| 0 | - | cover | 1 | pencils: Alex Ross; inks: Alex Ross; colors: Alex Ross | Peter Parker, Spider-Man |
| 1 | Credits Page | credits, title page | 1 | letters: typeset | |
| 2 | - | cover reprint (on interior page) | 1 | pencils: Alex Ross; inks: Alex Ross; colors: Alex Ross | Peter Parker, Spider-Man |
| 3 | Worldwide | comic story | 31 | script: Dan Slott; pencils: Giuseppe Camuncoli; inks: Cam Smith; colors: Marte Gracia; letters: VC's Joe Caramagna | Hobie Brown, Phillip Chang, The Living Brain, Anna Maria Marconi, Mockingbird, Bobbi Morse, Peter Parker, Spider-Man |
| 4 | Breaking Bad | comic story | 5 | script: Robbie Thompson; pencils: Stacey Lee; inks: Stacey Lee; colors: Ian Herring; letters: VC's Travis Lanham | Black Cat, Felicia Hardy, Cindy Moon, Silk |
| 5 | What to Expect | comic story | 5 | script: Dennis Hopeless; pencils: Javier Rodríguez; inks: Álvaro López; colors: Javier Rodríguez; letters: VC's Travis Lanham | Captain Marvel, Carol Danvers, Lorina Dodson, Jessica Drew, Spider-Woman, White Rabbit |
| 6 | The Cellar | comic story | 7 | script: Dan Slott, Christos Gage; pencils: Paco Diaz; inks: Paco Diaz; colors: Israel Silva; letters: VC's Joe Caramagna | Lorina Dodson, Miles Morales, Spider-Man, White Rabbit |
| 7 | - | cover reprint (on interior page) | 1 | pencils: Alex Ross; inks: Alex Ross; colors: Alex Ross | Peter Parker, Spider-Man |
| 8 | Water Proof | comic story | 20 | script: Dan Slott; pencils: Giuseppe Camuncoli; inks: Cam Smith; colors: Marte Gracia; letters: VC's Joe Caramagna | Hobie Brown, Nick Fury Jr., Jackal, Marcus Johnson, Mockingbird, Bobbi Morse, Peter Parker, Prowler, Rhino, Spider-Man, Aleksei Sytsevich, Miles Warren |
| 9 | - | cover reprint (on interior page) | 1 | pencils: Alex Ross; inks: Alex Ross; colors: Alex Ross | Human Torch, Peter Parker, Spider-Man, Johnny Storm |
| 10 | Friendly Fire | comic story | 20 | script: Dan Slott; pencils: Giuseppe Camuncoli; inks: Cam Smith; colors: Marte Gracia; letters: VC's Chris Eliopoulos | Nick Fury Jr., Human Torch, J. Jonah Jameson, Marcus Johnson, Mockingbird, Bobbi Morse, Harry Osborn, Norman Osborn, Peter Parker, Spider-Man, Johnny Storm |
| 11 | - | cover reprint (on interior page) | 1 | pencils: Alex Ross; inks: Alex Ross; colors: Alex Ross | Peter Parker, Spider-Man |
| 12 | High Priority | comic story | 21 | script: Dan Slott; pencils: Giuseppe Camuncoli; inks: Cam Smith; colors: Marte Gracia; letters: VC's Joe Caramagna | Hobie Brown, Curt Connors, Nick Fury Jr., Human Torch, Jackal, Marcus Johnson, Lizard, Mockingbird, Bobbi Morse, Norman Osborn, May Parker, Peter Parker, Prowler, Spider-Man |
| 13 | #1 Variant | cover reprint (on interior page) | 1 | pencils: Humberto Ramos; inks: Humberto Ramos; colors: Edgar Delgado | Peter Parker, Spider-Man |
| 14 | - | cover reprint (on interior page) | 1 | pencils: Alex Ross; inks: Alex Ross; colors: Alex Ross | Peter Parker, Spider-Man |
| 15 | Set in Stone | comic story | 20 | script: Dan Slott, Christos Gage; pencils: Giuseppe Camuncoli; inks: Cam Smith; colors: Marte Gracia; letters: VC's Joe Caramagna | Hobie Brown, Nick Fury Jr., Human Torch, Marcus Johnson, The Living Brain, Anna Maria Marconi, Mockingbird, Bobbi Morse, Peter Parker, Prowler, Spider-Man, Johnny Storm |
| 16 | The Spider's Corner with Petey P. | comic story | 2 | script: Anthony Holden; pencils: Anthony Holden; inks: Anthony Holden; colors: Jordie Bellaire; letters: Anthony Holden | Petey Parker; Aunt May; Rhino; Doctor Octopus; Venom; Kraven; Electro; Kingpin; Mysterio; Vulture; Doppelganger; Lizard |
| 17 | #1 Variant | cover reprint (on interior page) | 1 | pencils: Mark Bagley; inks: Andrew Hennessy; colors: Nolan Woodard | Peter Parker, Spider-Man |
| 18 | #1 Design Variant | cover reprint (on interior page) | 0.5 | pencils: Alex Ross; inks: Alex Ross; colors: Alex Ross | Peter Parker, Spider-Man |
| 19 | #1 Hip-Hop Variant | cover reprint (on interior page) | 0.5 | pencils: Mike Del Mundo; inks: Mike Del Mundo; colors: Mike Del Mundo | Beetle, Black Cat, Boomerang, Curt Connors, Felicia Hardy, J. Jonah Jameson, Martin Li, Janice Lincoln, Lizard, Flint Marko, Mister Negative, Cindy Moon, Fred Myers, Peter Parker |
| 20 | #2 Variant | cover reprint (on interior page) | 1 | pencils: Giuseppe Camuncoli; inks: Cam Smith; colors: Marte Gracia | Peter Parker, Spider-Man |
| 21 | #3 Variant | cover reprint (on interior page) | 1 | pencils: Gabriele Dell'Otto; inks: Gabriele Dell'Otto; colors: Gabriele Dell'Otto | Peter Parker, Spider-Man |