| 0 | - | cover | 1 | pencils: Ryan Stegman; inks: Ryan Stegman; colors: Paul Mounts | Fantastic Four [Mr. Fantastic [Reed Richards]; Invisible Woman [Sue Storm Richards]; Human Torch [Johnny Storm]; Thing [Ben Grimm]] |
| 1 | End of Line | comic story | 20 | script: Jonathan Hickman; pencils: Ron Garney; inks: Ron Garney; colors: Jason Keith; letters: Clayton Cowles | Nathaniel Richards; Reed Richards; The Thing; Bentley |
| 2 | Origin Story | comic story | 20 | script: Jonathan Hickman; pencils: Mike Choi; inks: Mike Choi; colors: Cris Peter; letters: VC's Clayton Cowles | Council of Reed Richardses; Reed Richards (unknown universe); Susan Sturm (unknown universe, death); Johnny Sturm (unknown universe, death); Benjamin Grimm (unknown universe, death); Viktor Von Doom (unknown universe, death); Adolf Hitler (unknown universe, death); Avengers (unknown universe, death) |
| 3 | Adventures in Red | comic story | 20 | script: Jonathan Hickman; pencils: Ron Garney; inks: Ron Garney; colors: Jason Keith; letters: Clayton Cowles | Ben Grimm, Human Torch, Invisible Woman, Willie Lumpkin, Mister Fantastic, Franklin Richards, Reed Richards, Susan Storm Richards, Valeria Richards, Johnny Storm, The Thing |
| 4 | The Roommate Experiment | comic story | 20 | script: Jonathan Hickman; pencils: Nick Dragotta; inks: Nick Dragotta; colors: Chris Sotomayor; letters: Clayton Cowles | Spider-Man; Human Torch; Max Modell; Bella Fishbach; Grady Scraps; Light Brigade [Dara Ko Oke; Voorr; Els Udonta; Hooud; Kal Blackbane; Prax Ord]; Mik; Mary Jane Watson; Annihilus |
| 5 | What Do You Call the Opposite of a Field Trip? | comic story | 20 | script: Jonathan Hickman; pencils: Nick Dragotta; inks: Nick Dragotta; colors: Chris Sotomayor; letters: Clayton Cowles | Bentley, Black Bolt, Blackagar Boltagon, Medusalith Amaquelin Boltagon, Dragon Man, Jim Hammond, Human Torch, The Supreme Intelligence, Invisible Woman, Leech, Artie Maddicks, Medusa, Mister Fantastic, Onomi Whitemane |
| 6 | Inert | comic story | 20 | script: Jonathan Hickman; pencils: Giuseppe Camuncoli; inks: Karl Kesel; colors: Paul Mounts; letters: Clayton Cowles | Black Panther; Storm; Future Foundation [Mister Fantastic; Invisible Woman; Franklin Richards; Valeria Richards; Alex Power; Bentley 23; Wu; Vil; Artie Maddicks; Mik; Korr; Dragon Man]; Amon-Ra; Anubis; Bastet; Shuri; Dora Milaje |
| 7 | City of the Dead | comic story | 20 | script: Jonathan Hickman; pencils: Giuseppe Camuncoli; inks: Karl Kesel; colors: Paul Mounts; letters: Clayton Cowles | Fantastic Four [Mr. Fantastic; Invisible Woman]; Black Panther; Shuri; Storm [Ororo Munroe]; Anubis; Panther God [Bastet] |
| 8 | Safari | comic story | 20 | script: Jonathan Hickman; pencils: Gabriel Hernández Walta; inks: Gabriel Hernández Walta; colors: Cris Peter; letters: Clayton Cowles | Bentley, Dragon Man, Leech, Artie Maddicks, Alex Power, Franklin Richards, Valeria Richards, Shuri, Vil, Wu |
| 9 | Deus Ex Inhuman | comic story | 20 | script: Jonathan Hickman; pencils: Nick Dragotta; inks: Nick Dragotta; colors: Chris Sotomayor; letters: VC's Clayton Cowles | Supreme Intelligence; Kree; Inhumans [Karnak; Black Bolt; Medusa; Lockjaw]; Light Brigade [Els Udonta; Dara Ko Oke; Hooud; Kal Blackbane; Voorr; Prax Ord]; Annihilus; Future Foundation [Human Torch; Reed Richards; Bentley 23; Dragon Man; Franklin Richards; Korr; Leech; Mik; Valeria Richards; Wu; Vil |
