| 0 | - | cover | 1 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | Peter Parker, Spider-Man |
| 1 | - | promo (ad from the publisher) | 1 | pencils: Stefano Caselli; inks: Stefano Caselli; colors: David Curiel | |
| 2 | Title Page and Credits | credits, title page | 3 | pencils: Marco Checchetto; inks: Marco Checchetto | |
| 3 | - | cover reprint (on interior page) | 1 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | Peter Parker, Spider-Man |
| 4 | January | comic story | 40 | script: Jonathan Hickman; pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson; letters: VC's Cory Petit | Betty Brant, Wilson Fisk, Green Goblin, Iron Lad, J. Jonah Jameson, Matt Murdock, Harry Osborn, Ben Parker, May Parker, Peter Parker, Richard Parker, Robbie Robertson, Spider-Man, Tony Stark |
| 5 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: David Marquez; inks: David Marquez; colors: Marte Gracia | |
| 6 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: Tony Daniel; inks: Tony Daniel; colors: Jay David Ramos | |
| 7 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: J. Scott Campbell; inks: J. Scott Campbell; colors: Sabine Rich | |
| 8 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: Nic Klein; inks: Nic Klein; colors: Nic Klein | |
| 9 | - | cover reprint (on interior page) | 1 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | Green Goblin, Harry Osborn, Peter Parker, Spider-Man |
| 10 | February | comic story | 24 | script: Jonathan Hickman; pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson; letters: VC's Cory Petit | Henri Dugarry, Wilson Fisk, Green Goblin, J. Jonah Jameson, Harry Osborn, Ben Parker, May Parker, Peter Parker, Richard Parker, Herman Schultz, Shocker, Spider-Man, Mary Jane Watson |
| 11 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: Ryan Stegman; inks: JP Mayer; colors: Matt Milla | |
| 12 | #1 2nd Printing Variant | cover reprint (on interior page) | 0.25 | pencils: R. B. Silva; inks: R. B. Silva; colors: R. B. Silva | |
| 13 | #1 3nd Printing Variant | cover reprint (on interior page) | 0.25 | pencils: Sara Pichelli; inks: Sara Pichelli; colors: Matthew Wilson | Peter Parker, Spider-Man |
| 14 | #2 Variant | cover reprint (on interior page) | 0.25 | pencils: Dike Ruan; inks: Dike Ruan; colors: Matthew Wilson | |
| 15 | - | cover reprint (on interior page) | 1 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | Bullseye, Green Goblin, Lester, Harry Osborn, Peter Parker, Spider-Man |
| 16 | March | comic story | 21 | script: Jonathan Hickman; pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson; letters: VC's Cory Petit | Bullseye, Green Goblin, J. Jonah Jameson, Lester, Harry Osborn, Ben Parker, May Parker, Peter Parker, Richard Parker, Spider-Man, Mary Jane Watson |
| 17 | - | cover reprint (on interior page) | 1 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | Peter Parker, Spider-Man |
| 18 | April | comic story | 21 | script: Jonathan Hickman; pencils: David Messina; inks: David Messina; colors: Matthew Wilson; letters: VC's Cory Petit | J. Jonah Jameson, Harry Osborn, Ben Parker, May Parker, Peter Parker, Richard Parker, Gwen Stacy, Mary Jane Watson |
| 19 | - | cover reprint (on interior page) | 1 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | Green Goblin, Harry Osborn, Norman Osborn, Ben Parker, Peter Parker, Spider-Man |
| 20 | May | comic story | 22 | script: Jonathan Hickman; pencils: David Messina; inks: David Messina; colors: Matthew Wilson; letters: VC's Cory Petit, VC's Joe Sabino | Bullseye, Wilson Fisk, Green Goblin, Kingpin, Lester, Otto Octavius, Emily Lyman-Osborn, Harry Osborn, Norman Osborn, Peter Parker, Herman Schultz, Shocker, Gwen Stacy |
| 21 | #2 3rd Printing Variant | cover reprint (on interior page) | 0.25 | pencils: Peach Momoko; inks: Peach Momoko; colors: Peach Momoko | |
| 22 | #3 Variant | cover reprint (on interior page) | 0.25 | pencils: Greg Land; inks: Greg Land; colors: Paul Mounts | |
| 23 | #3 Variant | cover reprint (on interior page) | 0.25 | pencils: Mike Del Mundo; inks: Mike Del Mundo; colors: Mike Del Mundo | |
