| 0 | - | cover | 1 | pencils: David Finch; inks: David Finch; colors: Frank D'Armata | Peter Parker, Spider-Man |
| 1 | - | cover reprint (on interior page) | 1 | pencils: David Finch; inks: David Finch; colors: Frank D'Armata | Peter Parker, Spider-Man |
| 2 | Big Brain Day Chapter One | comic story | 20 | script: Joe Kelly; pencils: Chris Bachalo; inks: Tim Townsend; colors: Marcio Menyz; letters: VC's Travis Lanham | Baron Zemo, Peter Parker, Spider-Man, Helmut Zemo |
| 3 | #1 Variant | cover reprint (on interior page) | 1 | pencils: Chris Bachalo; inks: Tim Townsend; colors: Chris Bachalo | Peter Parker, Spider-Man |
| 4 | - | cover reprint (on interior page) | 1 | pencils: David Finch; inks: David Finch; colors: Frank D'Armata | Peter Parker, Spider-Man |
| 5 | Big Brain Day Chapter Two | comic story | 20 | script: Joe Kelly; pencils: Chris Bachalo; inks: Tim Townsend, Al Vey, Wayne Faucher; colors: Marcio Menyz; letters: VC's Travis Lanham | Baron Zemo, Peter Parker, Spider-Man, Helmut Zemo |
| 6 | #2 Variant | cover reprint (on interior page) | 1 | pencils: Chris Bachalo; inks: Tim Townsend; colors: Chris Bachalo | Peter Parker, Spider-Man |
| 7 | - | cover reprint (on interior page) | 1 | pencils: David Finch; inks: David Finch; colors: Frank D'Armata | Peter Parker, Spider-Man |
| 8 | Big Brain Play Chapter Three | comic story | 22 | script: Joe Kelly; pencils: Chris Bachalo; inks: Tim Townsend, Al Vey, Wayne Faucher, John Livesay, Jaime Mendoza; colors: Marcio Menyz; letters: VC's Travis Lanham | Baron Zemo, Peter Parker, Spider-Man, Helmut Zemo |
| 9 | - | cover reprint (on interior page) | 1 | pencils: David Finch; inks: David Finch; colors: Frank D'Armata | Baron Zemo, Peter Parker, Spider-Man, Helmut Zemo |
| 10 | The Secret Lives of Savages Chapter One | comic story | 22 | script: Joe Kelly; pencils: Chris Bachalo; inks: Tim Townsend, Al Vey, Wayne Faucher, John Livesay, Jaime Mendoza; colors: Marcio Menyz, Erick Arciniega; letters: VC's Travis Lanham | Baron Zemo, Peter Parker, Spider-Man, Helmut Zemo |
| 11 | - | cover reprint (on interior page) | 1 | pencils: R. B. Silva; inks: R. B. Silva; colors: Edgar Delgado | Peter Parker, Spider-Man |
| 12 | The Secret Lives of Savages Chapter Two | comic story | 20 | script: Joe Kelly; pencils: Chris Bachalo, Cory Smith, Gerardo Sandoval; inks: Tim Townsend, Wayne Faucher, Cory Smith, Víctor Nava, Victor Olazaba, Gerardo Sandoval; colors: Jim Charalampidis, Chris Sotomayor; letters: VC's Travis Lanham | Baron Zemo, Peter Parker, Spider-Man, Helmut Zemo |
| 13 | #1 Party Variant | cover reprint (on interior page) | 1 | pencils: Todd Nauck; inks: Todd Nauck; colors: Rachelle Rosenberg | Peter Parker, Spider-Man |
| 14 | #1 Wraparound Variant | cover reprint (on interior page) | 2 | pencils: Chris Bachalo; inks: Tim Townsend; colors: Chris Bachalo | Baron Zemo, Eddie Brock, Curt Connors, Doctor Octopus, Lizard, Otto Octavius, Peter Parker, Rhino, Spider-Man, Aleksei Sytsevich, Adrian Toomes, Venom, The Vulture, Helmut Zemo |
| 15 | #1 Variant | cover reprint (on interior page) | 1 | pencils: Adam Kubert; inks: Adam Kubert; colors: Richard Isanove | Peter Parker, Spider-Man |
| 16 | #1 Variant | cover reprint (on interior page) | 1 | pencils: Ken Lashley; inks: Ken Lashley; colors: Juan Fernandez | Peter Parker, Spider-Man |
| 17 | #1 Variant | cover reprint (on interior page) | 1 | pencils: Skottie Young; inks: Skottie Young; colors: Jean-Francois Beaulieu | |
| 18 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: Greg LaRocque; inks: Greg LaRocque; colors: Chris Sotomayor | Black Cat, Frank Castle, Doctor Octopus, Felicia Hardy, Flint Marko, Otto Octavius, Peter Parker, Punisher, Sandman, Spider-Man, Adrian Toomes, The Vulture |
| 19 | #1 Hidden Gem Variant | cover reprint (on interior page) | 0.25 | pencils: Larry Lieber; inks: Frank Giacoia; colors: Chris Sotomayor | J. Jonah Jameson, Peter Parker, Robbie Robertson, Spider-Man |
| 20 | #2 Variant | cover reprint (on interior page) | 0.5 | pencils: Takashi Okazaki; inks: Takashi Okazaki; colors: Rico Renzi | Peter Parker, Spider-Man |
| 21 | #3 Variant | cover reprint (on interior page) | 1 | pencils: Chris Bachalo; inks: Tim Townsend; colors: Chris Bachalo | Peter Parker, Spider-Man |
| 22 | #4 Variant | cover reprint (on interior page) | 1 | pencils: Peach Momoko; inks: Peach Momoko; colors: Peach Momoko | Peter Parker, Spider-Man |
| 23 | #5 Variant | cover reprint (on interior page) | 1 | pencils: Kael Ngu; inks: Kael Ngu; colors: Kael Ngu | Peter Parker, Spider-Man |