| 10 | Ronance | comic story | 20 | script: Jonathan Hickman; pencils: Nick Dragotta; inks: Nick Dragotta; colors: Cris Peter; letters: Clayton Cowles | Onome; Valeria Richards; Dragon Man; Alex Power; Tong; Mik; Korr; Turg; Wu; Vil; Leech; Artie Maddocks; Bentley; Reed Richards; future Franklin Richards; Black Bolt; Supreme Intelligence; Kree; Medusa; Sue Storm Richards; Johhny Storm; Spider-Man; Lockjaw; Inhumans; Light Brigade [Kal Blackbane; Pra |
| 11 | The God Ship | comic story | 20 | script: Jonathan Hickman; pencils: Ryan Stegman; inks: Ryan Stegman; colors: Paul Mounts; letters: Clayton Cowles | Alyssa Moy; Future Foundation [Human Torch; Invisible Woman; Mr. Fantastic; Thing; Spider-Man]; Ted Castle; Defenders of Nu-World [Banner Jr; Lightwave; Hooded Man; Alex Ultron; Natalie X; Psionics] |
| 12 | The Wizard | comic story | 20 | script: Jonathan Hickman; pencils: Ryan Stegman; inks: Ryan Stegman; colors: Paul Mounts; letters: Clayton Cowles | A.I.M.; President Obama; Captain America; Mister Fantastic; Hank Pym; Iron Man [Tony Stark]; Invisible Woman; The Thing; Human Torch; Spider-Man; The Wizard; Andrew Forson; Bentley |
| 13 | You Are Whatever You Want To Be | comic story | 20 | script: Jonathan Hickman; pencils: André Araújo; inks: André Araújo; colors: Cris Peter; letters: Clayton Cowles | Bentley, Dragon Man, Ben Grimm, Human Torch, Invisible Woman, Mister Fantastic, Peter Parker, Alex Power, Reed Richards, Susan Storm Richards, Valeria Richards, Spider-Man, Johnny Storm, The Thing |
| 14 | Foundation | comic story | 22 | script: Jonathan Hickman; pencils: Ryan Stegman; inks: Ryan Stegman; colors: Paul Mounts; letters: Clayton Cowles | Dr. Doom [Victor von Doom]; Valeria Richards (flashback); older Valeria Richards; Mr. Fantastic [Reed Richards]; Nathaniel Richards |
| 15 | Run | comic story | 22 | script: Jonathan Hickman; pencils: Nick Dragotta; inks: Nick Dragotta; colors: Cris Peter; letters: Clayton Cowles | Bentley, Dragon Man, Invisible Woman, Leech, Mister Fantastic, Alex Power, Franklin Richards, Franklin Richards, Reed Richards, Susan Storm Richards, Valeria Richards, Valeria Richards, Vil, Wu |
| 16 | - | cover reprint (on interior page) | 1 | pencils: Ron Garney; inks: Ron Garney; colors: Jason Keith | |
| 17 | Origin Story | comic story | 20 | script: Jonathan Hickman; pencils: Mike Choi; inks: Mike Choi; colors: Cris Peter; letters: VC's Clayton Cowles | Council of Reed Richardses; Reed Richards (unknown universe); Susan Sturm (unknown universe, death); Johnny Sturm (unknown universe, death); Benjamin Grimm (unknown universe, death); Viktor Von Doom (unknown universe, death); Adolf Hitler (unknown universe, death); Avengers (unknown universe, death) |
| 18 | - | cover reprint (on interior page) | 1 | pencils: Mike Choi; inks: Mike Choi; colors: Guru eFX | Ben Grimm, Human Torch, Invisible Woman, Mister Fantastic, Reed Richards, Susan Storm Richards, Johnny Storm, The Thing |
| 19 | - | cover reprint (on interior page) | 1 | pencils: Mike Choi; inks: Mike Choi; colors: Guru eFX | Black Panther |
| 20 | - | cover reprint (on interior page) | 1 | pencils: Frank Cho; inks: Frank Cho; colors: Jason Keith | Black Panther, Invisible Woman, Ororo Munroe, Susan Storm Richards, Storm, T'Challa |
| 21 | - | cover reprint (on interior page) | 1 | pencils: Ryan Stegman; colors: Paul Mounts; letters: Ryan Stegman | |
