| 0 | - | cover | 1 | pencils: Todd McFarlane; inks: Todd McFarlane; colors: Andy Troy | Eddie Brock, Peter Parker, Spider-Man, Venom |
| 1 | Graphic Novels | promo (ad from the publisher) | 1 | pencils: various; inks: various; colors: various; letters: typeset | |
| 2 | Spider-Man: Birth of Venom | credits, title page | 1 | pencils: Ron Frenz; inks: Klaus Janson, Joe Rubinstein | Peter Parker, Spider-Man |
| 3 | - | credits, title page | 2 | pencils: Greg LaRocque, Todd McFarlane; inks: Jim Mooney, Todd McFarlane | Eddie Brock, Peter Parker, Spider-Man, Venom |
| 4 | - | recap | 1 | script: Mike Fichera; pencils: Mike Zeck; inks: John Beatty; colors: Christie Scheele | |
| 5 | Marvel Super Heroes | cover reprint (on interior page) | 1 | pencils: Mike Zeck; inks: John Beatty | Amora, Bruce Banner, Clint Barton, Bulldozer, Henry Camp, Captain America, Captain Marvel, Doctor Octopus, Enchantress, Dirk Garthwaite, Ben Grimm, Hawkeye, Hulk, Human Torch |
| 6 | Marvel Super Heroes | comic story | 2 | script: Jim Shooter; pencils: Mike Zeck; inks: Mike Esposito; colors: Christie Scheele; letters: Joe Rosen | Bruce Banner, Captain America, Hulk, Peter Parker, Steve Rogers, Spider-Man, Thor, Professor X, Charles Xavier |
| 7 | - | recap | 1 | script: Mike Fichera; pencils: Mike Zeck; inks: John Beatty; colors: Christie Scheele | Peter Parker, Spider-Man |
| 8 | The Rumors are True. Introducing... the New Spider-Man! | cover reprint (on interior page) | 1 | pencils: Ron Frenz; inks: Klaus Janson; letters: Danny Fingeroth | Peter Parker, Spider-Man |
| 9 | Homecoming! | comic story | 22 | script: Roger Stern, Tom DeFalco; pencils: Ron Frenz; inks: Brett Breeding; colors: Glynis Wein; letters: Joe Rosen | Clint Barton, Black Cat, Captain America, Captain Marvel, Billy Connors, Curt Connors, Martha Connors, Felicia Hardy, Hawkeye, Iron Man, J. Jonah Jameson, Nathan Lubensky, May Parker, Peter Parker |
| 10 | - | cover reprint (on interior page) | 1 | pencils: Rick Leonardi; inks: Rick Leonardi | Richard Fisk, Peter Parker, The Rose, Spider-Man |
| 11 | By Myself Betrayed! | comic story | 23 | script: Tom DeFalco; pencils: Rick Leonardi; inks: Bill Anderson; colors: Glynis Wein; letters: Joe Rosen | Black Cat, Richard Fisk, Felicia Hardy, Nathan Lubensky, May Parker, Ben Parker, Peter Parker, Robbie Robertson, The Rose, Spider-Man |
| 12 | - | cover reprint (on interior page) | 1 | pencils: Rick Leonardi; inks: Joe Rubinstein | Jack O'Lantern, Jason Macendale Jr., Peter Parker, Spider-Man |
| 13 | With Great Power... | comic story | 22 | script: Tom DeFalco; pencils: Rick Leonardi; inks: Joe Rubinstein; colors: Christie Scheele; letters: Joe Rosen | Black Cat, Felicia Hardy, Hobgoblin, Jack O'Lantern, Roderick Kingsley, Nathan Lubensky, Jason Macendale Jr., May Parker, Peter Parker, Robbie Robertson, Spider-Man |
| 14 | Even a Ghost... ...Can Fear the Night! | cover reprint (on interior page) | 1 | pencils: Ron Frenz; inks: Joe Rubinstein | Ivan Kragoff, Peter Parker, Red Ghost, Spider-Man |
