| 0 | - | cover | 1 | pencils: Amy Reeder; inks: Amy Reeder; colors: Amy Reeder | Lunella Lafayette [Moon Girl] |
| 1 | Title Page and Credits | credits, title page | 3 | pencils: Natacha Bustos; inks: Natacha Bustos; colors: Tamra Bonvillain | |
| 2 | - | cover reprint (on interior page) | 1 | pencils: Amy Reeder; inks: Amy Reeder; colors: Amy Reeder | Lunella Lafayette [Moon Girl] |
| 3 | The Smartest There Is! Part One: Marvel Now or Never! | comic story | 20 | script: Brandon Montclare, Amy Reeder; pencils: Natacha Bustos; inks: Natacha Bustos; colors: Tamra Bonvillain; letters: Travis Lanham | Moon Girl [Lunella Lafayette]; Devil Dinosaur; Hulk [Amadeus Cho]; Mole Man; Moloids; Thing [Benjamin J. Grimm] |
| 4 | - | cover reprint (on interior page) | 1 | pencils: Natacha Bustos; inks: Natacha Bustos; colors: Natacha Bustos | Moon Girl [Lunella Lafayette]; Devil Dinosaur; Ms. Marvel [Kamala Khan] |
| 5 | - | cover reprint (on interior page) | 1 | pencils: Amy Reeder; inks: Amy Reeder; colors: Amy Reeder | Moon Girl [Lunella Lafayette]; Devil Dinosaur; Hulk [Amadeus Cho]; Thing [Benjamin J. Grimm] |
| 6 | The Smartest There Is! Part Two: Yancy Street Smarts | comic story | 20 | script: Brandon Montclare, Amy Reeder; pencils: Ray-Anthony Height; inks: Ray-Anthony Height; colors: Tamra Bonvillain; letters: Travis Lanham | Moon Girl [Lunella Lafayette]; Thing [Benjamin J. Grimm]; Hulk [Amadeus Cho]; Doombot |
| 7 | - | cover reprint (on interior page) | 1 | pencils: Amy Reeder; inks: Amy Reeder; colors: Amy Reeder | Ironheart [Riri Williams]; Moon Girl [Lunella Lafayette]; Devil Dinosaur |
| 8 | The Smartest There Is! Part Three: Code | comic story | 20 | script: Brandon Montclare, Amy Reeder; pencils: Natacha Bustos; inks: Natacha Bustos; colors: Tamra Bonvillain; letters: Travis Lanham | Moon Girl [Lunella Lafayette]; Ironheart [Riri Williams]; Doombot; Devil Dinosaur; Doctor Strange [Stephen Strange] |
| 9 | - | cover reprint (on interior page) | 1 | pencils: Amy Reeder; inks: Amy Reeder; colors: Amy Reeder | Moon Girl [Lunella Lafayette]; Devil Dinosaur; Doctor Strange |
| 10 | The Smartest There Is! Part Four: Science Fiction | comic story | 20 | script: Brandon Montclare, Amy Reeder; pencils: Natacha Bustos; inks: Natacha Bustos; colors: Tamra Bonvillain; letters: Travis Lanham | Moon Girl [Lunella Lafayette]; Devil Dinosaur; Doctor Strange [Stephen Strange]; Doombot; X-Men [Forge; Storm [Ororo Munroe]; Wolverine [Logan]; Colossus [Peter Rasputin]; Nightcrawler [Kurt Wagner]] |
| 11 | - | cover reprint (on interior page) | 1 | pencils: Amy Reeder; inks: Amy Reeder; colors: Amy Reeder | Moon Girl [Lunella Lafayette]; X-Men [Wolverine [Logan]; Storm [Ororo Munroe]; Colossus [Peter Rasputin]; Nightcrawler [Kurt Wagner]; Forge]; Devil Dinosaur |
| 12 | The Smartest There Is! Part Five: X Equals | comic story | 20 | script: Brandon Montclare, Amy Reeder; pencils: Natacha Bustos; inks: Natacha Bustos; colors: Tamra Bonvillain; letters: Travis Lanham | Moon Girl [Lunella Lafayette]; X-Men [Nightcrawler [Kurt Wagner]; Colossus [Peter Rasputin]; Storm [Ororo Munroe]; Wolverine [Logan]; Forge]; Devil Dinosaur; Doombot |
| 13 | - | cover reprint (on interior page) | 1 | pencils: Amy Reeder; inks: Amy Reeder; colors: Amy Reeder | Moon Girl [Lunella Lafayette]; Devil Dinosaur; Doombot |
| 14 | The Smartest There Is! Part Six: Full Moon | comic story | 20 | script: Brandon Montclare, Amy Reeder; pencils: Natacha Bustos; inks: Natacha Bustos; colors: Tamra Bonvillain; letters: Travis Lanham | Moon Girl [Lunella Lafayette]; Killer-Folk; Thing [Benjamin J. Grimm]; Doombot; Devil Dinosaur; Hulk [Amadeus Cho]; Ms. Marvel [Kamala Khan]; Doctor Strange [Stephen Strange]; Ironheart [Riri Williams]; X-Men [Wolverine [Logan]; Colossus [Peter Rasputin]; Storm [Ororo Munroe]; Nightcrawler [Kurt Wag |
| 15 | - | cover reprint (on interior page) | 1 | pencils: Sanford Greene; inks: Sanford Greene; colors: Sanford Greene | Moon Girl [Lunella Lafayette]; Devil Dinosaur |
| 16 | - | cover reprint (on interior page) | 1 | pencils: Joyce Chin; inks: Joyce Chin; colors: Chris Sotomayor | Moon Girl [Lunella Lafayette]; Devil Dinosaur |
| 17 | - | cover reprint (on interior page) | 1 | pencils: Pascual Ferry; inks: Pascual Ferry; colors: Frank D'Armata | Moon Girl [Lunella Lafayette]; Devil Dinosaur |
| 18 | - | cover reprint (on interior page) | 1 | pencils: Larry Stroman; inks: John Dell; colors: Dave McCaig | Moon Girl [Lunella Lafayette]; Devil Dinosaur |
| 19 | That's Right, the Rumors Are True: Lunella Lafayette Is the Smartest There Is! | promo (ad from the publisher) | 1 | pencils: Amy Reeder; inks: Amy Reeder; colors: Amy Reeder | Moon Girl [Lunella Lafayette]; Devil Dinosaur |