| 0 | - | cover | 1 | pencils: Scott McDaniel; inks: Klaus Janson; colors: Kevin Tinsley | Eddie Brock, Carnage, Doctor Octopus, Green Goblin, Jackal, J. Jonah Jameson, Cletus Kasady, Otto Octavius, Norman Osborn, Ben Parker, May Parker, Peter Parker, Robbie Robertson, Spider-Man |
| 1 | Title Page and Credits | credits, title page | 3 | colors: John Marasigan; letters: John Marasigan | |
| 2 | The Origin of the Amazing Spider-Man! | comic story | 3 | script: David Michelinie; pencils: Sal Buscema; inks: Sal Buscema; colors: Evan Skolnick; letters: Chris Eliopoulos; editing: Danny Fingeroth | The Burglar, Ben Parker, May Parker, Peter Parker, Spider-Man |
| 3 | - | character profile | 4 | script: Mark Bernardo, Peter Sanderson, Bob Budiansky; letters: Comicraft's John Marasigan | |
| 4 | Peter Parker | character profile | 1 | script: Mark Bernardo, Peter Sanderson, Bob Budiansky; letters: Comicraft's John Marasigan | Peter Parker |
| 5 | Friends of Spider-Man | character profile | 8 | script: Mark Bernardo, Peter Sanderson, Bob Budiansky; letters: Comicraft's John Marasigan | Liz Allan, Betty Brant, J. Jonah Jameson, John Jameson, Dr. Ashley Kafka, Ned Leeds, Harry Osborn, Ben Parker, May Parker, Robbie Robertson, George Stacy, Gwen Stacy, Flash Thompson, Ben Urich |
| 6 | Web of Life | illustration | 2 | letters: Comicraft's John Marasigan | Liz Allan, Betty Brant, Eddie Brock, Carnage, Doctor Octopus, Mac Gargan, Hobgoblin, Jackal, J. Jonah Jameson, John Jameson, Dr. Ashley Kafka, Kaine, Cletus Kasady, Roderick Kingsley |
| 7 | Enemies | character profile | 23 | script: Mark Bernardo, Peter Sanderson, Bob Budiansky; letters: Comicraft's John Marasigan | Quentin Beck, Beetle, Morrie Bench, Eddie Brock, Carnage, Chameleon, Curt Connors, Max Dillon, Doctor Octopus, Electro, Norton Fester, Thomas Fireheart, Richard Fisk, Wilson Fisk |
| 8 | Spider-Man Rates His Opponents | text story | 2 | script: Mark Bernardo, Peter Sanderson, Bob Budiansky; letters: Comicraft's John Marasigan | |
| 9 | Allies | character profile | 10 | script: Mark Bernardo, Peter Sanderson, Bob Budiansky; letters: Comicraft's John Marasigan | Jackson Arvad, Black Cat, Hobie Brown, Frank Castle, Daredevil, Felicia Hardy, Human Torch, Flint Marko, Molten Man, Matt Murdock, Prowler, Punisher, Mark Raxton, Ben Reilly |
| 10 | Daily Bugle | character profile | 1 | script: Mark Bernardo, Peter Sanderson, Bob Budiansky; letters: Comicraft's John Marasigan | |
| 11 | Empire State University | character profile | 0.5 | script: Mark Bernardo, Peter Sanderson, Bob Budiansky; letters: Comicraft's John Marasigan | |
| 12 | Midtown High School | character profile | 0.5 | script: Mark Bernardo, Peter Sanderson, Bob Budiansky; letters: Comicraft's John Marasigan | |
| 13 | Spider-Man's First Appearance | text article | 5 | script: Mark Bernardo, Peter Sanderson, Bob Budiansky; pencils: Jack Kirby; inks: Steve Ditko; colors: Stan Goldberg; letters: Comicraft's John Marasigan | |