| 0 | - | cover | 1 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Marcio Menyz | Green Goblin, Norman Osborn, Peter Parker, Spider-Goblin |
| 1 | - | promo (ad from the publisher) | 1 | letters: typeset | |
| 2 | Title Page and Credits | credits, title page | 3 | pencils: Ed McGuinness; inks: Mark Farmer | |
| 3 | #50 Variant | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Scott Hanna; colors: Dean White | Green Goblin, Norman Osborn, Peter Parker, Spider-Man |
| 4 | 50 | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Marcio Menyz | Green Goblin, Norman Osborn, Peter Parker, Spider-Man |
| 5 | - | comic story | 40 | script: Zeb Wells; pencils: Ed McGuinness; inks: Mark Farmer; colors: Marcio Menyz, Erick Arciniega; letters: VC's Joe Caramagna | Curt Connors, Green Goblin, Dr. Ashley Kafka, Kraven the Hunter, Sergei Kravinoff, Norman Osborn, Peter Parker, Queen Goblin, Doug Siravanta, Spider-Man, Ultra Living Brain, Vermin, Ultra Living Brain, Edward Whelan |
| 6 | Epilogue | comic story | 3 | script: Zeb Wells; pencils: Todd Nauck; inks: Todd Nauck; colors: Rachelle Rosenberg; letters: VC's Joe Caramagna | Curt Connors, Ultra Living Brain |
| 7 | 51 | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Todd Nauck | Quentin Beck, Max Dillon, Doctor Octopus, Electro, Kraven the Hunter, Sergei Kravinoff, Flint Marko, Mysterio, Otto Octavius, Peter Parker, Sandman, Spider-Man, Adrian Toomes, The Vulture |
| 8 | - | comic story | 20 | script: Zeb Wells; pencils: Ed McGuinness, Todd Nauck; inks: Mark Farmer, Todd Nauck, Cliff Rathburn, Wade von Grawbadger; colors: Marcio Menyz, Erick Arciniega, Bryan Valenza; letters: VC's Joe Caramagna | Quentin Beck, Captain America, Chasm, Carol Danvers, Max Dillon, Doctor Octopus, Doctor Strange, Jessica Drew, Electro, Janine Godbe, Green Goblin, Hallows' Eve, Kamala Khan, Kraven the Hunter |
| 9 | Epilogue | comic story | 2 | script: Zeb Wells; pencils: Ed McGuinness, Todd Nauck; inks: Mark Farmer, Todd Nauck, Cliff Rathburn, Wade von Grawbadger; colors: Marcio Menyz, Erick Arciniega, Bryan Valenza; letters: VC's Joe Caramagna | Curt Connors, J. Jonah Jameson, Doug Siravanta, Ultra Living Brain |
| 10 | 52 | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Marcio Menyz | Peter Parker, Spider-Goblin |
| 11 | - | comic story | 20 | script: Zeb Wells; pencils: Ed McGuinness, Todd Nauck; inks: Mark Farmer, Wade von Grawbadger, Todd Nauck; colors: Marcio Menyz, Erick Arciniega; letters: VC's Joe Caramagna | Chasm, Curt Connors, Green Goblin, J. Jonah Jameson, Kamala Khan, Kraven the Hunter, Sergei Kravinoff, Ms. Marvel, Norman Osborn, Peter Parker, Ben Reilly, Rek-Rap, Doug Siravanta, Spider-Goblin |
| 12 | 53 | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Marcio Menyz | Quentin Beck, Max Dillon, Doctor Octopus, Electro, Kraven the Hunter, Sergei Kravinoff, Flint Marko, Mysterio, Otto Octavius, Peter Parker, Sandman, Spider-Goblin, Adrian Toomes, The Vulture |
| 13 | - | comic story | 20 | script: Zeb Wells; pencils: Todd Nauck, Ed McGuinness; inks: Todd Nauck, Wade von Grawbadger; colors: Marcio Menyz; letters: VC's Joe Caramagna | Quentin Beck, Curt Connors, Max Dillon, Doctor Octopus, Electro, Green Goblin, J. Jonah Jameson, Kamala Khan, Kraven the Hunter, Sergei Kravinoff, Flint Marko, Ms. Marvel, Mysterio, Otto Octavius |
| 14 | #54 Variant | cover reprint (on interior page) | 1 | pencils: Yasmine Putri; inks: Yasmine Putri; colors: Yasmine Putri | Peter Parker, Spider-Man |
| 15 | #54 | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Marcio Menyz | Green Goblin, Norman Osborn, Peter Parker, Spider-Goblin |
| 16 | - | comic story | 22 | script: Zeb Wells; pencils: Ed McGuinness; inks: Mark Farmer, Mark Morales, Wade von Grawbadger, Ed McGuinness; colors: Marcio Menyz; letters: VC's Joe Caramagna | The Burglar, Curt Connors, Green Goblin, J. Jonah Jameson, Kamala Khan, Kraven the Hunter, Sergei Kravinoff, Morlun, Ms. Marvel, Norman Osborn, Peter Parker, Ben Parker, Red Goblin, Rek-Rap |
| 17 | - | credits, title page | 1 | letters: typeset | |
| 18 | Cat-Nipped! | comic story | 8 | script: Marv Wolfman; pencils: Terry Dodson; inks: Rachel Dodson; colors: Terry Dodson; letters: VC's Joe Caramagna | Black Cat, Felicia Hardy, Peter Parker, Spider-Man |
