| 0 | - | cover | 1 | pencils: Jae Lee; inks: Jae Lee; colors: June Chung | Martin Li, Mister Negative, Peter Parker, Spider-Man |
| 1 | Title Page and Credits | credits, title page | 3 | pencils: Mateus Santolouco; inks: Mateus Santolouco; colors: Chris Sotomayor | |
| 2 | Lethal Legion | cover reprint (on interior page) | 1 | pencils: Tommy Lee Edwards; inks: Tommy Lee Edwards; colors: Tommy Lee Edwards | Absorbing Man, Crusher Creel, Grim Reaper, M'Baku, Man-Ape, Mister Hyde, Nekra, Eric Williams, Calvin Zabo |
| 3 | Part One | comic story | 22 | script: Frank Tieri; pencils: Mateus Santolouco; inks: Mateus Santolouco; colors: Chris Sotomayor; letters: VC's Chris Eliopoulos; editing: Jeanine Schaefer | Absorbing Man, Todd Arliss, Crusher Creel, Paul Pierre Duval, Mac Gargan, Grey Gargoyle, Grim Reaper, Hawkeye, Iron Patriot, Lester, M'Baku, Man-Ape, Mister Hyde, Nekra |
| 4 | Lethal Legion | cover reprint (on interior page) | 1 | pencils: Tommy Lee Edwards; inks: Tommy Lee Edwards; colors: Tommy Lee Edwards | Grim Reaper, Eric Williams, Simon Williams, Wonder Man |
| 5 | Part Two | comic story | 22 | script: Frank Tieri; pencils: Mateus Santolouco; inks: Mateus Santolouco; colors: Chris Sotomayor; letters: VC's Joe Sabino; editing: Jeanine Schaefer | Absorbing Man, Akihiro, Ares, Todd Arliss, Captain Marvel, Crusher Creel, Paul Pierre Duval, Mac Gargan, Grey Gargoyle, Grim Reaper, Hawkeye, Iron Patriot, Lester, Man-Bull |
| 6 | Lethal Legion | cover reprint (on interior page) | 1 | pencils: Tommy Lee Edwards; inks: Tommy Lee Edwards; colors: Tommy Lee Edwards | Absorbing Man, Crusher Creel, Grim Reaper, Iron Patriot, Mister Hyde, Nekra, Norman Osborn, Eric Williams, Simon Williams, Wonder Man, Calvin Zabo |
| 7 | Part Three | comic story | 22 | script: Frank Tieri; pencils: Mateus Santolouco; inks: Mateus Santolouco; colors: Chris Sotomayor; letters: VC's Joe Sabino; editing: Jeanine Schaefer | Absorbing Man, Akihiro, Todd Arliss, Crusher Creel, Paul Pierre Duval, Grey Gargoyle, Grim Reaper, Hawkeye, Iron Patriot, Lester, Mister Hyde, Ms. Marvel, Nekra, Norman Osborn |
| 8 | Zodiac | cover reprint (on interior page) | 1 | pencils: Nathan Fox; inks: Nathan Fox; colors: José Villarrubia | Zodiac |
| 9 | For the Sake of Mischief | comic story | 22 | script: Joe Casey; pencils: Nathan Fox; inks: Nathan Fox; colors: José Villarrubia; letters: Richard Starkings, Comicraft's Albert Deschesne; editing: Tom Brevoort | Dave Cannon, Human Torch, Manslaughter Marsdale, Norman Osborn, Peter Petruski, Johnny Storm, Trapster, Clown, Elliot Franklin |
| 10 | Zodiac | cover reprint (on interior page) | 1 | pencils: Nathan Fox; inks: Nathan Fox; colors: José Villarrubia | Zodiac |
| 11 | Ill-Gotten Gains | comic story | 22 | script: Joe Casey; pencils: Nathan Fox; inks: Nathan Fox; colors: José Villarrubia; letters: Comicraft's Albert Deschesne; editing: Tom Brevoort | Clint Barton, Dave Cannon, Human Torch, Invisible Woman, Manslaughter Marsdale, Norman Osborn, Peter Petruski, Hank Pym, Red Ronin, Ronin, Susan Storm Richards, Johnny Storm, Trapster, Wasp |
| 12 | Zodiac | cover reprint (on interior page) | 1 | pencils: Nathan Fox; inks: Nathan Fox; colors: José Villarrubia | Zodiac |
| 13 | Death's Finest Addiction | comic story | 22 | script: Joe Casey; pencils: Nathan Fox; inks: Nathan Fox; colors: José Villarrubia; letters: Comicraft's Albert Deschesne; editing: Tom Brevoort | Dave Cannon, Human Torch, Iron Patriot, Manslaughter Marsdale, Mister Fantastic, Ms. Marvel, Norman Osborn, Peter Petruski, Red Ronin, Reed Richards, Karla Sofen, Johnny Storm, Trapster, Clown |
