| 0 | - | cover | 1 | pencils: Paulo Siqueira; inks: Paulo Siqueira; colors: Marcio Menyz | Black Panther, Captain Marvel, Carol Danvers, Jim Hammond, Human Torch, Ironheart, Miles Morales, Namor, Spider-Man, Sub-Mariner, T'Challa, Riri Williams |
| 1 | Title Page and Credits | credits, title page | 3 | pencils: Brian Level; inks: Brian Level | |
| 2 | #1 Variant | cover reprint (on interior page) | 1 | pencils: Chris Samnee; inks: Chris Samnee; colors: Matthew Wilson | Namor, Sub-Mariner |
| 3 | Sanctuary | comic story | 10 | script: Paul Allor; pencils: Brian Level; inks: Brian Level; colors: Jordan Boyd; letters: VC's Joe Caramagna; editing: Charles Beacham | Bucky Barnes, Bucky, Captain America, Jim Hammond, Human Torch, Namor, Thomas Raymond, Steve Rogers, Sub-Mariner, Toro |
| 4 | Sanctuary Part 2 | comic story | 8 | script: Paul Allor; pencils: Brian Level; inks: Brian Level; colors: Jordan Boyd; letters: VC's Joe Caramagna; editing: Charles Beacham | Jim Hammond, Human Torch, Namor, Namora, Thomas Raymond, Sub-Mariner, Toro |
| 5 | Sanctuary Part 3 | comic story | 8 | script: Paul Allor; pencils: Brian Level; inks: Brian Level; colors: Jordan Boyd; letters: VC's Joe Caramagna; editing: Charles Beacham | Jim Hammond, Human Torch, Namor, Namora, Thomas Raymond, Sub-Mariner, Toro |
| 6 | Sanctuary Part 4 | comic story | 8 | script: Paul Allor; pencils: Brian Level; inks: Brian Level; colors: Jordan Boyd; letters: VC's Joe Caramagna; editing: Charles Beacham | Bucky Barnes, Jim Hammond, Human Torch, Namor, Namora, Thomas Raymond, Sub-Mariner, Toro, Winter Soldier |
| 7 | Sanctuary Part 5 | comic story | 8 | script: Paul Allor; pencils: Brian Level; inks: Brian Level; colors: Jordan Boyd; letters: VC's Joe Caramagna; editing: Charles Beacham | Bucky Barnes, Jim Hammond, Human Torch, Namor, Namora, Thomas Raymond, Sub-Mariner, Toro, Winter Soldier |
| 8 | - | cover reprint (on interior page) | 1 | pencils: Paulo Siqueira; inks: Paulo Siqueira; colors: Marcio Menyz | Black Panther, Captain Marvel, Carol Danvers, Jim Hammond, Human Torch, Ironheart, Miles Morales, Namor, Spider-Man, Sub-Mariner, T'Challa, Riri Williams |
| 9 | Mile Hydra | comic story | 6 | script: Jeremy Whitley; pencils: Diego Olortegui; inks: Diego Olortegui; colors: Andy Troy; letters: VC's Joe Caramagna; editing: Charles Beacham | Ant-Man, Blue Marvel, Adam Brashear, Giant-Man, Grizzly, Scott Lang, Machinesmith, Maxwell Markham, Samuel Saxon, Nadia Van Dyne, Wasp |
| 10 | Propagandamonium | comic story | 4 | script: Nick Kocher; pencils: Tana Ford; inks: Tana Ford; colors: Rachelle Rosenberg; letters: VC's Joe Caramagna; editing: Heather Antos | Gwenpool, Gwen Poole |
| 11 | - | cover reprint (on interior page) | 1 | pencils: Paulo Siqueira; inks: Paulo Siqueira; colors: Marcio Menyz | Patriot [Rayshaun Lucas] |
| 12 | Birth of Patriot | comic story | 9 | script: Rodney Barnes; pencils: Juan M. Frigeri; inks: Juan M. Frigeri; colors: Erick Arciniega; letters: VC's Joe Caramagna; editing: Charles Beacham | Clint Barton, Black Widow, Falcon, Giant-Man, Hawkeye, Iron Man, Miles Morales, Patriot [Rayshaun Lucas], Natasha Romanoff, Spider-Man, Tony Stark, Joaquin Torres, Simon Williams, Wonder Man |
| 13 | Bob Agent of Hydra | comic story | 4 | script: Fabian Nicieza; pencils: Will Robson; inks: Will Robson; colors: Tamra Bonvillain; letters: VC's Joe Caramagna; editing: Heather Antos | Hydra Bob |
| 14 | The Daily Bugle | cover reprint (on interior page) | 1 | pencils: Paulo Siqueira; inks: Paulo Siqueira; colors: Andy Troy | Wilson Fisk |
| 15 | Back in the Fight! | comic story | 8 | script: Ethan Sacks; pencils: Marco Lorenzana; inks: Juan Vlasco; colors: Erick Arciniega; letters: VC's Joe Caramagna; editing: Charles Beacham | Jessica Drew, J. Jonah Jameson, Kraven the Hunter, Sergei Kravinoff, Robbie Robertson, Spider-Woman, Ben Urich |
| 16 | Walls | comic story | 4 | script: Mags Visaggio; pencils: Sean Izaakse; inks: Sean Izaakse; colors: Tamra Bonvillain; letters: VC's Joe Caramagna; editing: Alanna Smith | Captain Marvel, Carol Danvers, Jim Hammond, Human Torch, Eugene Judd, Walter Langkowski, Puck, Monica Rambeau, Sasquatch, Spectrum |
| 17 | Misty Knight | cover reprint (on interior page) | 1 | pencils: Paulo Siqueira; inks: Paulo Siqueira; colors: Marcio Menyz | Misty Knight |
| 18 | The Last Place You Look | comic story | 8 | script: Karla Pacheco; pencils: Alex Arizmendi; inks: Alex Arizmendi; colors: John Rauch; letters: VC's Joe Caramagna; editing: Kathleen Wisneski | Misty Knight |
| 19 | All the World's a Stage | comic story | 4 | script: Amy Chu; pencils: Kate Niemczyk; inks: Kate Niemczyk; colors: Kate Niemczyk; letters: VC's Joe Caramagna; editing: Christina Harrington | Emma Frost, Sebastian Shaw |
| 20 | - | cover reprint (on interior page) | 1 | pencils: Paulo Siqueira; inks: Paulo Siqueira; colors: Rachelle Rosenberg | Blade, Eric Brooks |
| 21 | Lessons | comic story | 8 | script: Simon Spurrier; pencils: Wilfredo Torres; inks: Wilfredo Torres; colors: Mat Lopes; letters: VC's Joe Caramagna; editing: Wil Moss | Blade, Eric Brooks |
| 22 | Superhot | comic story | 4 | script: Leah Williams; pencils: Victor Ibáñez; inks: Victor Ibáñez; colors: Jay David Ramos; letters: VC's Joe Caramagna; editing: Chris Robinson | Domino, Emma Frost, Neena Thurman |
| 23 | - | cover reprint (on interior page) | 1 | pencils: John Cassaday; inks: John Cassaday; colors: Paul Mounts | Black Bolt, Black Widow, Blackagar Boltagon, Captain America, Captain Marvel, Carol Danvers, Deadpool, Old Man Logan, Peter Parker, Rocket Raccoon, Steve Rogers, Natasha Romanoff, Natasha Romanoff, Spider-Man |