| 0 | - | cover | 1 | pencils: Tom Grummett; inks: Tom Grummett; colors: Morry Hollowell | Annihilus, Black Bolt, Blackagar Boltagon, Doctor Doom, Victor Von Doom, Harvey Elder, Galactus, Galan, Ben Grimm, Human Torch, Invisible Woman, Mister Fantastic, Mole Man, Psycho-Man |
| 1 | Credits and Indicia | credits, title page | 1 | letters: typeset | |
| 2 | Annihilus | character profile | 2 | script: Anthony Flamini; pencils: Joe Bennett; inks: Sandu Florea; colors: Liquid!, Digital Chameleon | Annihilus |
| 3 | Doctor Doom | character profile | 4 | script: Michael Hoskin; pencils: Dale Keown, Mike Wieringo; inks: Karl Kesel; colors: Richard Isanove | Doctor Doom, Victor Von Doom |
| 4 | Fantastic Four | character profile | 3 | script: Sean McQuaid; pencils: Mike McKone, John Byrne; inks: Mike McKone, John Byrne; colors: Paul Mounts | Ben Grimm, Human Torch, Invisible Woman, Mister Fantastic, Franklin Richards, Reed Richards, Susan Storm Richards, Johnny Storm, The Thing |
| 5 | Galactus | character profile | 4 | script: Jeff Christiansen; pencils: Mike Wieringo; inks: Karl Kesel; colors: Paul Mounts | Galactus, Galan |
| 6 | Human Torch | character profile | 3 | script: Bill Lentz; pencils: Carlos Pacheco, Mike Wieringo; inks: Jesús Merino, Karl Kesel; colors: Liquid!, Paul Mounts | Human Torch, Johnny Storm |
| 7 | Inhumans | character profile | 3 | script: Michael Hoskin; pencils: Jae Lee, Adi Granov; inks: Jae Lee, Adi Granov; colors: Adi Granov | Alaris, Black Bolt, Blackagar Boltagon, Medusalith Amaquelin Boltagon, Crystal, Gorgon, Jolen, Karnak, Crystalia Amaquelin Maximoff, Medusa, Nahrees, San, Tonaja, Triton |
| 8 | Invisible Woman | character profile | 3 | script: Sean McQuaid; pencils: Tony Harris, Steve McNiven; inks: Tom Feister, Mark Morales; colors: Morry Hollowell | Invisible Woman, Susan Storm Richards |
| 9 | Mister Fantastic | character profile | 3 | script: Sean McQuaid; pencils: Mike Wieringo, Jim Muniz; inks: Karl Kesel, Cam Smith; colors: Paul Mounts, Brian Reber | Mister Fantastic, Reed Richards |
| 10 | Mole Man | character profile | 2 | script: Ronald Byrd; pencils: Mike Deodato Jr. | Harvey Elder, Mole Man |
| 11 | Alyssa Moy | character profile | 1 | script: Bill Lentz; pencils: Salvador Larroca; inks: Art Thibert | Alyssa Moy |
| 12 | Psycho-Man | character profile | 2 | script: Jeff Christiansen; pencils: John Byrne; inks: Joe Rubinstein | Psycho-Man |
| 13 | Ramades | character profile | 1 | script: Anthony Flamini; pencils: Jim Muniz; inks: Jim Royal; colors: Brian Reber | Ramades |
| 14 | Franklin Richards | character profile | 3 | script: Mark O'English; pencils: Terry Dodson, Jim Muniz; inks: Jim Royal, Derek Fridolfs; colors: Brian Reber | Franklin Richards, H.E.R.B.I.E. |
| 15 | Valeria Richards | character profile | 2 | script: Stuart Vandal; pencils: Mike Wieringo, Salvador Larroca; inks: Karl Kesel, Art Thibert | Valeria Richards, Marvel Girl |
| 16 | Silver Surfer | character profile | 3 | script: Sean McQuaid; pencils: Sean Chen, Lan Medina; inks: Avalon Studios; colors: Edgar Tadeo | Norrin Radd, Silver Surfer |
| 17 | Skrulls | character profile | 3 | script: Ronald Byrd; pencils: Carlos Pacheco, Jack Kirby, Scott Kolins; inks: Jesús Merino, Jack Kirby, Andy Lanning; colors: Liquid!, David Self | Kl'rt, Paibok, Super-Skrull, Dorrek |
| 18 | Thing | character profile | 3 | script: Sean McQuaid; pencils: Mike Wieringo; inks: Karl Kesel; colors: Paul Mounts | Ben Grimm, The Thing |
| 19 | Uatu the Watcher | character profile | 2 | script: Anthony Flamini; pencils: John Byrne; inks: Joe Rubinstein | Uatu, The Watcher |
| 20 | Bibliography | text article | 2 | script: Jeff Christiansen, Sean McQuaid, Anthony Flamini, Michael Hoskin, Bill Lentz, Ronald Byrd | |
| 21 | A Comprehensive Guide to the Fantastic Four | promo (ad from the publisher) | 1 | letters: typeset | |