| 22 | - | cover reprint (on interior page) | 1 | pencils: Mike Choi; inks: Mike Choi; colors: Guru eFX | Human Torch, Peter Parker, Spider-Man, Johnny Storm |
| 23 | - | cover reprint (on interior page) | 1 | pencils: Kalman Andrasofszky; inks: Kalman Andrasofszky; colors: Kalman Andrasofszky | |
| 24 | - | cover reprint (on interior page) | 1 | pencils: Mike Choi; inks: Mike Choi; colors: Guru eFX | Franklin Richards, Valeria Richards |
| 25 | - | cover reprint (on interior page) | 1 | pencils: Mike Choi; inks: Mike Choi; colors: Guru eFX | All-Knowing, Kal Blackbane, Creeping Death, Dara Ko Eke, Hooud, Metallic Titan, Midnight Blade, Prax Ord, Franklin Richards, Valeria Richards, Stonethrower, Els Udonta |
| 26 | - | cover reprint (on interior page) | 1 | pencils: Mike Choi; inks: Mike Choi; colors: Guru eFX | |
| 27 | - | cover reprint (on interior page) | 1 | pencils: Ryan Stegman; inks: Ryan Stegman; colors: Paul Mounts | Ben Grimm, Human Torch, Invisible Woman, Mister Fantastic, Reed Richards, Susan Storm Richards, Johnny Storm, The Thing, Bentley Wittman, Wizard |
| 28 | - | cover reprint (on interior page) | 1 | pencils: Ryan Stegman; inks: Ryan Stegman; colors: Marte Gracia | |
| 29 | - | cover reprint (on interior page) | 1 | pencils: Ryan Stegman; inks: Ryan Stegman; colors: Paul Mounts | Ben Grimm, Human Torch, Invisible Woman, Mister Fantastic, Reed Richards, Susan Storm Richards, Johnny Storm, The Thing |
| 30 | - | cover reprint (on interior page) | 1 | pencils: Ryan Stegman; inks: Ryan Stegman; colors: Chris Sotomayor | |
| 31 | - | cover reprint (on interior page) | 1 | pencils: Kalman Andrasofszky; inks: Kalman Andrasofszky; colors: Kalman Andrasofszky | |
| 32 | - | cover reprint (on interior page) | 1 | pencils: Billy Tan; inks: Billy Tan; colors: Edgar Delgado | |
| 33 | 50 years of Fantastic Four Variant Edition | cover reprint (on interior page) | 1 | pencils: Siobhan Hanna; inks: Siobhan Hanna; colors: Siobhan Hanna | Fantastic Four [Mr. Fantastic [Reed Richards]; The Thing [Ben Grimm]; Human Torch [Johnny Storm]; Medusa [Medusalith Amaquelin]] |
| 34 | - | cover reprint (on interior page) | 1 | pencils: Joe Quinones; inks: Joe Quinones; colors: Joe Quinones | Fantastic Four [Mr. Fantastic [Reed Richards]; Invisible Woman [Sue Richards Storm]; She-Hulk [Jennifer Walters]; Human Torch [Johnny Storm]] |
| 35 | - | cover reprint (on interior page) | 1 | pencils: Marko Djurdjević; inks: Marko Djurdjević; colors: Marko Djurdjević | Fantastic Four [Mr. Fantastic [Reed Richards]; Invisible Woman [Sue Richards Storm]; Thing [Ben Grimm]; Spider-Man [Peter Parker]] |
| 36 | - | cover reprint (on interior page) | 1 | pencils: Marko Djurdjević; inks: Marko Djurdjević; colors: Marko Djurdjević | Ant-Man, Luke Cage, Crystal, Scott Lang, Crystalia Amaquelin Maximoff, Power Man, She-Thing, Sharon Ventura |
| 37 | - | cover reprint (on interior page) | 1 | pencils: Paolo Rivera; inks: Paolo Rivera; colors: Paolo Rivera | Black Bolt, Blackagar Boltagon, Galactus, Galan, Norrin Radd, Silver Surfer, Uatu, The Watcher |
| 38 | - | illustration | 1 | pencils: Gabriel Hernández Walta; inks: Gabriel Hernández Walta | |
| 39 | - | illustration | 1 | pencils: André Lima Araújo; inks: André Lima Araújo | |
| 40 | - | illustration | 1 | pencils: Ryan Stegman; inks: Ryan Stegman | |