| 0 | - | cover | 1 | pencils: Ryan Stegman; inks: Ryan Stegman; colors: Edgar Delgado | Otto Octavius, Spider-Man |
| 1 | - | cover reprint (on interior page) | 1 | pencils: Ryan Stegman; inks: Ryan Stegman; colors: Edgar Delgado | Otto Octavius, Spider-Man |
| 2 | Hero or Menace? | comic story | 21 | script: Dan Slott; pencils: Ryan Stegman; inks: Ryan Stegman; colors: Edgar Delgado; letters: Chris Eliopoulos | Otto Octavius, Peter Parker, James Sanders, Grady Scraps, Speed Demon, Spider-Man, Mary Jane Watson, Beetle, James Beverley, Boomerang, Janice Lincoln, The Living Brain, Fred Myers, Overdrive |
| 3 | - | cover reprint (on interior page) | 1 | pencils: Ryan Stegman; inks: Ryan Stegman; colors: Edgar Delgado | Otto Octavius, Spider-Man, Mary Jane Watson |
| 4 | The Peter Principle | comic story | 19 | script: Dan Slott; pencils: Ryan Stegman; inks: Ryan Stegman; colors: Edgar Delgado; letters: Chris Eliopoulos | Carlie Cooper, J. Jonah Jameson, Otto Octavius, Peter Parker, Spider-Man, Mary Jane Watson |
| 5 | - | cover reprint (on interior page) | 1 | pencils: Ryan Stegman; inks: Ryan Stegman; colors: Edgar Delgado | Otto Octavius, Spider-Man |
| 6 | Everything You Know Is Wrong | comic story | 20 | script: Dan Slott; pencils: Ryan Stegman; inks: Ryan Stegman; colors: Edgar Delgado; letters: Chris Eliopoulos | Carlie Cooper, J. Jonah Jameson, Otto Octavius, Peter Parker, Spider-Man, Adrian Toomes, The Vulture |
| 7 | - | cover reprint (on interior page) | 1 | pencils: Giuseppe Camuncoli; inks: John Dell; colors: Edgar Delgado | Peter Parker, Spider-Man |
| 8 | The Aggressive Approach | comic story | 20 | script: Dan Slott; pencils: Giuseppe Camuncoli; inks: John Dell; colors: Edgar Delgado; letters: Chris Eliopoulos | J. Jonah Jameson, Otto Octavius, May Parker, Peter Parker, Spider-Man |
| 9 | - | cover reprint (on interior page) | 1 | pencils: Giuseppe Camuncoli; inks: John Dell | Otto Octavius, Spider-Man |
| 10 | Emotional Trigger | comic story | 20 | script: Dan Slott; pencils: Giuseppe Camuncoli; inks: John Dell, Giuseppe Camuncoli; colors: Edgar Delgado, Chris Sotomayor, Antonio Fabela; letters: Chris Eliopoulos | Anna Maria Marconi, Otto Octavius, Peter Parker, Spider-Man |
| 11 | - | cover reprint (on interior page) | 1 | pencils: Joe Quesada; inks: Danny Miki; colors: Richard Isanove | Otto Octavius, Spider-Man |
| 12 | - | cover reprint (on interior page) | 1 | pencils: Skottie Young; inks: Skottie Young; colors: Skottie Young | Spider-Man |
| 13 | - | cover reprint (on interior page) | 1 | pencils: Humberto Ramos; inks: Humberto Ramos; colors: Edgar Delgado | Otto Octavius, Spider-Man |
| 14 | - | cover reprint (on interior page) | 1 | pencils: Giuseppe Camuncoli; inks: John Dell; colors: Edgar Delgado | Otto Octavius, Spider-Man |
| 15 | - | cover reprint (on interior page) | 2 | pencils: J. Scott Campbell; inks: J. Scott Campbell; colors: Edgar Delgado | Mary Jane Watson |
| 16 | Ed McGuinness Design Variant Cover | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; letters: Ed McGuinness | Otto Octavius, Spider-Man |
| 17 | - | cover reprint (on interior page) | 0.5 | pencils: Mike Deodato Jr.; inks: Mike Deodato Jr.; colors: Rain Beredo | Otto Octavius, Spider-Man, Beetle, Boomerang, Janice Lincoln, The Living Brain, Fred Myers, James Sanders, Herman Schultz, Shocker, Speed Demon |
| 18 | - | cover reprint (on interior page) | 0.5 | pencils: Adi Granov; inks: Adi Granov; colors: Adi Granov | Otto Octavius, Spider-Man |
| 19 | - | cover reprint (on interior page) | 0.25 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Marte Gracia | Otto Octavius, Spider-Man |
| 20 | - | cover reprint (on interior page) | 0.25 | pencils: Simone Bianchi; inks: Simone Bianchi; colors: Simone Peruzzi | Otto Octavius, Spider-Man, Adrian Toomes, The Vulture |
| 21 | - | cover reprint (on interior page) | 0.25 | pencils: Mike Deodato Jr.; colors: Rain Beredo | Otto Octavius, Spider-Man |
| 22 | - | cover reprint (on interior page) | 0.25 | pencils: Mark Bagley; inks: Mark Farmer; colors: Marte Gracia | Otto Octavius, Spider-Man |