| 14 | Mister Negative | cover reprint (on interior page) | 1 | pencils: Jae Lee; inks: Jae Lee; colors: June Chung | Martin Li, Mister Negative, Peter Parker, Spider-Man |
| 15 | Previously in Amazing Spider-Man... | recap | 1 | script: Tom Brennan | |
| 16 | The Last Stand of Mr. Negative | comic story | 22 | script: Fred Van Lente; pencils: Gianluca Gugliotta; inks: Andy Lanning, Kris Justice; colors: Ronda Pattison, Andres Mossa; letters: Dave Lanphear; editing: Stephen Wacker | The Answer, Betty Brant, Donald Callahan, Lorina Dodson, Hammerhead, The Hood, Steven Hudak, Edward Lansky, Martin Li Origin, Lightmaster, Mister Negative Origin, Aaron Nicholson, Johnathon Ohnn, May Parker |
| 17 | Mister Negative | cover reprint (on interior page) | 1 | pencils: Jae Lee; inks: Jae Lee; colors: June Chung | Peter Parker, Spider-Man |
| 18 | Battle for Chinatown | comic story | 22 | script: Fred Van Lente; pencils: Gianluca Gugliotta; inks: Gianluca Gugliotta; colors: Ronda Pattison; letters: Dave Lanphear; editing: Stephen Wacker | The Answer, Betty Brant, Donald Callahan, Lorina Dodson, Hammerhead, The Hood, Steven Hudak, Iron Patriot, Edward Lansky, Martin Li, Lightmaster, Mister Negative, Aaron Nicholson, Johnathon Ohnn |
| 19 | Mister Negative | cover reprint (on interior page) | 1 | pencils: Jae Lee; inks: Jae Lee; colors: June Chung | Martin Li, Mister Negative, Peter Parker, Spider-Man |
| 20 | Negative Reinforcement | comic story | 22 | script: Fred Van Lente; pencils: Gianluca Gugliotta; inks: Gianluca Gugliotta; colors: Ronda Pattison, Andres Mossa, Antonio Fabela; letters: Dave Lanphear; editing: Stephen Wacker | The Answer, Betty Brant, Donald Callahan, Lorina Dodson, The Hood, Edward Lansky, Martin Li, Lightmaster, Mister Negative, Aaron Nicholson, Johnathon Ohnn, Norman Osborn, Peter Parker, Parker Robbins |
| 21 | Dark Reign | cover reprint (on interior page) | 1 | pencils: Khoi Pham; inks: Khoi Pham; colors: John Rauch | Attuma, Daniel Berkhart, Spymaster |
| 22 | Made Men: Spymaster | comic story | 8 | script: Frank Tieri; pencils: Khoi Pham; inks: Khoi Pham; colors: John Rauch; letters: VC's Rus Wooton, VC's Joe Caramagna; editing: Tom Brevoort | Norman Osborn, Spymaster |
| 23 | Made Men: Attuma | comic story | 8 | script: Frank Tieri; pencils: Rafa Sandoval; inks: Roger Bonet Martinez; colors: Antonio Fabela; letters: VC's Rus Wooton, VC's Joe Caramagna; editing: Tom Brevoort | Attuma, Doctor Doom, Victor Von Doom, Ben Grimm, Invisible Woman, Mister Fantastic, Namor, Robert Reynolds, Reed Richards, The Sentry, Susan Storm Richards, Sub-Mariner, The Thing |
| 24 | Made Men: Jack O'Lantern | comic story | 8 | script: Frank Tieri; pencils: John Paul Leon; inks: John Paul Leon; colors: Dave Stewart; letters: VC's Rus Wooton, VC's Joe Caramagna; editing: Tom Brevoort | Jack O'Lantern |
| 25 | Made Men: Gamma Corps | comic story | 8 | script: Frank Tieri; pencils: Ben Oliver; inks: Ben Oliver; colors: Edgar Delgado; letters: VC's Rus Wooton, VC's Joe Caramagna; editing: Tom Brevoort | Black Bolt, Blackagar Boltagon, Iron Man, Iron Patriot, Mister Fantastic, Norman Osborn, Reed Richards, Tony Stark, Doctor Strange, Stephen Strange |
| 26 | Made Men: Enforcer | comic story | 8 | script: Frank Tieri; pencils: Antonio Fuso; inks: Antonio Fuso; colors: Antonio Fabela; letters: VC's Rus Wooton, VC's Joe Caramagna; editing: Tom Brevoort | Bulldozer, Brian Calusky, Henry Camp, Charles Delazny Jr., Eliot Franklin, Dirk Garthwaite, The Hood, Piledriver, Parker Robbins, Thunderball, The Wrecker |
| 27 | Dark Reign: Zodiac Character Designs | illustration | 3 | pencils: Nathan Fox | |