| 0 | - | cover | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | Deadpool, Wade Wilson |
| 1 | - | credits, title page | 1 | pencils: Tony Moore; inks: Tony Moore; colors: Val Staples | Deadpool, Doctor Strange, Emily Preston, Stephen Strange, Wade Wilson, Wong |
| 2 | In Wade We Trust | cover reprint (on interior page) | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | |
| 3 | In Wade We Trust | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Joe Sabino | Captain America, Jimmy Carter, Gerald Ford, Abraham Lincoln, Richard Nixon, Thor Odinson, Franklin D. Roosevelt, Thor, Harry S. Truman, George Washington, Deadpool, Ulysses S. Grant, Andrew Jackson, John F. Kennedy |
| 4 | We Fought a Zoo | cover reprint (on interior page) | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | Deadpool, Wade Wilson |
| 5 | We Fought A Zoo | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Joe Sabino | Deadpool, Doctor Strange, Benjamin Franklin, John F. Kennedy, Theodore Roosevelt, Stephen Strange, George Washington, Wade Wilson, Wong, Agent Gorman, Michael Hawthorne First, Necromancer, Emily Preston |
| 6 | Dr. Strange Lives | cover reprint (on interior page) | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | |
| 7 | Dr. Strange Lives | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Joe Sabino | Deadpool, Doctor Strange, Gerald Ford, Benjamin Franklin, Abraham Lincoln, Richard Nixon, Stephen Strange, George Washington, Wade Wilson, Wong, Michael Hawthorne First, Necromancer |
| 8 | The Quick and the Dead and the Really Dead | cover reprint (on interior page) | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | Deadpool, Abraham Lincoln, Wade Wilson |
| 9 | The Quick and the Dead and the Really Dead | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Joe Sabino | John Adams, John Quincy Adams, Calvin Coolidge, Deadpool, Benjamin Franklin, Herbert Hoover, Andrew Jackson, John F. Kennedy, Abraham Lincoln, John Tyler, Martin Van Buren First, Wade Wilson, Emily Preston, Ronald Reagan |
| 10 | Star Wars: Revenge of the Gipper | cover reprint (on interior page) | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | Deadpool, Wade Wilson |
| 11 | Star Wars: Revenge of the Gipper | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Joe Sabino | Deadpool, Benjamin Franklin, Lyndon Johnson, George Washington, Wade Wilson, Emily Preston, Ronald Reagan, Michael Hawthorne First, Necromancer |
| 12 | - | cover reprint (on interior page) | 0.25 | pencils: Skottie Young; inks: Skottie Young | |
| 13 | - | cover reprint (on interior page) | 0.25 | pencils: Tony Moore; inks: Tony Moore; colors: Tony Moore | Deadpool, Wade Wilson |
| 14 | - | cover reprint (on interior page) | 0.25 | pencils: Tradd Moore; inks: Tradd Moore; colors: Marte Gracia | |
| 15 | - | cover reprint (on interior page) | 0.25 | pencils: Chris Bachalo; inks: Tim Townsend; colors: Chris Bachalo | Deadpool, Wade Wilson |
| 16 | National Maul | cover reprint (on interior page) | 1 | pencils: Zachary Baldus; inks: Zachary Baldus; colors: Zachary Baldus | Deadpool, George Washington, Wade Wilson |
| 17 | National Maul | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Clayton Cowles | Bruce Banner, Clint Barton, Black Widow, Captain America, Deadpool, Doctor Strange, Dwight D. Eisenhower, Ulysses S. Grant, William Henry Harrison First, Hawkeye, Hulk, Iron Man, Thomas Jefferson, Lyndon Johnson |
| 18 | - | cover reprint (on interior page) | 0.25 | pencils: Carlo Barberi; inks: Carlo Barberi; colors: Edgar Delgado | |
| 19 | - | cover reprint (on interior page) | 0.25 | pencils: Charles Paul Wilson III; inks: Charles Paul Wilson III | |
| 20 | - | cover reprint (on interior page) | 0.25 | pencils: Gurihiru; inks: Gurihiru | |
| 21 | - | cover reprint (on interior page) | 0.25 | pencils: Daniel Acuña; inks: Daniel Acuña; colors: Daniel Acuña | Deadpool, Doctor Strange, Stephen Strange, Wade Wilson |
| 22 | - | cover reprint (on interior page) | 0.25 | pencils: Tradd Moore; inks: Tradd Moore; colors: Marte Gracia | Deadpool, Abraham Lincoln, Wade Wilson |
| 23 | - | cover reprint (on interior page) | 0.25 | pencils: Giuseppe Camuncoli; inks: Giuseppe Camuncoli; colors: Marte Gracia | Deadpool, Wade Wilson |
| 24 | - | cover reprint (on interior page) | 0.25 | pencils: Adam Warren; inks: Adam Warren; colors: Guru eFX | Deadpool, George Washington, Wade Wilson |
| 25 | Dear Deadpool | letters page | 4 | script: ? [as Deadpool]; letters: typeset | |
| 26 | - | promo (ad from the publisher) | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | Deadpool, Abraham Lincoln, Wade Wilson |