| 0 | Omega the Unknown | cover | 1 | pencils: Gil Kane; inks: Frank Giacoia; colors: Tom Smith | |
| 1 | - | promo (ad from the publisher) | 1 | pencils: various; inks: various; colors: various; letters: typeset | |
| 2 | Omega the Unknown | credits, title page | 1 | inks: Jim Mooney, Pablo Marcos; colors: Jerron Quality Color | |
| 3 | - | cover reprint (on interior page) | 1 | pencils: Ed Hannigan; inks: Joe Sinnott; colors: Jerron Quality Color; letters: Danny Crespi | Omega the Unknown; James Michael Starling |
| 4 | Omega the Unknown | comic story | 18 | script: Mary Skrenes, Steve Gerber; pencils: Jim Mooney; inks: Jim Mooney; colors: Petra Goldberg; letters: John Costanza; editing: Marv Wolfman | |
| 5 | - | cover reprint (on interior page) | 1 | pencils: Rich Buckler; inks: Al Milgrom; letters: Danny Crespi | Omega; Hulk [Bruce Banner] |
| 6 | Welcome to Hell's Kitchen! | comic story | 17 | script: Steve Gerber, Mary Skrenes; pencils: Jim Mooney; inks: Jim Mooney; colors: Phil Rachelson; letters: Gaspar Saladino, Irving Watanabe | Hulk (within DEFENDERS #35); Gramps (Introduction); Electro, a Living Robot (Villain) |
| 7 | - | cover reprint (on interior page) | 1 | pencils: Gil Kane; inks: Frank Giacoia; letters: Irv Watanabe | Omega the Unknown; Elektro |
| 8 | Burn While You Learn! | comic story | 17 | script: Mary Skrenes, Steve Gerber; pencils: Jim Mooney; inks: Jim Mooney; colors: Hugh Paley; letters: Irving Watanabe | Principal Anderson (Introduction); Mr. Beal; Dian; John Nedley; Nick Delbello; Freddie; Electro (Villain); the Living Robot (Villain) |
| 9 | Night of a Thousand Claws! | cover reprint (on interior page) | 1 | pencils: Ed Hannigan; inks: Frank Giacoia; letters: Danny Crespi | Omega; El Gato |
| 10 | Cats and No Dogs! | comic story | 17 | script: Mary Skrenes, Steve Gerber; pencils: Jim Mooney; inks: Pablo Marcos; colors: Phil Rache; letters: Gaspar Saladino, Ray Holloway, Karen Mantlo | Omega; El Gato (villain, introduction); Teresa Mendez (introduction); Amber; James-Michael Starling; Dian; Gramps; Mark Antony (a cat); Nick Delbello; Mr. Lucien; John Nedley; Mr. Anderson |
| 11 | - | cover reprint (on interior page) | 1 | pencils: Gil Kane; inks: Frank Giacoia | Omega |
| 12 | Through the Rat Hole--Into the Cat's Lair! | comic story | 17 | script: Steve Gerber, Mary Skrenes; pencils: Jim Mooney; inks: Jim Mooney; colors: Janice Cohen; letters: Joe Rosen | Omega; Peter Parker [Spider-Man]; J. Jonah Jameson; El Gato (villain) |
| 13 | - | cover reprint (on interior page) | 1 | pencils: John Romita; inks: Dave Cockrum; colors: Tom Palmer; letters: Danny Crespi | |
| 14 | A Tug of the Wrench! | comic story | 17 | script: Mary Skrenes, Steve Gerber; pencils: Jim Mooney, Mike Esposito; inks: Mike Esposito; colors: Hugh Paley; letters: Joe Rosen | The Wrench [Kurt Klemmer] (villain, introduction); Mamie (introduction, death) |
| 15 | - | cover reprint (on interior page) | 1 | pencils: Dave Cockrum; inks: Dave Cockrum; letters: Danny Crespi | |
| 16 | Blockbuster! | comic story | 17 | script: Scott Edelman; pencils: Jim Mooney; inks: Jim Mooney; colors: Hugh Paley; letters: Joe Rosen | Blockbuster (formerly Man-Brute from CAPTAIN AMERICA #121, villain) |
| 17 | - | cover reprint (on interior page) | 1 | pencils: Gil Kane; inks: Frank Giacoia; letters: John Costanza | |
| 18 | A Blast from the Past | comic story | 17 | script: Roger Stern; pencils: Lee Elias; inks: Jim Mooney; colors: Janice Cohen; letters: Joe Rosen | Omega; Richard Rory; Nitro (villain); Foolkiller [Greg Salinger] (introduction) |
