| 0 | - | cover | 1 | pencils: Ron Lim; inks: Keith Williams; colors: Paul Mounts | Spider-Man |
| 1 | Spider-Man: the Cosmic Adventures | table of contents | 3 | letters: typeset | |
| 2 | With Greater Power... | foreword, introduction, preface, afterword | 2 | script: Peter Sanderson | |
| 3 | The Paste and the Power (or A Very Sticky Situation) | comic story | 22 | script: Gerry Conway; pencils: Sal Buscema, Mike Esposito; inks: Mike Esposito; colors: Bob Sharen; letters: Rick Parker | Spider-Man [Peter Parker]; Trapster; Kingpin; Loki; Dr. Doom; Magneto; Wizard; Mary Jane Parker; Robbie Robertson [Joe Robertson]; Stuart McPhee; Cynthia Bernhammer; J. Jonah Jameson; Martha Robertson; Nick Katzenberg; Randy Robertson; Amanda Robertson |
| 4 | With Great Power | comic story | 22 | script: Gerry Conway; pencils: Alex Saviuk; inks: Keith Williams; colors: Bob Sharen; letters: Rick Parker | Spider-Man [Peter Parker]; Puma; Titania; Doctor Doom; Nick Katzenberg; Kate Cushing [Kathryn Cushing]; Ben Urich; Joy Mercado; Mary Jane Parker |
| 5 | Cunning Attractions! | comic story | 22 | script: David Michelinie; pencils: Erik Larsen; inks: Al Gordon; colors: Bob Sharen; letters: Rick Parker | Cosmic Spider-Man (feature); Mary Jane Parker (guest); Flash Thompson (guest); Magneto (villain); Dr. Doom (cameo); Kingpin (cameo); Wizard (cameo) |
| 6 | These Shattered Senses or A Tale of the Brothers Grimm | comic story | 22 | script: Gerry Conway; pencils: Sal Buscema, Mike Esposito; inks: Mike Esposito; colors: Bob Sharen; letters: Rick Parker | Spider-Man [Peter Parker]; Brothers Grimm; Dr. Doom; Wizard; Stuart McPhee; Cynthia Bernhammer; J. Jonah Jameson |
| 7 | The Harder They Fall | comic story | 22 | script: Gerry Conway; pencils: Alex Saviuk; inks: Keith Williams; colors: Bob Sharen; letters: Rick Parker | Spider-Man [Peter Parker]; Goliath [Erik Josten]; Kingpin; Magneto; Doctor Doom; May Parker; Nathan Lubensky; Thomas Fireheart [Puma]; Gloria Grant; Kate Cushing [Kathryn Cushing]; Nick Katzenberg |
| 8 | Shaw's Gambit | comic story | 23 | script: David Michelinie; pencils: Todd McFarlane; inks: Todd McFarlane; colors: Bob Sharen; letters: Rick Parker | Cosmic Spider-Man; Hulk; Mary Jane Parker; Flash Thompson; Sebastian Shaw (villain) |
| 9 | The Fear and the Fury or: The Metal in Men's Souls | comic story | 22 | script: Gerry Conway; pencils: Sal Buscema; inks: Sal Buscema; colors: Bob Sharen; letters: Rick Parker | Spider-Man [Peter Parker]; T.E.S.S.-One; Dr. Doom; Loki; Kingpin; Cynthia Bernhammer; Stuart McPhee; Mary Jane Parker; J. Jonah Jameson; Marla Madison Jameson; Nick Katzenberg; Captain Universe; Rhino; Shocker; Hydro-Man |
| 10 | Dragon in the Dark | comic story | 22 | script: Gerry Conway; pencils: Alex Saviuk; inks: Keith Williams; colors: Bob Sharen; letters: Rick Parker | Spider-Man [Peter Parker]; Dragon Man; Wizard; Mandarin; Magneto; Doctor Doom; Red Skull; Kingpin; Loki; Mary Jane Parker; Kristy Watson; Harry Osborn; Liz Allan Osborn; Norman Osborn II; Molten Man (cameo) |
| 11 | Power Prey! | comic story | 22 | script: David Michelinie; pencils: Erik Larsen; inks: Andy Mushynsky; colors: Bob Sharen; letters: Rick Parker | Captain Universe [Spider-Man]; Mary Jane Parker (guest); Sebastian Shaw (villain); Graviton (villain); Tri-Sentinel (villain); Loki (cameo); Felicia Hardy [Black Cat] (cameo); Flash Thompson (cameo) |
| 12 | ...Must Come Greater Responsibility | foreword, introduction, preface, afterword | 1 | script: Peter Sanderson | |
| 13 | With Greater Power... | cover reprint (on interior page) | 1 | pencils: Sal Buscema; inks: Sal Buscema | Spider-Man [Peter Parker]; Trapster |
| 14 | - | cover reprint (on interior page) | 0.5 | pencils: Alex Saviuk; inks: Alex Saviuk | Spider-Man [Peter Parker]; Puma; Titania; Nick Katzenberg; Ben Urich; Joy Mercado |
| 15 | Spidey Faces the X-Men's Toughest Foe -- Magneto! | cover reprint (on interior page) | 0.5 | pencils: Erik Larsen; inks: Al Gordon | Spider-Man; Magneto |
| 16 | Look!! Nothing Can Stop Him Now! He Can Fly!! | cover reprint (on interior page) | 0.5 | pencils: Sal Buscema; inks: Sal Buscema | Spider-Man [Peter Parker]; Brothers Grimm |
| 17 | At the Core's Command-- Goliath Strikes! | cover reprint (on interior page) | 0.5 | pencils: Alex Saviuk; inks: Alex Saviuk; letters: Phil Felix | Spider-Man [Peter Parker]; Goliath [Erik Josten]; Kingpin (vignette); Magneto (vignette); Doctor Doom (vignette) |
| 18 | Now Who's The Strongest One There Is?! | cover reprint (on interior page) | 0.5 | pencils: Todd McFarlane; inks: Todd McFarlane | Spider-Man; Hulk |
| 19 | - | cover reprint (on interior page) | 0.5 | pencils: Sal Buscema; inks: Sal Buscema | Spider-Man [Peter Parker]; T.E.S.S.-One; Dr. Doom; Hydro-Man; Rhino; Shocker |
| 20 | Roasted by Dragon Man! | cover reprint (on interior page) | 0.5 | pencils: Alex Saviuk; inks: Andy Mushynsky | Spider-Man [Peter Parker]; Dragon Man |
| 21 | Introducing--The Tri-Sentinel | cover reprint (on interior page) | 0.5 | pencils: Erik Larsen; inks: Al Gordon | Spider-Man; Tri-Sentinel |