From the editorial file The best-selling single comic book of all time by print run, October 1991, shipped in five variant covers by Jim Lee. Enormously common in any grade, which is precisely why it matters historically: this is the issue that proved variants could move numbers.
First appearance of Fabian Cortez - the earliest non-flashback appearance on record for this character.
First appearance of Marco Delgado - the earliest non-flashback appearance on record for this character.
First appearance of Anne-Marie Cortez - the earliest non-flashback appearance on record for this character.
First appearance of Chrome - the earliest non-flashback appearance on record for this character.
First appearance of Allen Marc Yuricic - the earliest non-flashback appearance on record for this character.
First appearance of Nance Winters - the earliest non-flashback appearance on record for this character.
The evidence
Claims here come from the story records for this issue, listed under Sources at the bottom of the file. Character hubs with full evidence tables are coming to this site.