks: Matthew Roberts; colors: Bill Crabtree; letters: Rus Wooton | Rex Splode; Mrs. Sloan; Mr. Sloan; Director Radcliffe |
| 25 | At Long Last-- The Secret Origin of The Immortal! | comic story | 1 | script: Robert Kirkman; pencils: Cory Walker; inks: Cory Walker; colors: Bill Crabtree; letters: Rus Wooton | Immortal; Dupli-Kate |
| 26 | At Long Last-- The Secret Origin of Dupli-Kate! | comic story | 3 | script: Robert Kirkman; pencils: Joshua Luna; inks: Joshua Luna; colors: Joshua Luna; letters: Rus Wooton | Dupli-Kate; Multi-Paul; Fung Cha; Tsing Cha |
| 27 | At Long Last-- The Secret Origin of Atom Eve! | comic story | 3 | script: Robert Kirkman; pencils: Khary Randolph; inks: Khary Randolph; colors: Kanila Tripp; letters: Rus Wooton | Atom Eve; Adam Wilkins; Betsy Wilkins; Elias Brandyworth; Dr. Rodgers; Steven Erickson |
| 28 | Monster Girl | illustration | 1 | pencils: Todd Nauck; inks: Todd Nauck; colors: Bill Crabtree | Monster Girl |
| 29 | Sketchbook | illustration | 22 | script: Robert Kirkman; pencils: Ryan Ottley, Cory Walker; inks: Ryan Ottley, Cory Walker; colors: Ryan Ottley, Cory Walker | |
| 30 | Pick Up These Great Books Also From Robert Kirkman! | promo (ad from the publisher) | 1 | pencils: various; inks: various; colors: various; letters: typeset | |
| 31 | - | illustration | 1 | pencils: Ryan Ottley; inks: Ryan Ottley | Invincible [Mark Grayson] |
| 32 | Fighting Supervillains. Saving the World. Keeping a Secret Identity. | recap | 1 | pencils: Ryan Ottley; inks: Ryan Ottley; colors: Bill Crabtree | Invincible [Mark Grayson]; Amber Bennett |