| 0 | - | cover | 1 | pencils: Andrea Sorrentino; inks: Andrea Sorrentino; colors: Marcelo Maiolo | Andrew Bennett; Cain; Lucifer |
| 1 | - | cover reprint (on interior page) | 1 | pencils: Clayton Crain; inks: Clayton Crain; colors: Clayton Crain | Andrew Bennett; Cain |
| 2 | Break My Body | comic story | 20 | script: Joshua Hale Fialkov; pencils: Andrea Sorrentino; inks: Andrea Sorrentino; colors: Marcelo Maiolo; letters: Pat Brosseau | Andrew Bennett (origin); Cain; Mary Seward |
| 3 | - | cover reprint (on interior page) | 1 | pencils: Clayton Crain; inks: Clayton Crain; colors: Clayton Crain | Andrew Bennett; Deborah Dancer |
| 4 | Debaser | comic story | 20 | script: Joshua Hale Fialkov; pencils: Andrea Sorrentino; inks: Andrea Sorrentino; colors: Marcelo Maiolo; letters: Saida Temofonte | Andrew Bennett; Deborah Dancer; John Troughton; Mishkin (a dog); Tig Rafelson; Mary, Queen of Blood [Mary Seward] |
| 5 | - | cover reprint (on interior page) | 1 | pencils: Andrea Sorrentino; inks: Andrea Sorrentino; colors: Marcelo Maiolo | Andrew Bennett |
| 6 | Winterlong | comic story | 20 | script: Joshua Hale Fialkov; pencils: Andrea Sorrentino; inks: Andrea Sorrentino; colors: Marcelo Maiolo; letters: Dezi Sienty | Andrew Bennett; Charles Francis Thompson (first appearance); Deborah Dancer; John Troughton; Manny; Mary, Queen of Blood [Mary Seward]; Mishkin (a dog); Sven; Tig Rafelson |
| 7 | - | cover reprint (on interior page) | 1 | pencils: Guillem March; inks: Guillem March; colors: Tomeu Morey | Andrew Bennett; Tig Rafelson |
| 8 | Here Comes Your Man | comic story | 20 | script: Joshua Hale Fialkov; pencils: Dennis Calero; inks: Dennis Calero; colors: Marcelo Maiolo; letters: Taylor Esposito | Andrew Bennett; Bartholomew (flashback); Cain; Charles Francis Thompson; Deborah Dancer; John Troughton; Mary, Queen of Blood [Mary Seward]; Mishkin (a dog); Tig Rafelson; The Van Helsings |
| 9 | - | cover reprint (on interior page) | 1 | pencils: Alex Garner; inks: Alex Garner; colors: Alex Garner | Cain |
| 10 | Nimrod's Son | comic story | 20 | script: Joshua Hale Fialkov; pencils: Scott Clark, Fernando Blanco, Szymon Kudranski; inks: Scott Clark, Fernando Blanco, Szymon Kudranski, Dave Beaty; colors: Marcelo Maiolo; letters: Taylor Esposito | Andrew Bennett; Cain; Charles Francis Thompson; Deborah Dancer; John Constantine; John Troughton; Lilith (flashback); Mary, Queen of Blood [Mary Seward]; Mishkin (a dog); Tig Rafelson; The Van Helsings |
| 11 | - | cover reprint (on interior page) | 1 | pencils: Andrea Sorrentino; inks: Andrea Sorrentino; colors: Marcelo Maiolo | Andrew Bennett; John Constantine |
| 12 | Wave of Mutilation | comic story | 20 | script: Joshua Hale Fialkov; pencils: Fernando Blanco; inks: Fernando Blanco; colors: Marcelo Maiolo; letters: Taylor Esposito | Andrew Bennett; Cain; Charles Francis Thompson; Deborah Dancer; John Constantine; John Troughton; Mary Seward; Mishkin (a dog); The Keeper; Tig Rafelson |
| 13 | - | cover reprint (on interior page) | 1 | pencils: Andrea Sorrentino; inks: Andrea Sorrentino; colors: Marcelo Maiolo | Andrew Bennett; Mary Seward |
| 14 | Dig for Fire | comic story | 20 | script: Joshua Hale Fialkov; pencils: Fernando Blanco; inks: Fernando Blanco; colors: Marcelo Maiolo; letters: Taylor Esposito | Andrew Bennett; Cain; Charles Francis Thompson; Deborah Dancer; John Constantine; Lilith; Mary Seward; The Keeper; Tig Rafelson |
| 15 | - | cover reprint (on interior page) | 1 | pencils: Andrea Sorrentino; inks: Andrea Sorrentino; colors: Marcelo Maiolo | Andrew Bennett; Cain; Lucifer |
| 16 | Caribou | comic story | 20 | script: Joshua Hale Fialkov; pencils: Fernando Blanco, Andrea Sorrentino; inks: Fernando Blanco, Andrea Sorrentino; colors: Marcelo Maiolo; letters: Carlos M. Mangual | Andrew Bennett; Cain; Charles Francis Thompson; Deborah Dancer; John Constantine; Lilith; Lucifer; Mary Seward; Mishkin (a dog); Mr. Bennett (flashback); The Keeper (death); Tig Rafelson |
| 17 | I, Vampire Issue #17 Layouts by Fernando Blanco | illustration | 2 | pencils: Fernando Blanco; inks: Fernando Blanco | |
| 18 | I, Vampire Issue #18 and #19 Layouts by Fernando Blanco | illustration | 2 | pencils: Fernando Blanco; inks: Fernando Blanco; colors: Fernando Blanco | |
| 19 | I, Vampire Cover Sketches | illustration | 4 | pencils: Andrea Sorrentino, Guillem March, Alex Garner; inks: Andrea Sorrentino, Guillem March, Alex Garner; colors: Marcelo Maiolo | |
| 20 | - | cover reprint (on interior page) | 2 | pencils: Andrea Sorrentino; inks: Andrea Sorrentino; colors: Marcelo Maiolo | Andrew Bennett; Cain; Lucifer |