| 15 | Even a Ghost Can Fear the Night | comic story | 22 | script: Tom DeFalco; pencils: Ron Frenz; inks: Joe Rubinstein; colors: Glynis Wein; letters: Joe Rosen | Black Fox, Roderick Kingsley, Ivan Kragoff, Nathan Lubensky, May Parker, Peter Parker, Red Ghost, Spider-Man |
| 16 | - | cover reprint (on interior page) | 1 | pencils: Ron Frenz; inks: Joe Rubinstein | Thomas Fireheart, Peter Parker, Puma, Spider-Man |
| 17 | Introducing... Puma! | comic story | 22 | script: Tom DeFalco; pencils: Ron Frenz; inks: Joe Rubinstein; colors: Christie Scheele; letters: Joe Rosen | Black Cat, Thomas Fireheart, Richard Fisk, Felicia Hardy, May Parker, Peter Parker, Puma, Robbie Robertson, The Rose, Spider-Man, Mary Jane Watson |
| 18 | - | cover reprint (on interior page) | 1 | pencils: Ron Frenz; inks: Joe Rubinstein | Thomas Fireheart, Peter Parker, Puma, Spider-Man |
| 19 | Beware the Claws of Puma! | comic story | 22 | script: Tom DeFalco; pencils: Ron Frenz; inks: Joe Rubinstein; colors: Christie Scheele; letters: Joe Rosen | Arranger, Black Cat, Thomas Fireheart, Richard Fisk, Wilson Fisk, Felicia Hardy, Kingpin, Peter Parker, Puma, The Rose, Oswald Silkworth, Spider-Man, Mary Jane Watson |
| 20 | - | cover reprint (on interior page) | 1 | pencils: Ron Frenz; inks: Joe Rubinstein | Peter Parker; Spider-Man Red Costume; Spider-Man Black Costume |
| 21 | The Sinister Secret of Spider-Man's New Costume! | comic story | 23 | script: Tom DeFalco; pencils: Ron Frenz; inks: Joe Rubinstein; colors: Bob Sharen; letters: Joe Rosen | Black Cat, Thomas Fireheart, Richard Fisk, Felicia Hardy, Human Torch, Jack O'Lantern, Jason Macendale Jr., Mister Fantastic, May Parker, Peter Parker, Reed Richards, Robbie Robertson, The Rose, Spider-Man |
| 22 | The Original is Back! | cover reprint (on interior page) | 1 | pencils: Ron Frenz; inks: Joe Rubinstein | Hobgoblin, Roderick Kingsley, Peter Parker, Spider-Man, Mary Jane Watson |
| 23 | All My Pasts Remembered! | comic story | 22 | script: Tom DeFalco; pencils: Ron Frenz; inks: Joe Rubinstein; colors: Bob Sharen; letters: Joe Rosen | Peter Parker, Spider-Man |
| 24 | - | recap | 1 | script: Mike Fichera; pencils: Al Milgrom; inks: Geof Isherwood; colors: Bob Sharen | Black Cat, Felicia Hardy, Peter Parker, Spider-Man |
| 25 | - | comic story | 2 | script: John Byrne; pencils: John Byrne; inks: Al Gordon, Dan Adkins; colors: Glynis Wein; letters: Diana Albers | Venom Symbiote (as Black Costume) |
| 26 | - | comic story | 1 | script: Al Milgrom; pencils: Herb Trimpe; inks: Vince Colletta; colors: A. Kaotic; letters: Joe Rosen | Venom Symbiote (as Black Costume) |
| 27 | - | comic story | 3 | script: Al Milgrom; pencils: Al Milgrom; inks: Geof Isherwood; colors: Bob Sharen; letters: Diana Albers | Peter Parker, Spider-Man |
| 28 | - | cover reprint (on interior page) | 1 | pencils: Charles Vess; inks: Charles Vess; colors: Charles Vess | Peter Parker, Spider-Man |
| 29 | 'Til Death Do Us Part! | comic story | 22 | script: Louise Simonson; pencils: Greg LaRocque; inks: Jim Mooney, Vince Colletta; colors: George Roussos; letters: Janice Chiang, Phil Felix, Rick Parker | May Parker, Peter Parker, Spider-Man, Mary Jane Watson |
