| 0 | Take a Trip With This Issue of Mad | cover | 1 | letters: typeset | |
| 1 | - | letters page | 1 | script: Jerry De Fuccio | |
| 2 | Haunted By the Ghost of Christmas Presents? | promo (ad from the publisher) | 1 | pencils: George Woodbridge; inks: George Woodbridge | Alfred E. Neuman [as The Ghost of Christmas Presents]; Ebeneezer Scrooge |
| 3 | Dirtier By the Dozen | comic story | 6 | script: Lou Silverstone; pencils: Mort Drucker; inks: Mort Drucker | Lee Marvin [as Major Roughman]; Ernest Borgnine [as General Wargum]; Charles Bronson [as Joseph Coleslaw]; Donald Sutherland [as Vernon Punkley]; John Cassavetes [as Victor Psycho]; Trini Lopez [as Jose Jimenez]; Telly Savalas [as Maggotty [The Avenging Angel]]; Clint Walker [as Samuel Pansy]; Jim B |
| 4 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 5 | Mad's Christmas Cards to Seasonal Exploiters | comic story | 3 | script: Frank Jacobs; pencils: Jack Rickard, Jack Davis, Don Martin, Bob Clarke, George Woodbridge, Dave Berg; inks: Jack Rickard, Jack Davis, Don Martin, Bob Clarke, George Woodbridge, Dave Berg | |
| 6 | A San Francisco Trip | comic story | 2 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 7 | Mad's Theatrical Agent of the Year | comic story | 4 | script: Lou Silverstone; pencils: Bruce Stark; inks: Bruce Stark | Steve Allen; John Wayne; Pat Wayne; Marlo Thomas; Gary Lewis; Jerry Lewis; Ed Sullivan; Peter Fonda; Nancy Sinatra; Steve Allen, Jr. |
| 8 | Spy Vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy, The White Spy |
| 9 | A Celebrity's Wallet | comic story | 2 | script: Arnie Kogen; letters: Bob Clarke | |
| 10 | The Lighter Side of Friendship | comic story | 4 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 11 | You Know You're Really Getting Old When... | comic story | 1 | script: Phil Hahn, Jack Hanrahan; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 12 | "Best Sellers" We're Sure to See | comic story | 3 | script: Larry Siegel; pencils: Jack Rickard; inks: Jack Rickard | |
| 13 | The Werewolf | comic story | 1 | pencils: George Woodbridge; inks: George Woodbridge | Lon Chaney Jr. [as Larry Talbot] |
| 14 | Late Night TV Roulette | photo story | 3 | script: Arnie Kogen | Johnny Carson; Ed McMahon; John Wayne [as Capt. Nathan Brittles]; The Supremes [Diana Ross; Mary Wilson; Florence Ballard]; Ronald Reagan; Nancy Reagan; Buddy Hackett; Hubert Humphrey |
| 15 | More Announcements For Everything | text story | 2 | script: Frank Jacobs | |
| 16 | Songs of Pets | comic story | 3 | script: Frank Jacobs; pencils: George Woodbridge; inks: George Woodbridge | |
| 17 | On the Road | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 18 | Ads We Never Got to See | comic story | 3 | script: Dick DeBartolo; pencils: Bob Clarke; inks: Bob Clarke | |
| 19 | The Joe Nasty Show | comic story | 4 | script: Larry Siegel; pencils: Jack Davis; inks: Jack Davis | Joe Nasty; Dr. Harris Saint; La La LaBore |
| 20 | What Will Be the Ultimate Idea in "Mod" Fashions? | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 21 | Surgical Scar | photo story | 1 | script: Max Brandel; pencils: Max Brandel; inks: Max Brandel; colors: Max Brandel | Lyndon Johnson |