| 0 | - | cover | 1 | pencils: Greg Land; inks: Greg Land; colors: Frank D'Armata | Domino, Neena Thurman |
| 1 | Title Page and Credits | credits, title page | 3 | pencils: David Baldeón; inks: David Baldeón; colors: Jesus Aburtov | |
| 2 | - | cover reprint (on interior page) | 1 | pencils: Greg Land; inks: Greg Land; colors: Frank D'Armata | Domino, Neena Thurman |
| 3 | Killer Instinct Part One Lottery | comic story | 20 | script: Gail Simone; pencils: David Baldeón; inks: David Baldeón; colors: Jesus Aburtov; letters: VC's Clayton Cowles | Alison Blaire, Cable, Amadeus Cho, Colossus, Dazzler, Deadpool, Diamondback, Domino, Gorilla-Man, Ken Hale, Hulk, Rachel Leighton, Logan, Tony Masters |
| 4 | - | cover reprint (on interior page) | 1 | pencils: Greg Land; inks: Greg Land; colors: Frank D'Armata | Domino, Neena Thurman |
| 5 | Killer Instinct Part Two Topaz | comic story | 20 | script: Gail Simone; pencils: David Baldeón; inks: David Baldeón; colors: Jesus Aburtov; letters: VC's Clayton Cowles | Alison Blaire, Cable, Amadeus Cho, Colossus, Dazzler, Deadpool, Diamondback, Domino, Gorilla-Man, Ken Hale, Hulk, Laura Kinney, Rachel Leighton, Tony Masters |
| 6 | - | cover reprint (on interior page) | 1 | pencils: Greg Land; inks: Greg Land; colors: Frank D'Armata | Diamondback, Domino, Rachel Leighton, Neena Thurman |
| 7 | Killer Instinct Part Three No Luck at All | comic story | 20 | script: Gail Simone; pencils: David Baldeón, Anthony Piper; inks: David Baldeón, Anthony Piper; colors: Jesus Aburtov; letters: VC's Clayton Cowles | Amadeus Cho, Diamondback, Domino, Hulk, Rachel Leighton, Shang-Chi, Neena Thurman |
| 8 | - | cover reprint (on interior page) | 1 | pencils: Greg Land; inks: Greg Land; colors: Frank D'Armata | Domino, Shang-Chi, Neena Thurman |
| 9 | Killer Instinct Part Four Like a Sword Made of Flesh | comic story | 20 | script: Gail Simone; pencils: David Baldeón; inks: David Baldeón; colors: Jesus Aburtov; letters: VC's Clayton Cowles | Deadpool, Diamondback, Domino, Rachel Leighton, Shang-Chi, Neena Thurman, Wade Wilson |
| 10 | #1 Variant | cover reprint (on interior page) | 1 | pencils: David Baldeón; inks: David Baldeón; colors: Jesus Aburtov | Domino, Neena Thurman |
| 11 | - | cover reprint (on interior page) | 1 | pencils: Greg Land; inks: Jay Leisten; colors: Frank D'Armata | Domino, Neena Thurman |
| 12 | Killer Instinct Part Five Onimod | comic story | 20 | script: Gail Simone; pencils: Michael Shelfer, David Baldeón; inks: Michael Shelfer; colors: Jesus Aburtov; letters: VC's Clayton Cowles | Diamondback, Domino, Rachel Leighton, Shang-Chi, Neena Thurman |
| 13 | - | cover reprint (on interior page) | 1 | pencils: Greg Land; inks: Greg Land; colors: Frank D'Armata | Domino, Neena Thurman |
| 14 | Killer Instinct Conclusion Sudden Death | comic story | 20 | script: Gail Simone; pencils: David Baldeón; inks: David Baldeón; colors: Jesus Aburtov; letters: VC's Clayton Cowles | Cable, Colossus, Diamondback, Domino, Rachel Leighton, Old Man Logan, Piotr Rasputin, Nathan Summers, Neena Thurman |
| 15 | Character Designs | illustration | 2 | script: Gail Simone, David Baldeón; pencils: David Baldeón; inks: David Baldeón; colors: David Baldeón | |
| 16 | #1 Variant | cover reprint (on interior page) | 1 | pencils: Elsa Charretier; inks: Elsa Charretier; colors: Matthew Wilson | Domino, Neena Thurman |
| 17 | #1 Variant | cover reprint (on interior page) | 1 | pencils: J. Scott Campbell; inks: J. Scott Campbell; colors: Sabine Rich | Cable, Colossus, Domino, Logan, James Proudstar, Piotr Rasputin, Nathan Summers, Neena Thurman, Warpath, Wolverine |
| 18 | #1 Action Figure Variant | cover reprint (on interior page) | 0.5 | pencils: John Tyler Christopher; inks: John Tyler Christopher; colors: John Tyler Christopher | Domino, Neena Thurman |
| 19 | #1 Variant | cover reprint (on interior page) | 0.5 | pencils: Rob Liefeld; inks: Rob Liefeld; colors: Leonardo Paciarotti | Cable, Deadpool, Domino, Nathan Summers, Neena Thurman, Wade Wilson |