| 19 | Time to Make the Doughnuts | comic story | 8 | script: Nikesh Shukla; pencils: ChrisCross; inks: ChrisCross; colors: Andrew Dalhouse; letters: VC's Joe Caramagna | Boomerang, Mac Gargan, Fred Myers, Peter Parker, Scorpion, Spider-Man |
| 20 | Don't Thing Thrice, It's All Right | comic story | 5 | script: Lee Gatlin; pencils: Lee Gatlin; inks: Lee Gatlin; colors: Lee Gatlin; letters: Lee Gatlin | Bruce Banner, Black Panther, Black Widow, Captain America, Daredevil, Ben Grimm, Hulk, Iron Man, Matt Murdock, Thor Odinson, Peter Parker, Professor X, Rhino, Steve Rogers |
| 21 | Secrets | comic story | 4 | script: Joe Kelly; pencils: Juan Ferreyra; inks: Juan Ferreyra; colors: Juan Ferreyra; letters: VC's Joe Caramagna | Doctor Strange, Peter Parker, Spider-Man, Stephen Strange |
| 22 | #50 Variant | cover reprint (on interior page) | 0.25 | pencils: Greg Capullo; inks: Greg Capullo; colors: FCO Plascencia | Peter Parker, Spider-Man |
| 23 | #50 Black Costume Variant | cover reprint (on interior page) | 0.25 | pencils: Iban Coello; inks: Iban Coello; colors: Jesus Aburtov | Peter Parker, Spider-Man |
| 24 | #50 Variant | cover reprint (on interior page) | 0.25 | pencils: John Romita Sr.; inks: John Romita Sr.; colors: Edgar Delgado | Peter Parker, Spider-Man |
| 25 | #50 Variant | cover reprint (on interior page) | 0.25 | pencils: Nick Bradshaw; inks: Nick Bradshaw; colors: Rachelle Rosenberg | Quentin Beck, Max Dillon, Doctor Octopus, Electro, Kraven the Hunter, Sergei Kravinoff, Flint Marko, Mysterio, Otto Octavius, Peter Parker, Sandman, Spider-Man, Adrian Toomes, The Vulture |
| 26 | #50 Negative Space Variant | cover reprint (on interior page) | 0.25 | pencils: John Tyler Christopher; inks: John Tyler Christopher; colors: John Tyler Christopher | Peter Parker, Spider-Man |
| 27 | #51 Foil Variant | cover reprint (on interior page) | 0.25 | pencils: David Nakayama; inks: David Nakayama; colors: David Nakayama | Peter Parker, Spider-Man |
| 28 | #51 Variant | cover reprint (on interior page) | 0.5 | pencils: Tony Harris; inks: Tony Harris; colors: Tony Harris | Peter Parker, Spider-Man |
| 29 | #51 Big Marvel Variant | cover reprint (on interior page) | 0.25 | pencils: Skottie Young; inks: Skottie Young; colors: Skottie Young | |
| 30 | #51 Big Marvel Black & White Variant | cover reprint (on interior page) | 0.25 | pencils: Skottie Young; inks: Skottie Young | |
| 31 | #52 Big Marvel Variant | cover reprint (on interior page) | 0.25 | pencils: Skottie Young; inks: Skottie Young; colors: Skottie Young | |
| 32 | #52 Big Marvel Black & White Variant | cover reprint (on interior page) | 0.25 | pencils: Skottie Young; inks: Skottie Young | |
| 33 | #52 Variant | cover reprint (on interior page) | 0.25 | pencils: Adi Granov; inks: Adi Granov; colors: Adi Granov | Peter Parker, Spider-Man |
| 34 | #52 Pride Allies Variant | cover reprint (on interior page) | 0.25 | pencils: Davi Go; inks: Davi Go; colors: Davi Go | Jean-Paul Beaubier, Northstar, Peter Parker, Spider-Man |
| 35 | #52 Variant | cover reprint (on interior page) | 0.25 | pencils: Pablo Villalobos; inks: Pablo Villalobos; colors: Pablo Villalobos | Black Cat, Felicia Hardy |
| 36 | #53 Variant | cover reprint (on interior page) | 0.25 | pencils: Russell Dauterman; inks: Russell Dauterman; colors: Russell Dauterman | Peter Parker, Spider-Man |
| 37 | #53-54 Connecting Variants | cover reprint (on interior page) | 0.5 | pencils: Gabriele Dell'Otto; inks: Gabriele Dell'Otto; colors: Gabriele Dell'Otto | Quentin Beck, Max Dillon, Doctor Octopus, Electro, Kraven the Hunter, Sergei Kravinoff, Flint Marko, Mysterio, Otto Octavius, Peter Parker, Sandman, Spider-Man, Adrian Toomes, The Vulture |
| 38 | #54 Variant | cover reprint (on interior page) | 0.25 | pencils: Federica Mancin; inks: Federica Mancin; colors: Edgar Delgado | Peter Parker, Spider-Man |
| 39 | #54 Deadpool Kills the Marvel Universe Variant | cover reprint (on interior page) | 0.25 | pencils: Javier Garrón; inks: Javier Garrón; colors: Jesus Aburtov | Deadpool, Peter Parker, Spider-Man, Wade Wilson |
| 40 | - | promo (ad from the publisher) | 1 | letters: typeset | |
| 41 | - | promo (ad from the publisher) | 1 | letters: typeset | |