| 0 | Sinister Six | cover | 1 | pencils: Marcos Martín; inks: Marcos Martín; colors: Marcos Martín | Beetle, James Beverley, Boomerang, Janice Lincoln, Fred Myers, Overdrive, James Sanders, Herman Schultz, Shocker, Speed Demon |
| 1 | Title Page, Credits and Indicia | credits, title page | 1 | letters: typeset | |
| 2 | Sinister Six | cover reprint (on interior page) | 1 | pencils: Marcos Martín; inks: Marcos Martín; colors: Marcos Martín | Sinister Six [Boomerang; Shocker; Beetle; Overdrive; Speed Demon] |
| 3 | Recap | recap | 1 | pencils: Marcos Martín; inks: Marcos Martín; colors: Marcos Martín | Sinister Six [Boomerang; Shocker; Beetle; Overdrive; Speed Demon] |
| 4 | Sinister Six | comic story | 20 | script: Nick Spencer; pencils: Steve Lieber; inks: Steve Lieber; colors: Rachelle Rosenberg; letters: Joe Caramagna | Sinister Six [Boomerang (origin flashback); Overdrive; Beetle; Speed Demon; Shocker]; Hammerhead; Chameleon; Spider-Man (flashback); Secret Empire (flashback); SHIELD (flashback); Silver Sable (flashback); Rhino (flashback) |
| 5 | Sinister Six | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Morry Hollowell | Sinister Six [Boomerang; Shocker; Overdrive; Beetle; Speed Demon] |
| 6 | Sinister Six | comic story | 20 | script: Nick Spencer; pencils: Steve Lieber; inks: Steve Lieber; colors: Rachelle Rosenberg; letters: VC, Joe Caramagna | Sinister Six [Boomerang; Shocker; Overdrive; Beetle; Speed Demon]; Chameleon [also as Punisher]; Partridge; Mach VII [Abner Jenkins] |
| 7 | Sinister Six | cover reprint (on interior page) | 1 | pencils: Michael Del Mundo; inks: Michael Del Mundo; colors: Michael Del Mundo | Sinister Six [Boomerang; Shocker; Overdrive; Beetle; Speed Demon]; Benjamin Franklin |
| 8 | Sinister Six | comic story | 20 | script: Nick Spencer; pencils: Steve Lieber; inks: Steve Lieber; colors: Rachelle Rosenberg; letters: VC, Joe Caramagna | Sinister Six [Boomerang; Shocker; Overdrive; Beetle; Speed Demon]; Silvermane (flashback); Maggia (flashback); Owl (flashback); Hammerhead (flashback); Mach VII [Abner Jenkins]; Masters of Evil [Baron Zemo; Fixer; Beetle; Goliath; Moonstone; Screaming Mimi] (flashback); Thunderbolts [Techno; Meteori |
| 9 | Sinister Six | cover reprint (on interior page) | 1 | pencils: Paulo Siqueira; inks: Paulo Siqueira; colors: Marte Gracia | Sinister Six [Boomerang; Shocker; Overdrive; Beetle; Speed Demon] |
| 10 | Sinister Six | comic story | 20 | script: Nick Spencer; pencils: Steve Lieber; inks: Steve Lieber; colors: Rachelle Rosenberg; letters: Joe Caramagna | Sinister Six [Boomerang; Shocker; Overdrive; Beetle; Speed Demon]; Luke Cage; Iron Fist; Chameleon; Beetle [Abner Jenkins] (flashback); Rhino (flashback); Sandman (flashback); Whiplash (flashback); Blizzard (flashback); Thunderbolts [Songbird; Man-Thing; Troll [Gunna]] (flashback) |
| 11 | Sinister Six | cover reprint (on interior page) | 1 | pencils: Steve Lieber; inks: Steve Lieber; colors: Steve Lieber | Sinister Six [Boomerang; Shocker; Overdrive; Beetle; Speed Demon] |
| 12 | Sinister Six | comic story | 20 | script: Nick Spencer; pencils: Steve Lieber; inks: Steve Lieber; colors: Rachelle Rosenberg; letters: Joe Caramagna | Sinister Six [Boomerang; Shocker; Overdrive; Beetle; Speed Demon]; Doctor Doom (flashback); Broudaire (flashback); Owl; Mach VII [Abner Jenkins]; Chameleon; Tombstone |