| 19 | Riot at Rockefeller Center! | cover reprint (on interior page) | 1 | pencils: Gil Kane; inks: Mike Esposito; letters: Irv Watanabe | |
| 20 | Fightin' Fools! | comic story | 17 | script: Steve Gerber, Mary Skrenes; pencils: Jim Mooney; inks: Jim Mooney; colors: Janice Cohen; letters: Gaspar Saladino, Susan Fox | Blockbuster (villain, death); Foolkiller II (villain) |
| 21 | - | cover reprint (on interior page) | 1 | pencils: Dave Cockrum; inks: Pablo Marcos; letters: Irv Watanabe | |
| 22 | The Hottest Slot in Town! | comic story | 17 | script: Steve Gerber, Mary Skrenes; pencils: Jim Mooney; inks: Jim Mooney; colors: Phil Rachelson; letters: Gaspar Saladino, Howard Bender | John Nedley (Death); Ruby Thursday; Dybbuk (Introduction); Omega (Death) |
| 23 | Defenders #75, Page 18 | comic story | 1 | script: Ed Hannigan; pencils: Herb Trimpe; inks: Mike Esposito; colors: Carl Gafford; letters: Irving Watanabe | Defenders [Valkyrie; Hellcat [Patsy Walker]]; Richard Rory; Amber Grant; Ledge; Lunatik (Flashback; Cameo); Milton Rosenblum; Fia Lundstrom (Reporter); Omega the Unknown (cameo, corpse) |
| 24 | At Last... The Omega Saga! | cover reprint (on interior page) | 1 | pencils: Rich Buckler; inks: Al Milgrom; colors: George Roussos; letters: Irv Watanabe | Bruce Banner, Brunnhilde, Hellcat, Hulk, Thursday Rubinstein, Ruby Thursday, Valkyrie, Patsy Walker |
| 25 | Little Triggers! | comic story | 17 | script: Steven Grant; pencils: Herb Trimpe; inks: Steve Mitchell; colors: George Roussos; letters: Gaspar Saladino, Clem Robins | Defenders [Hulk [Bruce Banner]; Valkyrie; Hellcat [Patsy Walker]; Nighthawk [Kyle Richmond]]; Omega the Unknown; Dibbuk; Ruby Thursday [Thursday Rubinstein]; Wasp [Janet van Dyne]; James-Michael Starling; Ruth; John (Flashback, Cameo); Dian; Richard Rory; Moondragon [Heather Douglas] |
| 26 | Waiting for the End of the World! | cover reprint (on interior page) | 1 | pencils: Rich Buckler; inks: Al Milgrom; colors: George Roussos; letters: Irv Watanabe | Bruce Banner, Brunnhilde, Heather Douglas, Hellcat, Hulk, Moondragon, Valkyrie, Janet Van Dyne, Patsy Walker, Wasp |
| 27 | Waiting for the End of the World! | comic story | 18 | script: Steven Grant, Mark Gruenwald; pencils: Herb Trimpe; inks: Al Milgrom, Chic Stone, Steve Mitchell; colors: George Roussos; letters: Joe Rosen | Defenders [Hulk [Bruce Banner]; Valkyrie; Red Guardian [Tania Belinsky] (cameo); Dr. Strange [Stephen Strange] (cameo); Luke Cage (cameo); Nighthawk [Kyle Richmond] (cameo); Hellcat [Patsy Walker]; Ruby Thursday [Thursday Rubinstein]; Dibbuk; James-Michael Starling; Moondragon [Heather Douglas]]; Wa |
| 28 | Defenders #78, Page 5 | comic story | 1 | script: Ed Hannigan; pencils: Herb Trimpe, Mike Esposito; inks: Mike Esposito; colors: Ben Sean; letters: Clem Robins | Clea; Moondragon [Heather Douglas]; Omega the Unknown (cameo, corpse) |
| 29 | Omega | character profile | 2 | script: Mark Gruenwald, Peter Sanderson; pencils: Wayne Boring; inks: Joe Rubinstein, Phil Lord, Don Hudson; colors: Andy Yanchus; letters: Brenda Mings | Omega |
| 30 | Prototypic Omega Costume | illustration | 1 | pencils: John Romita; inks: John Romita; colors: John Romita | Omega |
| 31 | The Marvel Masterworks Library | promo (ad from the publisher) | 1 | pencils: various; inks: various; colors: various; letters: typeset | |
| 32 | Man of Mystery from Beyond the Stars! | promo (ad from the publisher) | 1 | pencils: Rich Buckler; inks: Al Milgrom | Omega; Hulk [Bruce Banner] |