| 30 | - | recap | 1 | script: Mike Fichera; pencils: Marc Silvestri; inks: Kyle Baker; colors: Bob Sharen | Peter Parker, Spider-Man |
| 31 | - | comic story | 1 | script: David Michelinie; pencils: Todd McFarlane; inks: Bob McLeod; colors: Janet Jackson; letters: Rick Parker, Ken Lopez | Eddie Brock, Venom |
| 32 | - | comic story | 2 | script: David Michelinie; pencils: Todd McFarlane; inks: Bob McLeod; colors: Bob Sharen; letters: Rick Parker | Eddie Brock, Venom, Mary Jane Watson |
| 33 | - | cover reprint (on interior page) | 1 | pencils: Todd McFarlane; inks: Todd McFarlane | Peter Parker, Spider-Man |
| 34 | Venom | comic story | 40 | script: David Michelinie; pencils: Todd McFarlane; inks: Todd McFarlane; colors: Bob Sharen; letters: Rick Parker | Eddie Brock, Ben Grimm, Nathan Lubensky, Mister Fantastic, May Parker, Mary Jane Watson, Peter Parker, Reed Richards, Robbie Robertson, Spider-Man, The Thing, Flash Thompson, Venom |
| 35 | - | cover reprint (on interior page) | 1 | pencils: Todd McFarlane; inks: Todd McFarlane | Morrie Bench, Eddie Brock, Hydro-Man, Peter Parker, Spider-Man, Venom |
| 36 | A Matter of Life and Debt | comic story | 22 | script: David Michelinie; pencils: Todd McFarlane; inks: Todd McFarlane; colors: Bob Sharen; letters: Rick Parker | Morrie Bench, Eddie Brock, Hydro-Man, Nathan Lubensky, May Parker, Mary Jane Watson, Peter Parker, Spider-Man, Venom |
| 37 | The Truckstop of Doom! | comic story | 10 | script: David Michelinie; pencils: Paris Cullins; inks: Bud LaRosa; colors: Kevin Tinsley; letters: Rick Parker | Eddie Brock, Venom |
| 38 | Venom is Back! | cover reprint (on interior page) | 1 | pencils: Todd McFarlane; inks: Todd McFarlane | Eddie Brock, Peter Parker, Spider-Man, Venom |
| 39 | Dead Meat | comic story | 22 | script: David Michelinie; pencils: Todd McFarlane; inks: Todd McFarlane; colors: Bob Sharen; letters: Rick Parker | Black Cat, Eddie Brock, Gloria Grant, Felicia Hardy, May Parker, Mary Jane Watson, Peter Parker, Spider-Man, Venom |
| 40 | - | cover reprint (on interior page) | 1 | pencils: Todd McFarlane; inks: Todd McFarlane | Eddie Brock, Peter Parker, Spider-Man, Venom |
| 41 | The Sand and the Fury | comic story | 22 | script: David Michelinie; pencils: Todd McFarlane; inks: Todd McFarlane; colors: Bob Sharen; letters: Rick Parker | Eddie Brock, Ben Grimm, May Parker, Mary Jane Watson, Peter Parker, Spider-Man, The Thing, Venom |
| 42 | Venom | character profile | 3 | script: Peter Sanderson, Marcus McLaurin, David Wohl, Glenn Herdling, Len Kaminski; pencils: Erik Larsen, Todd McFarlane; inks: Erik Larsen, Todd McFarlane; letters: Tom Avery | Eddie Brock, Peter Parker, Spider-Man, Venom |
| 43 | - | illustration | 1 | pencils: Rick Leonardi; inks: Rick Leonardi | Peter Parker, Spider-Man |
| 44 | The Marvel Masterworks Library | promo (ad from the publisher) | 1 | pencils: various; inks: various; colors: various; letters: typeset | |
| 45 | The Origin of Venom! | promo (ad from the publisher) | 1 | pencils: Charles Vess; inks: Charles Vess; colors: Charles Vess | Peter Parker, Spider-Man |