| 24 | #3 2nd Printing Ratio Variant | cover reprint (on interior page) | 0.25 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | |
| 25 | - | cover reprint (on interior page) | 1 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | Wilson Fisk, Kingpin, Peter Parker, Spider-Man |
| 26 | June | comic story | 20 | script: Jonathan Hickman; pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson; letters: VC's Cory Petit | Wilson Fisk, Green Goblin, Kingpin, Harry Osborn, May Parker, Peter Parker, Richard Parker, Spider-Man, Mary Jane Watson |
| 27 | #1 Design Variant | cover reprint (on interior page) | 1 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Marco Checchetto | |
| 28 | #2 2nd Printing Design Variant | cover reprint (on interior page) | 1 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Marco Checchetto | |
| 29 | #1 Costume Tease A Variant | cover reprint (on interior page) | 0.2 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | |
| 30 | #1 Costume Tease B Variant | cover reprint (on interior page) | 0.2 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | |
| 31 | #1 Costume Tease C Variant | cover reprint (on interior page) | 0.2 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | |
| 32 | #1 6th Printing Variant | cover reprint (on interior page) | 0.2 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | |
| 33 | #3 3rd Printing Variant | cover reprint (on interior page) | 0.2 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Matthew Wilson | Superior Spider-Man |
| 34 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: Elizabeth Torque; inks: Elizabeth Torque; colors: Elizabeth Torque | |
| 35 | #2 Variant | cover reprint (on interior page) | 0.25 | pencils: Elizabeth Torque; inks: Elizabeth Torque; colors: Tamra Bonvillain | |
| 36 | #3 Variant | cover reprint (on interior page) | 0.25 | pencils: Elizabeth Torque; inks: Elizabeth Torque; colors: Tamra Bonvillain | |
| 37 | #4 Variant | cover reprint (on interior page) | 0.25 | pencils: Elizabeth Torque; inks: Elizabeth Torque; colors: Ian Herring | |
| 38 | #4 Variant | cover reprint (on interior page) | 0.25 | pencils: Kael Ngu; inks: Kael Ngu; colors: Kael Ngu | |
| 39 | #4 Variant | cover reprint (on interior page) | 0.25 | pencils: Sanford Greene; inks: Sanford Greene; colors: Sanford Greene | |
| 40 | #5 Variant | cover reprint (on interior page) | 0.25 | pencils: David Messina; inks: David Messina; colors: Edgar Delgado | |
| 41 | #5 Variant | cover reprint (on interior page) | 0.25 | pencils: Leonardo Romero; inks: Leonardo Romero; colors: Leonardo Romero | |
| 42 | #6 Variant | cover reprint (on interior page) | 0.25 | pencils: Chris Samnee; inks: Chris Samnee; colors: Matthew Wilson | |
| 43 | #6 Variant | cover reprint (on interior page) | 0.25 | pencils: David Marquez; inks: David Marquez; colors: Jesus Aburtov | |
| 44 | #1-3 Connecting Variants | cover reprint (on interior page) | 1 | pencils: Mark Bagley; inks: Mark Bagley; colors: Edgar Delgado | |
| 45 | #1 Ultimate Special Variant | cover reprint (on interior page) | 0.25 | pencils: Mateus Manhanini; inks: Mateus Manhanini; colors: Mateus Manhanini | |
| 46 | #2 Ultimate Special Variant | cover reprint (on interior page) | 0.25 | pencils: Mateus Manhanini; inks: Mateus Manhanini; colors: Mateus Manhanini | |
| 47 | #3 Ultimate Special Variant | cover reprint (on interior page) | 0.25 | pencils: Mateus Manhanini; inks: Mateus Manhanini; colors: Mateus Manhanini | |
| 48 | #4 Ultimate Special Variant | cover reprint (on interior page) | 0.25 | pencils: Mateus Manhanini; inks: Mateus Manhanini; colors: Mateus Manhanini | |
| 49 | #5 Ultimate Special Variant | cover reprint (on interior page) | 0.25 | pencils: Mateus Manhanini; inks: Mateus Manhanini; colors: Mateus Manhanini | |
| 50 | #6 Ultimate Special Variant | cover reprint (on interior page) | 0.25 | pencils: Mateus Manhanini; inks: Mateus Manhanini; colors: Mateus Manhanini | |
| 51 | - | promo (ad from the publisher) | 1 | pencils: Peach Momoko; inks: Peach Momoko; colors: Peach Momoko | |
| 52 | - | promo (ad from the publisher) | 1 | letters: typeset | |